Study sets matching "oncology"

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Study sets matching "oncology"

oncology
Histopathology
cytology
malignancy
sarcoidosis
[名]组织病理学
n.[生]细胞学
[名]恶性肿瘤
[名]结节病
Histopathology
[名]组织病理学
cytology
n.[生]细胞学
34 terms
Oncology
CTLA-4
Ipilimumab
B-RAF
Sorafenib
Also called CD152... Surface of T cells ... Down regulates... Fusion w…
CTLA-4 antagonist in metastatic melanoma
Protooncogene ... If mutated to be constitutively active - cance…
V600E inhibitor BRAF... VEGFR, PDGFR, c-kit... Hepatocellular carci…
CTLA-4
Also called CD152... Surface of T cells ... Down regulates... Fusion w…
Ipilimumab
CTLA-4 antagonist in metastatic melanoma
70 terms
Oncology
Cancer-free for 5 years
Treatment types
Toxicities of chemo drugs
Monitoring/treating myelosuppression
"Cured"... Unlikely that the cancer will recur
-Primary tx: surgery if cancer is resectable ... -Neoadjuvant th…
-Due to damaging effects on non-cancerous, rapidly dividing c…
-Almost all chemo drugs, EXCEPT: asparaginase, bleomycin, vin…
Cancer-free for 5 years
"Cured"... Unlikely that the cancer will recur
Treatment types
-Primary tx: surgery if cancer is resectable ... -Neoadjuvant th…
28 terms
Oncology
What cell cycle phase do all antimetab…
Azathioprine, 6-mercaptopurine (ANTIME…
Cladribine (ANTIMETABOLITE)
Cytarabine (ANTIMETABOLITE)
S-phase
-mechanism: Purine (thiol) analogs... de novo purine synthesis.…
-mechanism: Purine analog---> multiple mechanisms (eg, inhibi…
-mechanism: Pyrimidine analog ---> inhibition of DNA polymera…
What cell cycle phase do all antimetab…
S-phase
Azathioprine, 6-mercaptopurine (ANTIME…
-mechanism: Purine (thiol) analogs... de novo purine synthesis.…
153 terms
oncology
3-5 year old child... Pancytopenia (bleed…
30+ year old... Pancytopenia (bleeding, f…
30-50 years old... WBC count greater than…
50+ year old... Male gender... lymphadenopat…
Acute Lymphoblastic Leukemia
AML
CML
CLL
3-5 year old child... Pancytopenia (bleed…
Acute Lymphoblastic Leukemia
30+ year old... Pancytopenia (bleeding, f…
AML
Oncology
Cancer
Carcinogen
Oncologist
Oncology
Uncontrolled division of abnormal body cells that for. Abnorm…
Cancer causing substance
Physical specializing in cancer
Study of cancer
Cancer
Uncontrolled division of abnormal body cells that for. Abnorm…
Carcinogen
Cancer causing substance
30 terms
ONCOLOGY
BETATRON
CARCINOGEN
CARCIN/O
-GEN
MEGA VOLTAGE MACHINE USED IN ADMINISTERING EXTERNAL RADIATION…
A CANCER CAUSING AGENT
CANCER
FORMATION
BETATRON
MEGA VOLTAGE MACHINE USED IN ADMINISTERING EXTERNAL RADIATION…
CARCINOGEN
A CANCER CAUSING AGENT
Oncology
Ifosfamide
Pegfilgrastim
Etoposide
Carboplatin
...
...
...
...
Ifosfamide
...
Pegfilgrastim
...
