Study sets matching "pain pharmacology"

Study sets
Classes
Users

Study sets matching "pain pharmacology"

15 terms
Pain Pharmacology
Local anesthetic MOA
Bupivicane
Lidocaine
Local anesthetics given with _____
Block voltage gated sodium channels or through hydrophobic me…
Longer duration, often given for surgeries; given parentally;…
More for shorter procedures; given parentally; causes CNS exc…
Epi to increase uptake and vasoconstrict
Local anesthetic MOA
Block voltage gated sodium channels or through hydrophobic me…
Bupivicane
Longer duration, often given for surgeries; given parentally;…
Pharmacology: Pain
all of the following are opiate agonis…
an important principle in the manageme…
which class of antidepressant medicati…
The MOA of opiate analgesics can best…
hydrocodone/ibuprofen or Vicoprofen
prostaglandins are a trigger for type C fibers
selective serotonin reuptake inhibitor
binding of mu receptors to inhibit nociceptors in the CNS
all of the following are opiate agonis…
hydrocodone/ibuprofen or Vicoprofen
an important principle in the manageme…
prostaglandins are a trigger for type C fibers
38 terms
Pain Pharmacology
5 steps of pain
Nociceptive Pain
Neuropathic Pain
Pain receptors
transduction, conduction, transmission, modulation, perception
Goes through transduction, somatic is most common (easy to ID…
damage to nerve terminal, bypasses transduction, hard to treat
free nerve endings that respond to painful stimuli, found in…
5 steps of pain
transduction, conduction, transmission, modulation, perception
Nociceptive Pain
Goes through transduction, somatic is most common (easy to ID…
93 terms
Pharmacology: Pain
What is Pain?
What are the types of pain?
Chronic pain
Nociceptive pain
Subjective to the patient; whatever the patient is feeling
Acute, Chronic, Nociceptive, Neuropathic, and Cancer pain
lasting longer than 6 months
responds to pain by nerve endings
What is Pain?
Subjective to the patient; whatever the patient is feeling
What are the types of pain?
Acute, Chronic, Nociceptive, Neuropathic, and Cancer pain
151 terms
Pain Pharmacology
Nonpharm Treatments
Pharmacologic treatment groups
Steps of Analgesic ladder
Acetaminophen:... MOA
Physical therapy, CBT, Stimulation therapy (TENS units), cold…
Analgesics... Adjuvants
Bottom: non-opioid + Adjuvant... Step 2: Opioid for mild to mode…
PEROXIDE DEPENENT COX inhibition vs. COX-1 splice variant... - S…
Nonpharm Treatments
Physical therapy, CBT, Stimulation therapy (TENS units), cold…
Pharmacologic treatment groups
Analgesics... Adjuvants
28 terms
Pain Pharmacology
Acute Pain
Chronic Pain
A-Delta Fiber
C-Fiber
-Occurs in response to tissue trauma... -Accompanied by high le…
-Extends beyond healing period... -Low levels of identified pat…
-Fast, thin, myelinated fiber ... -Localized intense pain ... -Re…
-Small unmyelinated fiber ... -Long lasting pain ... -Slow, throb…
Acute Pain
-Occurs in response to tissue trauma... -Accompanied by high le…
Chronic Pain
-Extends beyond healing period... -Low levels of identified pat…
36 terms
Pain Pharmacology
morphine
codeine
pentazocine
pain
prototype strong narcotic agonist
prototype mild narcotic agonist
prototype narcotic agonist-antagonist
a multidimensional subjective experience encompassing the phy…
morphine
prototype strong narcotic agonist
codeine
prototype mild narcotic agonist
49 terms
Pharmacology-pain
Opioid identifiers
Opioid MOA
Opioid indications
Opioid contraindications
-morphone, -codone, -morph
Acts on mu, kappa, or delta receptors
