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Study sets matching "overdose"

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Study sets matching "overdose"

10 terms
Overdose
How much aspirin causes severe toxicity?
Salicylate tablets can form [blank], p…
What is the most toxic form of salicyl…
What acid base disturbance does salicy…
over 150 mg/kg
Bezoars
Oil of Wintergreen
Respiratory alkalosis and a metabolic acidosis
How much aspirin causes severe toxicity?
over 150 mg/kg
Salicylate tablets can form [blank], p…
Bezoars
Overdose
Atropine
Ketorolac (Toradol)
NSAIDS cause
Midazolam (Versed)
anticholinergic, Treats pesticide poisoning
NSAID; 60 MG IM/30 MG IV
GI distress, platelet inhibitors, nephrotoxic
Benzodiazepine; 1-2 MG; causes unpredictable effects in elderly
Atropine
anticholinergic, Treats pesticide poisoning
Ketorolac (Toradol)
NSAID; 60 MG IM/30 MG IV
25 terms
Overdose
Alcohol Intoxication
Alcohol withdrawal
Opioids Intoxication
Opioid Withdrawal
Disinhibition, emotional lability, slurred speech, ataxia, ag…
Tremor, tachycardia, HTN, malaise, Nausea, seizures, DTs, agi…
Morphine, tramadol, oxycodone, methadone, heroin... Dec Breath s…
Morphine, tramadol, oxycodone, methadone, heroin... NOT life-thr…
Alcohol Intoxication
Disinhibition, emotional lability, slurred speech, ataxia, ag…
Alcohol withdrawal
Tremor, tachycardia, HTN, malaise, Nausea, seizures, DTs, agi…
10 terms
overdose
Anxiety, mydriasis, restless/tremor, s…
sedation/drowsiness, fatigue, hypersom…
perception distortion, hallucination,…
stimulates release of catecholamines
what are the signs/symptoms of CNS stimulants and examples
what are the signs/symptoms of CNS depressants and examples
what are the signs/symptoms of CNS psychomimetics and examples
what is the MOA of amphetamines
Anxiety, mydriasis, restless/tremor, s…
what are the signs/symptoms of CNS stimulants and examples
sedation/drowsiness, fatigue, hypersom…
what are the signs/symptoms of CNS depressants and examples
23 terms
Overdose
Paracetamol
Salicylate
Salicylate (severe)
Opioid
N-acetylcysteine
uirnary alkalinization
haemodialysis
naloxone
Paracetamol
N-acetylcysteine
Salicylate
uirnary alkalinization
43 terms
overdose
seizures tx w
withdrawal tx w
hypotension tx w
if GCS less than 9
benzos
tx with agent withdrawing from
fluids and pressors if severe
needs intubation
seizures tx w
benzos
withdrawal tx w
tx with agent withdrawing from
13 terms
Overdose
Sedation, lethargy, slurred speech, at…
Agitation, tachycardia, urinary retent…
Haematemesis
Methanol
BZD
Anticholinergic toxidrome: antihistamines, 1st gen antipsycho…
NSAID (aspirin, etc.), Iron
Rx: Ethanol
Sedation, lethargy, slurred speech, at…
BZD
Agitation, tachycardia, urinary retent…
Anticholinergic toxidrome: antihistamines, 1st gen antipsycho…
6 terms
Overdose
Narcotics
Stimulants
Hallucinogens
Cannabis
Shallow breathing, clammy skin, convulsions, coma, possible d…
Agitation, increased temperature, hallucinations, convulsions…
Increased temperature, inability to feel pain or make direct…
Fatigue, paranoia
Narcotics
Shallow breathing, clammy skin, convulsions, coma, possible d…
Stimulants
Agitation, increased temperature, hallucinations, convulsions…
5 terms
Overdose
Calcium Chloride
Glucagon
Sodium Bicarbonate Na HCO3
Flumazenil (romazicon)
Calcium Channel blocker OD ... adult: 1g SIVP... peds: 20mg/kg SIVP
Beta Blocker OD ... adult: 1mg IV X3... peds:... <25kg: 0.5mg IM X3…
Tricyclic / aspirin / benadryl / cocain OD... adult: 1mEq/kg IV…
Benzodiazepine OD ... adult: 0.2mg IV... peds: <1YO 0.01mg/kg IV…
Calcium Chloride
Calcium Channel blocker OD ... adult: 1g SIVP... peds: 20mg/kg SIVP
Glucagon
Beta Blocker OD ... adult: 1mg IV X3... peds:... <25kg: 0.5mg IM X3…