9 terms
Oncology
General Considerations
General Cancer Manifestations
Bone Marrow/Stem Cell Transplantation
Leukemias
Cancer can be caused by genetics or environmental factors (to…
Nausea and vomiting, fatigue, alopecia (should grow back in 3…
Becoming more frequent (it can cure the cancer but the illnes…
The most common childhood cancer (seen in boys more than girl…
General Considerations
Cancer can be caused by genetics or environmental factors (to…
General Cancer Manifestations
Nausea and vomiting, fatigue, alopecia (should grow back in 3…
15 terms
oncology
oncology
cachexia
early signs of cancer
tissue of origin classification & like…
study of tumors
wasting away
abnormal swelling, sores that don't heal, weight loss, loss o…
carcinomas: epithelial tissue, spread through lymphatic syste…
oncology
study of tumors
cachexia
wasting away
164 terms
oncology
Overview of Cancer ... -Second leading c…
lifestyles that cause cancer (5)
PATHOPHYSIOLOGY OF CANCER:... 1. a tumor…
CARCINOGENS/FACTORS PROMOTING CANCER: 10
...
smoking, ... sun exposure, ... exposure to chemicals you may work w…
1. carcinoma... 2. cancer
chemical... radiation... genetic... coping... environment/social... age ... hor…
Overview of Cancer ... -Second leading c…
...
lifestyles that cause cancer (5)
smoking, ... sun exposure, ... exposure to chemicals you may work w…
Oncology
oncology
tumor clinical signs
carcinomas
sarcomas
the study of cancer
-destroys tissue and impairing normal tissue function... -causes…
-arise from epithelial tissue... -spread through both lymphatic…
-arise from connective tissue... -spread through the bloodstream…
oncology
the study of cancer
tumor clinical signs
-destroys tissue and impairing normal tissue function... -causes…
Oncology
ana-
-blast
carcin/o
chem/o
not, without
embryonic stage of development
cancer
pertaining to chemical; drug
ana-
not, without
-blast
embryonic stage of development
106 terms
Oncology
Stats about CA - How many new cases pe…
Stats about CA - How many pts will die…
Stats about CA - How many pts die from…
Stats about CA - How many people have…
> 9.7 million new cases
- 6.7 million
- 1700
- 20.4 million
Stats about CA - How many new cases pe…
> 9.7 million new cases
Stats about CA - How many pts will die…
- 6.7 million
18 terms
Oncology
cac/o
follicul/o
medull/o
mut/a
bad
samll grandular sacs
soft, inner part
genetic change
cac/o
bad
follicul/o
samll grandular sacs
13 terms
Oncology
Tumor
Neoplasia
Hypertrophy
Hyperplasia
Swelling
New growth
Increase in organ size or mass due to increased size of cells
Increase in organ size or mass due to increased number of cells
Tumor
Swelling
Neoplasia
New growth
14 terms
Oncology
Adeno-
Chondro-
Erythro-
Hemanglo-
gland
cartilage
red blood cell
blood vessels
Adeno-
gland
Chondro-
cartilage
33 terms
oncology
<35 year old male... pain +/- relief with…
Why is osteoid osteoma painful?
well defined radiolucent nidus with su…
most common site for osteoid osteoma
Osteoid osteoma
Elevated Prostaglandin E2 levels in Nidus
osteoid osteoma
proximal femur
<35 year old male... pain +/- relief with…
Osteoid osteoma
Why is osteoid osteoma painful?
Elevated Prostaglandin E2 levels in Nidus
17 terms
Oncology
Biotherap
Surgical Oncology
Neutropenia
Cytokines
treatment that uses substance made from living organism (natu…
specialized are of oncology that encourage surgeon in the cur…
low level of neutrophils, a type of white blood cell. Neutrop…
cell signaling molecules that aid cell to cell communication…
Biotherap
treatment that uses substance made from living organism (natu…
Surgical Oncology
specialized are of oncology that encourage surgeon in the cur…
37 terms
Oncology
Alopecia
Carcinoma
Adenocarcinomas
Sarcoma
the loss of hair
a malignant tumor composed of epithelial cells that metastasize
cancer of the linings of the organs or cavities
a malignant tumor of connective tissue (e.g. muscle, bone, or…
Alopecia
the loss of hair
Carcinoma
a malignant tumor composed of epithelial cells that metastasize
31 terms
Oncology
Intrinsic factors v. Extrensic
Benign cells v. Malignant cells
3 stages of transformation
What enhances cell growth?