Severe pain, induce anesthesia
Severe respiratory disease, GI obstructions, head injury
Opioid identifiers
-morphone, -codone, -morph
Opioid MOA
Acts on mu, kappa, or delta receptors
Pain Pharmacology
Local Anesthetics
MOA: Block Voltage Gated Na Channels
MOA: Hydrophobic Pathway
Routes of admin Local Anesthesia (phar…
Inhibit propagation or degrade sensory impulses... - first analg…
Local Anesthetics... - weak bases = ionized easily in blood, can…
Local Anesthetics... - unionized form can traverse membrane to r…
-Topical... -Infiltration (inject dilute sol subcut and let diff…
Local Anesthetics
Inhibit propagation or degrade sensory impulses... - first analg…
MOA: Block Voltage Gated Na Channels
Local Anesthetics... - weak bases = ionized easily in blood, can…
43 terms
Pharmacology Pain
Opioid
Nonopioids
Opioid Risks
Opioid Benefits
Narcotic... Acts centrally (within CNS), addiction/dependence/t…
Act peripherally, not habit forming, not controlled drugs, no…
Respiratory depression, sedation, nausea, and vomiting. Poten…
Analgesia, surpass the caught reflex, slow the motility of GI…
Opioid
Narcotic... Acts centrally (within CNS), addiction/dependence/t…
Nonopioids
Act peripherally, not habit forming, not controlled drugs, no…
35 terms
Pain Pharmacology
WHO Analgesic ladder: step 1
WHO Analgesic ladder: step 2
WHO Analgesic ladder: step 3
AS fibers vs C pain fibers
Non-opiods/adjuvants... - NSAIDs, tylenol, antidepressants, anti…
Weak opioids or strong opioid + adjuvant... - Codeine, tramadol,…
Strong opioids... - Morphine, oxy, hydro, fentanyl
Adelta: fast, sharp pain... C: slow, aching pain
WHO Analgesic ladder: step 1
Non-opiods/adjuvants... - NSAIDs, tylenol, antidepressants, anti…
WHO Analgesic ladder: step 2
Weak opioids or strong opioid + adjuvant... - Codeine, tramadol,…
43 terms
Pain Pharmacology
Nociception Pathways
1.) Transduction/Nociception
Transduction/Nociception receptors
2.) Transmission
4 stages- ability to feel pain... 1.) Transduction/Nociception... 2…
-nociceptors (specialized primary afferent neurons) convert p…
-activate based in impulse... TRPV1/2/3/TREK1 = heat (ex: capsa…
-up dorsal point of spinal cord to the brain... A-delta and C ar…
Nociception Pathways
4 stages- ability to feel pain... 1.) Transduction/Nociception... 2…
1.) Transduction/Nociception
-nociceptors (specialized primary afferent neurons) convert p…
Pain Pharmacology
opioid
Mu receptors
Kappa receptors
morphine
any drug with actions similar to morphine; natural or synthet…
most important opioid receptors - elicit analgesia along with…
2nd most important opioid receptors - only elicit analgesia,…
pure opioid agonist, strong, causes respiratory depression
opioid
any drug with actions similar to morphine; natural or synthet…
Mu receptors
most important opioid receptors - elicit analgesia along with…
33 terms
Pharmacology - Pain
"Receptors" are either _______________…
Nociception is stimulation of ________…
What are nociceptors?
What is the difference between pain an…
Neuroepithelium, sensory, transmitters (glutamate)... Neurons,…
Nociceptors
Primary afferents that respond to noxious stimuli - Adelta an…
Pain requires cortical awareness (thalamus/cortex)
"Receptors" are either _______________…
Neuroepithelium, sensory, transmitters (glutamate)... Neurons,…
Nociception is stimulation of ________…
Nociceptors
42 terms
Pain - Pharmacology
Which medication class do you use for…
What do you use for mild migraines?
How is a mild migraine classified?
How is a moderate migraine classified?