25 terms
Overdose
TDAP
VARIVAX
GARDASIL
INFLUENZA
REFRIGERATED
FROZEN
REFIGERATED
REFRIGERATED
TDAP
REFRIGERATED
VARIVAX
FROZEN
10 terms
OVERDOSE
Heparin
Warfarin
Acetaminophen
Opioids
Protamine Sulfate
Vitamin K
Mucomyst
Naloxone (Narcan)
Heparin
Protamine Sulfate
Warfarin
Vitamin K
9 terms
Overdose
Hyperthermia
Hypothermia
Tachycardia
Bradycardia
anticholinergics
barbiturates, ethanol
anticholinergics, sympathomimetics
Beta Blockers, cholinergics which are organophosphates
Hyperthermia
anticholinergics
Hypothermia
barbiturates, ethanol
10 terms
Overdose
mercury poisoning
Cyanide poisioning
Beta blocker over dose
Disulfram over dose
succimer
thiosulfate and amyl nitrate
glucagon
fomepizole
mercury poisoning
succimer
Cyanide poisioning
thiosulfate and amyl nitrate
22 terms
overdose
Tetrahydrocannabinol
Amotivational Syndrome
Depressant
Stimulant
a crystalline compound that is the main active ingredient of…
psychological condition associated with diminished inspiratio…
a drug reducing functional or nervous activity
a substance that raises levels of physiological or nervous ac…
Tetrahydrocannabinol
a crystalline compound that is the main active ingredient of…
Amotivational Syndrome
psychological condition associated with diminished inspiratio…
12 terms
Overdose
(Noah Enters)
Yeah, it's nice to meet you too.
Good, I guess.
It's hard to put these feelings into w…
Noah, it's so nice to meet you finally
Well how are you?
It's just crazy to think that I have a brother. Never in a mi…
This is just so much to take in. It's just all of my history,…
(Noah Enters)
Noah, it's so nice to meet you finally
Yeah, it's nice to meet you too.
Well how are you?
13 terms
Overdose
What did they O/D w/? ... tinnitus, hyper…
What did they O/D w/?... normal pH... low CO…
DOC to prevent seizures from TCA O/D
DOC for aspirin O/D
Aspirin
Aspirin
benzos
alk the urine to inc secretion w/ bicarb
What did they O/D w/? ... tinnitus, hyper…
Aspirin
What did they O/D w/?... normal pH... low CO…
Aspirin
18 terms
Overdose
ETOH lvls
clinical presentation
hypoglycemia ETOH
diagnostic
serum alcohol lvls ... * 200 mg/dl (mild intoxication... * >500 mg/…
CNS = sluggish reflexes, slurred speech, uncoordinated muscle…
hypogllycemia may induce unconsciousness as alcohol ingestion…
sesrum ethanol... BUN/Cr (elevated d/t renal dysfunction... Liver…
ETOH lvls
serum alcohol lvls ... * 200 mg/dl (mild intoxication... * >500 mg/…
clinical presentation
CNS = sluggish reflexes, slurred speech, uncoordinated muscle…
133 terms
OVERDOSE
decisive action
mutual funds
bonds
properly
zdecydowane działanie
fundusze inwestycyjne
obligacje / papiery wartościowe
odpowiednio,właściwie
decisive action
zdecydowane działanie
mutual funds
fundusze inwestycyjne
9 terms
Overdose
Opioid overdose symptoms
Opioid overdose treatment
Any overdose - what to consider in the…
Alternative name for heroin?
Coma ... Decreased respiratory rate... Pinpoint pupils ... Hypotension…
0.8mg of NALOXONE (Opioid Antagonist) every 2-3 minutes... May b…
Activated charcoal
Diamorphine
Opioid overdose symptoms
Coma ... Decreased respiratory rate... Pinpoint pupils ... Hypotension…
Opioid overdose treatment
0.8mg of NALOXONE (Opioid Antagonist) every 2-3 minutes... May b…
Overdose
ASA effects
Digoxin OD
What can cause Digoxin toxicity
Ethylene Glycol OD
Stimulates brainstem - hyperventilation, damages lungs - ards…
GI disturbance (n,v,d), hyperkalemia (damages Na/K ATPase), y…
Hypokalemia
Anion gap metabolic acidosis, Renal insufficiency, hypocalcem…
ASA effects
Stimulates brainstem - hyperventilation, damages lungs - ards…
Digoxin OD
GI disturbance (n,v,d), hyperkalemia (damages Na/K ATPase), y…
8 terms
Overdose
Features of tricyclic overdose?