Intrinsic: internal, immutable... -Immune system: tumors alter a…
Benign:... -Defined borders... -Same appearance: size, shape... -Has a…
Transformation: transition from benign to malignant... 1. Initia…
Blood supply
Intrinsic factors v. Extrensic
Intrinsic: internal, immutable... -Immune system: tumors alter a…
Benign cells v. Malignant cells
Benign:... -Defined borders... -Same appearance: size, shape... -Has a…
Oncology
Oncology
Hematologic cancers
Non-hematologic cancers
Tumors and Cancers
The study of tumors and cancer
originate in the bone marrow, lymphatic system and other cell…
originate in solid tissues
Characterized by abnormal cell growth and division.
Oncology
The study of tumors and cancer
Hematologic cancers
originate in the bone marrow, lymphatic system and other cell…
87 terms
Oncology
cancer
1/2
1/3
1/3
abnormal division & reproduction of cells, can spread through…
men lifetime risk of cancer
women lifetime risk of cancer
fraction of cancers related to lifestyle and diet
cancer
abnormal division & reproduction of cells, can spread through…
1/2
men lifetime risk of cancer
Oncology
Hypertrophy
Main immunological mediators of acute…
Main immunological mediators of chroni…
Atrophy
Cells too big
Neutrophils, macrophages
Lymphocytes, plasma cells, macrophages
Shrinkage of cell size
Hypertrophy
Cells too big
Main immunological mediators of acute…
Neutrophils, macrophages
18 terms
Oncology
Xeloda
Ellence
Avastin
Camptosar
capecitabine
epirubicin
bevacizumab
irinotecan
Xeloda
capecitabine
Ellence
epirubicin
14 terms
Oncology
Leukine
6-MP
Arimidex
Novaldex
sargramostin
mercaptopurine
anastrozole
tamoxifen
Leukine
sargramostin
6-MP
mercaptopurine
Oncology
adjuvant
adjuvant therapy
anaplasia
antimetabolite
a substance, especially a drug, added to a prescription to as…
treatment of a disease with a substance, especially a drug th…
change in the structure and orientation of cells characterize…
class of antineoplastic drugs used to treat cancer; most effe…
adjuvant
a substance, especially a drug, added to a prescription to as…
adjuvant therapy
treatment of a disease with a substance, especially a drug th…
ONCOLOGY
Cell-cycle Non-specific
Cell Cycle specific agents
Alkylating agents
Alkylating agents MOA
Alkylating agents... Platinum agents ... Anthracyclines
Vinca Alkaloids ... Taxanes ... topoisomerase I inhibitors ... topoiso…
Cyclophosphamides (cytoxan)... Ifosfamide(ifex)
agents work by cross-linking DNA strands and inhibiting prote…
Cell-cycle Non-specific
Alkylating agents... Platinum agents ... Anthracyclines
Cell Cycle specific agents
Vinca Alkaloids ... Taxanes ... topoisomerase I inhibitors ... topoiso…
6 terms
Oncology
Cancer
Potential Etiologies
Cancer Staging
Imaging
#3 cause of death in the US
Food... -fluorinated water ... -cooked meats ... -artificial sweetener…
-staging describes the extent or severity of a person's cance…
- X-Ray Imaging... - CT Scans... - Nuclear Imaging (PET and SPECT)…
Cancer
#3 cause of death in the US
Potential Etiologies
Food... -fluorinated water ... -cooked meats ... -artificial sweetener…
Oncology
Filgrastim
Pegfligrastim
Sargramostim
Granisetron
Neupogen, Zarxio
Neulasta
Leukine (limited to use in stem cell transplantation
Kytril
Filgrastim
Neupogen, Zarxio
Pegfligrastim
Neulasta
73 terms
Oncology
busulfan
cyclophosphamide
ifosfamide
carboplatin
Myleran
Cytoxan
Ifex
Paraplatin
busulfan
Myleran
cyclophosphamide
Cytoxan
Oncology
stage
grade
TNM staging system for malignant tumors
staging indicators with TNM criteria
stage I, stage IA... stage IV, stage IVB
grade 1 ... grade 2... grade 3... grade 4
NO SPACES OR COMMAS... T=tumor size or involvement... TX primary tu…
grade Gx, G1, G2, G3, G4... host performance H0, H1, H2, H3, H4…
stage
stage I, stage IA... stage IV, stage IVB
grade
grade 1 ... grade 2... grade 3... grade 4
Oncology
Adrenal
Anal
Bile Duct
Bladder
l
...