Features of an aspirin overdose?
Investigation results in TCA overdose?
Investigation results in aspirin overd…
Pupils dilated, blurred vision, seizures, decreased GCS, arry…
Increased RR, vomiting, tinnitus, vertigo, sweating
Acidosis, prolonged PR, QRS and QTc heart block, ventricular…
Initially respiratory alkalosis followed by metabolic acidosi…
Features of tricyclic overdose?
Pupils dilated, blurred vision, seizures, decreased GCS, arry…
Features of an aspirin overdose?
Increased RR, vomiting, tinnitus, vertigo, sweating
37 terms
Overdose
Did he/she/you take some pills/capsules?
What kind of pills did you/he/she take?
How many did you/he/she take?
What colour were they?
¿Tomó pastillas/píldoras/cápsulas? ... ¿Pildoreó?
¿Qué tipo de píldoras tomó?... ¿Qué tipo de pastillas ingirió?
¿Cuántas tomó?
¿De qué color(es) eran?
Did he/she/you take some pills/capsules?
¿Tomó pastillas/píldoras/cápsulas? ... ¿Pildoreó?
What kind of pills did you/he/she take?
¿Qué tipo de píldoras tomó?... ¿Qué tipo de pastillas ingirió?
15 terms
Overdosing
Theophylline od symp
theophylline od rx
iron od symp
beta blocker od symp
seizures... tachyarrhythmias
activated charcoal to prevent further GI absorption... seizures…
melena, hematemesis
bradycardia, hypoglycemia, hypotension
Theophylline od symp
seizures... tachyarrhythmias
theophylline od rx
activated charcoal to prevent further GI absorption... seizures…
22 terms
Overdoses
Paracetamol <1hr
Paracetamol
Warfarin
Aspirin (salicylate)
Activated charcoal
N-acetylcysteine
Vitamin K, Prothrombin complex
Haemodialysis
Paracetamol <1hr
Activated charcoal
Paracetamol
N-acetylcysteine
26 terms
Overdoses
How do you treat overdose on weak bases?
Tetrodotoxin
Ciguatoxin
Scombroid Toxin
Acidify urine, give ammonium chloride... Amphetamines, TCAs
Pufferfish toxin - "new japanese restaurant"... Binds fast volt…
Toxin in "reef fish" such as barracude, snapper, moray eel... O…
Histamine found in spoiled dark-meat fish such as tuna, mahi-…
How do you treat overdose on weak bases?
Acidify urine, give ammonium chloride... Amphetamines, TCAs
Tetrodotoxin
Pufferfish toxin - "new japanese restaurant"... Binds fast volt…
24 terms
Overdoses
Acetaminophen Route of exposure
Acetaminophen Toxic dose Acute ingestion
Acetaminophen Mechanism of Toxicity
Acetaminophen Toxic dose Chronic inges…
Oral
Doses greater than 7.5 g or 140 mg/kg
Metabolism is primarily hepatic and can cause hepatotoxicity…
> 4 g per day especially in chronic alcoholics
Acetaminophen Route of exposure
Oral
Acetaminophen Toxic dose Acute ingestion
Doses greater than 7.5 g or 140 mg/kg
8 terms
Overdoses
TCAs
APAP
Dogoxin
Warfarin
Bicarb (signs: Tonic-colonic, Cardio, Anticholinergic)
N-acetylcysteine (NAC) mucomist use Rumack nomogram
Digibind®
Vitamin K
TCAs
Bicarb (signs: Tonic-colonic, Cardio, Anticholinergic)
APAP
N-acetylcysteine (NAC) mucomist use Rumack nomogram
52 terms
Overdosing
What may be a fatal dose of paracetamol?
In the average 70kg man, what dose may…
which patients are paracetamol overdos…
why are these patients more likely to…
150mg/kg
10g
alcoholics... epileptics ... enzyme inducing drugs (CP450)
more susceptible to developing hepatotoxicity and nephrotoxic…
What may be a fatal dose of paracetamol?
150mg/kg
In the average 70kg man, what dose may…
10g
21 terms
Overdose Points
Induction of Emesis- REMEMBER THIS!!
Cathartics-
Hemoperfusion
APAP Overdoses Remember this!!!