...
...
Adrenal
l
Anal
...
Oncology
cancer
malignant tumor
benign tunor
metastasis
abnormal growth of cells that have no use to the body
non-encapsulated abnormal growth of cells... not differentiated…
encapsulated abnormal growth of cells... does not spread
the spread of cancerous cells.
cancer
abnormal growth of cells that have no use to the body
malignant tumor
non-encapsulated abnormal growth of cells... not differentiated…
10 terms
Oncology
Avastatin
Revlimid
Rituxan
Herceptin
Bevacizumab
Lenalidomide
Rituximab
Trastuzumab
Avastatin
Bevacizumab
Revlimid
Lenalidomide
69 terms
Oncology
Oncology
Benign
Malignant
Adenocarcinoma
The study of tumors
Noncancerous
Cancerous
Cancerous tumor of glandular tissue
Oncology
The study of tumors
Benign
Noncancerous
26 terms
Oncology
Oncology
Neoplasm
Malignant neoplasms
Benign neoplasms
study and treatment of tumors
gradual increase in the number of dividing cells creates a gr…
cells that invade neighboring tissues, enter blood vessels, a…
tumor cells grow only locally and cannot spread by invasion…
Oncology
study and treatment of tumors
Neoplasm
gradual increase in the number of dividing cells creates a gr…
Oncology
adenocarcinoma
adenoma
carcinoma (CA)
chloroma
...
...
...
...
adenocarcinoma
...
adenoma
...
13 terms
Oncology
General Signs and Symptoms
Epithelium
Pigmented Cells
Connective Tissues
CAUTION... Change in bowel or bladder routine... A sore that will…
Carcinoma, adenocarcinoma (glandular tissue)... - skin, lines i…
Malignant melanoma... - moles
Sarcoma, fibrosarcoma, liposarcoma, chondrosarcoma, osteosarc…
General Signs and Symptoms
CAUTION... Change in bowel or bladder routine... A sore that will…
Epithelium
Carcinoma, adenocarcinoma (glandular tissue)... - skin, lines i…
41 terms
Oncology
leukemia
lymphoma
leukemoid rxn
hodgkin's
lymphoid or myeloid neoplasm w/ widespread involvement of BM…
discrete tumor mass arising from LNs
-acute inflamm response to infection... -inc WBC ct w/ inc neutr…
-localized, single group of nodes, extranodal rare... -contiguou…
leukemia
lymphoid or myeloid neoplasm w/ widespread involvement of BM…
lymphoma
discrete tumor mass arising from LNs
44 terms
Oncology
Acute Myelogenous Leukemia
RFs AML
AML SS
AML dx
Cancer of myeloid blood cells... Rapid growth of abnormal/immatu…
Increased age... Previous chemotherapy agents... Exposure to radiat…
Fatigue, lethargy (preceeds diagnosis)... SOB... Easy bruising, Unu…
Bone marrow aspirate and biopsy
Acute Myelogenous Leukemia
Cancer of myeloid blood cells... Rapid growth of abnormal/immatu…
RFs AML
Increased age... Previous chemotherapy agents... Exposure to radiat…
8 terms
Oncology
Life span considerations
Cultural considerations
Carcinogenesis
Carcinogens
Incidence of cancer increases with age, most commonly prostat…
Incidence of cancer is higher among African Americans, death…
The process by which normal cells are transformed into cancer…
Substances known to increase risk for cancer (smoking, high f…
Life span considerations
Incidence of cancer increases with age, most commonly prostat…
Cultural considerations
Incidence of cancer is higher among African Americans, death…