Ipecac is derived from the ipecac root which is actually po…
These make you push the poison/drug out the other end of your…
blood is being run through a filter with an absorbent agent i…
Serum acetaminophen levels at <4 hours since the ingestion is…
Induction of Emesis- REMEMBER THIS!!
Ipecac is derived from the ipecac root which is actually po…
Cathartics-
These make you push the poison/drug out the other end of your…
22 terms
Overdose & Poisoning
What is the most common form of poison…
How is paracetamol usually metabolised…
How is paracetamol metabolised in over…
What predisposes someone to hepatotoxi…
Paracetamol
- Conjugated with glucuronide and sulphate... - Small amount met…
- Large amounts metabolised by oxidation due to saturation of…
Considered high risk for treatment purposes:... - Pre-existing l…
What is the most common form of poison…
Paracetamol
How is paracetamol usually metabolised…
- Conjugated with glucuronide and sulphate... - Small amount met…
35 terms
Overdose vocabulary
real estate
sober
hangover
borrow
nieruchomości
trzeźwy
kac
pożyczać (od kogoś)
real estate
nieruchomości
sober
trzeźwy
35 terms
Overdose vocabulary
real estate
sober
hangover
borrow
nieruchomości
trzeźwy
kac
pożyczać (od kogoś)
real estate
nieruchomości
sober
trzeźwy
37 terms
Antidotes for Overdose
Acetaminophen overdose
Acetylcysteine MOA
Acetylcysteine dose
Mucomyst, Acetadote are trade names fo…
Acetylcysteine
MOA: thought to reverse APAP toxicity by providing substrate…
Dose: oral- 140 mg/Kg followed by 17 doses of 70 mg/Kg Q4h; r…
Acetylcysteine
Acetaminophen overdose
Acetylcysteine
Acetylcysteine MOA
MOA: thought to reverse APAP toxicity by providing substrate…
14 terms
Overdose vocabulary
real estate
sober
hangover
borrow
nieruchomości
trzeźwy
kac
pożyczać (od kogoś)
real estate
nieruchomości
sober
trzeźwy
35 terms
Overdose vocabulary
real estate
sober
hangover
borrow
nieruchomości
trzeźwy
kac
pożyczać (od kogoś)
real estate
nieruchomości
sober
trzeźwy
35 terms
Overdose vocabulary
real estate
sober
hangover
borrow
nieruchomości
trzeźwy
kac
pożyczać (od kogoś)
real estate
nieruchomości
sober
trzeźwy
24 terms
Overdose vocabulary
collapse
Dice
Cover
Despite
upadać, zawalić się , runąć; upadek, krach
Kostka do gry
Przykryć nakryc
Wbrew czemuś
collapse
upadać, zawalić się , runąć; upadek, krach
Dice
Kostka do gry
35 terms
Overdose vocabulary
real estate
sober
hangover
borrow
nieruchomości
trzeźwy
kac
pożyczać (od kogoś)
real estate
nieruchomości
sober
trzeźwy
21 terms
Overdose - Antidote
Tox: Acetaminophen
Tox: Salicylates
Tox: Amphetamines (basic)
Tox: Anticholinesterases, organophosph…
Antidote: N-acetylcysteine
Antidote: NaHCO3 (alkalinize urine), dialysis
Antidote: NH4Cl (acidify urine)
Antidote: Atropine, pralidoxime
Tox: Acetaminophen
Antidote: N-acetylcysteine
Tox: Salicylates
Antidote: NaHCO3 (alkalinize urine), dialysis
35 terms
overdose elements
hydrogen
helium
lithium
Beryllium
H, 1, gas
He, 2, gas
Li, 3, solid
Be, 4, solid
hydrogen
H, 1, gas
helium
He, 2, gas
61 terms
Overdose_M
S/S of APAP overdose
Toxic Dose of APAP
Treatment for APAP overdose
Treatment dose of N-Acetyl Cysteine (o…
Sweating, lethargy, RUQ pain, pancreatitis, LFTs elevated, ja…
7.5 - 15 g
N-Acetyl Cysteine
140 mg/kg loading dose; 70 mg/kg q 4 hours x 17 doses
S/S of APAP overdose
Sweating, lethargy, RUQ pain, pancreatitis, LFTs elevated, ja…
Toxic Dose of APAP
7.5 - 15 g
22 terms
antidotes/overdose
Give treatment for acetaminophen overd…
Give treatment for salicylates overdose.
give treatment for amphetamines overdose
Give treatment for antimuscarinic and…
N-Acetylcysteine (replenishes glutathione).