Oncology
Kawasaki disease
Most common childhood cancers
Immundodificency disease that may pred…
Presenting features of childhood cancer
-Dx: fever >5 days + >4 of following: bilateral nonexudative…
-leukemia, brain tumors, lymphoma, neuroblastoma, soft tissue…
-Wiskott-Aldrich syndorme: characterized by B and T cell dysf…
-persistent fever: leukemia, lymphoma, and other cancers ... -pa…
Kawasaki disease
-Dx: fever >5 days + >4 of following: bilateral nonexudative…
Most common childhood cancers
-leukemia, brain tumors, lymphoma, neuroblastoma, soft tissue…
Oncology
Risk factors
CAUTION
Primary prevention
Secondary prevention
💠
C... A... U... T... I... O... N
...
...
Risk factors
💠
CAUTION
C... A... U... T... I... O... N
16 terms
Oncology
Adenocarcinoma
Benign
Biopsy
Carcinoma
...
...
...
...
Adenocarcinoma
...
Benign
...
96 terms
Oncology
Zofran
Zuplenz
Kytril
Sancuso
ondansetron
ondansetron film
granisetron
granisetron patch
Zofran
ondansetron
Zuplenz
ondansetron film
Oncology
Alkylating Agents... stops cell DNA repli…
Alkylator-like agents... stops cell repli…
Nitrosureas... similar to alkylating agen…
Chemo Protective drugs (adjunct agents…
Cyclophosphamide (Cytoxan)... Tx: Brst, ovarian, lung, mult myel…
Cisplantin (Platinol)... Tx: Bladder, testicular, ovarian... SE: Ne…
Lomustine (po), carmustine (IV)... Txs: Brain tumors ... Side effec…
Amifostine (Ethyol) ... Actions: Cytoprotective ◦ **Protects he…
Alkylating Agents... stops cell DNA repli…
Cyclophosphamide (Cytoxan)... Tx: Brst, ovarian, lung, mult myel…
Alkylator-like agents... stops cell repli…
Cisplantin (Platinol)... Tx: Bladder, testicular, ovarian... SE: Ne…
Oncology
Sarcomas are cancers that begin in the…
In the TNM classification (staging) sy…
One monoclonal antibody drug can be us…
The most curable form of cancer is Hod…
False- Sarcomas are cancers that begin in connective or suppo…
True- This staging system is based on the extent or severity…
False- Each monoclonal antibody recognizes only one particula…
True- Hodgkin disease is a malignancy of the of lymph tissue…
Sarcomas are cancers that begin in the…
False- Sarcomas are cancers that begin in connective or suppo…
In the TNM classification (staging) sy…
True- This staging system is based on the extent or severity…
Oncology
Cholangioma Liver Cancers
Bladder Cancer
Burkitt's Lymphoma
Adult T Cell Lymphoma
Opisthorchid trematodes
Schistosome trematodes
EBV & Plasmodium falciparum
T lymphotropic virus
Cholangioma Liver Cancers
Opisthorchid trematodes
Bladder Cancer
Schistosome trematodes
81 terms
Oncology
cancer
cancer can be classified as
What are the two types of cancers
hematologic malignancies
refers to a class of disease... cancer starts with one abnormal…
tissue or blood cell where it starts... the type
solid tumors- arise from specific tissues... sarcomas- connecti…
blood cells... original from blood or lymphatic cells... -leukemia…
cancer
refers to a class of disease... cancer starts with one abnormal…
cancer can be classified as
tissue or blood cell where it starts... the type
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