NaHCO3 (alkalinize urine)
NH4Cl (acidify urine)
Phygostigmine and control the hyperhermia.
Give treatment for acetaminophen overd…
N-Acetylcysteine (replenishes glutathione).
Give treatment for salicylates overdose.
NaHCO3 (alkalinize urine)
Drug overdose
Heparin
Warfarin
Clopidogrel (plavix)
Epogen
Protamine sulfate
Vitamin K
Platelet transfusions to prevent hemorrhage
May lead to polycthemia corrected with phlebotomy
Heparin
Protamine sulfate
Warfarin
Vitamin K
23 terms
Overdose/Antidotes_C
In descending order of frequency what…
In reports by poison control centers d…
Antidote Nacetylcysteine indication
Antidote activated charcoal indication
Carbon monoxide... Ethanol... Sedatives... Opioids... Propoxyphene... Cyclic…
Analgesics... Antidepressants... Stimulants... Sedatives/hypnotics... Car…
Acetaminophen
Adsorbent
In descending order of frequency what…
Carbon monoxide... Ethanol... Sedatives... Opioids... Propoxyphene... Cyclic…
In reports by poison control centers d…
Analgesics... Antidepressants... Stimulants... Sedatives/hypnotics... Car…
27 terms
Toxicology & Overdose
Ipecac Syrup
Ipecac Syrup Contraindications
Activated Charcoal
Activated Charcoal Dose/Directions
induces vomiting
• lacks gag reflux... • lethargic, comatose, convulsing... • alread…
reduces toxin absorption by chemically adsorbing thee drug
25-100mg 1-2 hours after ingestion, multiple may be considered
Ipecac Syrup
induces vomiting
Ipecac Syrup Contraindications
• lacks gag reflux... • lethargic, comatose, convulsing... • alread…
58 terms
Overdose treatment
treat benzo overdose
miosis (constriction of pupils) can be…
Dilation of the pupils (mydriasis) can…
odor like bitter almonds can be caused…
flumazenil unless history of seizure disorder or TCA overdose
opioids, clonidine, phenothiazines, and cholinesterase inhibi…
amphetamines, cocaine, LSD, atropine and other anticholinergi…
cyanide poisoning
treat benzo overdose
flumazenil unless history of seizure disorder or TCA overdose
miosis (constriction of pupils) can be…
opioids, clonidine, phenothiazines, and cholinesterase inhibi…
7 terms
Overdose treatment
Carbon monoxide
paraquat
aspirin
amphetamine
100% O2 of hyprbaric oxygen (if carboxyhaemoglobin >40%)
activated charcoal
haemodialysis
supportive (esp. fluids)
Carbon monoxide
100% O2 of hyprbaric oxygen (if carboxyhaemoglobin >40%)
paraquat
activated charcoal
26 terms
Overdose/Antidotes
Flumazenil... Naloxone... Dextrose... Thiamine
Decontaminate
Deferoxamine
Digibind... Digoxin antibodies
Coma cocktail
Induce vomiting (Ipecac)... Whole bowel irrigation... Gastric lavag…
Iron Salts
Digoxin... Cardiac related glycosides
Flumazenil... Naloxone... Dextrose... Thiamine
Coma cocktail
Decontaminate
Induce vomiting (Ipecac)... Whole bowel irrigation... Gastric lavag…
40 terms
Opioid Overdose
Common drug related causes of death
Risk factors for opioid overdose
DOA of IR vs ER oxycodone
_________ accounts for 1/3 of deaths f…
Opoid overdose: One of the most frequent causes of drug-relat…
Depression, Anxiety, Stress... Addiction to other substances (ni…
IR: 3-6 hours ... ER: 8-12 hours
methadone
Common drug related causes of death
Opoid overdose: One of the most frequent causes of drug-relat…
Risk factors for opioid overdose
Depression, Anxiety, Stress... Addiction to other substances (ni…
21 terms
drug overdose
anticholinergic toxidrome
cholinergic toxidrome
opioid toxidrome
sympathamimetic toxidrome
s/s: delirium; dry, flushed skin; dilated pupils; inc. temp,…
s/s: excessive salivation, lacrimation, urination, diarrhea,…
s/s: CNS depression, respiratory depression, constricted pupi…
s/s: agitation, tachycardia, hypertension, seizures, metaboli…
anticholinergic toxidrome
s/s: delirium; dry, flushed skin; dilated pupils; inc. temp,…
cholinergic toxidrome
s/s: excessive salivation, lacrimation, urination, diarrhea,…
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