Triptans (aka 5-HT1 agonists)
- NSAIDs... - Acetaminophen w/ caffiene or NSAID... - Triptans/ Erg…
Occasional headaches w/ no functional impairment
Has nausea w/ some functional impairment
Which medication class do you use for…
Triptans (aka 5-HT1 agonists)
What do you use for mild migraines?
- NSAIDs... - Acetaminophen w/ caffiene or NSAID... - Triptans/ Erg…
41 terms
Pharmacology of pain
Define pain:
Define nociception:
What are the nociceptive fibres?
Where are cell bodies of nociceptors f…
Unpleasant sensory and emotional experience associated with a…
The neural processes of encoding noxious stimuli
Aδ (thin myelin)... C (no myelin)
1) Dorsal root ganglia... 2) Trigeminal ganglia (head and neck)
Define pain:
Unpleasant sensory and emotional experience associated with a…
Define nociception:
The neural processes of encoding noxious stimuli
69 terms
Pharmacology of pain
2 effects with opioids
Describe the spinal opiate receptor lo…
Describe the supraspinal opiate recept…
Why would you administer a systemic ad…
decrease voltage gated calcium currents (decrease stimulatory…
pre and postsynaptic (dorsal horn); synergistic analgesia wit…
medulla, hypothalamus, periaqueductal grey area, amygdala, ce…
spinal and supraspinal analgesia
2 effects with opioids
decrease voltage gated calcium currents (decrease stimulatory…
Describe the spinal opiate receptor lo…
pre and postsynaptic (dorsal horn); synergistic analgesia wit…
26 terms
Pain Pharmacology
Morphine, Codeine, Oxycodone, hydromor…
Meperidine, fentanyl
Methadone, propoxyphene
Morphine
Phenanthrenes
Phenylpiperidines
Diphenylheptanes
pure agonist
Morphine, Codeine, Oxycodone, hydromor…
Phenanthrenes
Meperidine, fentanyl
Phenylpiperidines
53 terms
pharmacology for pain
Are non opioid medications addicting?
Which drug does NOT have anti inflamma…
Which non NSAID medication is safe in…
What is the MAJOR adverse effect of Ac…
Non opioid meds are non addicting
Acetaminophen (tylenol)
Acetaminophen (tylenol)
liver toxicity
Are non opioid medications addicting?
Non opioid meds are non addicting
Which drug does NOT have anti inflamma…
Acetaminophen (tylenol)
Pain Pharmacology
Local anaesthetics mode of action
NSAIDs mode of action
NSAID effects
Prostaglandins
Na channel blockers. Decrease number of channels available to…
COX inhibitors
Anti-inflammatory, anti-pyretic, analgeisc
Sensitise nociceptors to other mediators
Local anaesthetics mode of action
Na channel blockers. Decrease number of channels available to…
NSAIDs mode of action
COX inhibitors
70 terms
Pain Pharmacology
Anesthetics
Analgesics
Gate Control Theory
Adjuvant medications
Depresses CNS characterized by absence of all sensory modalit…
Relieve pain without LOC
Non-painful stimuli shuts the gate to painful stimuli, preven…
-Medications that enhance efficacy of primary medications... -Ca…
Anesthetics
Depresses CNS characterized by absence of all sensory modalit…
Analgesics
Relieve pain without LOC
33 terms
Pain pharmacology
Transduction
Transmission
Perception
Modulation
Delta (sharp) and beta (proprioception) for peripheral nocice…
Peripheral nerve to dorsal horn. Action of opioids, alpha 2 a…
Ascending input to brain. Action of opioid alpha 2 agonists,…
Feedback to spinal tract. Action of TCAs, SSRIs, SNRIs
Transduction
Delta (sharp) and beta (proprioception) for peripheral nocice…
Transmission
Peripheral nerve to dorsal horn. Action of opioids, alpha 2 a…
Pain Pharmacology
NSAIDs
Corticosteroids
Antiseptics/disinfectants
Antibiotics, penicillins
aspirin, naproxen, ibuprofen, ketorolac, diclofenac, celecoxib
Hydrocortisone (Cortef, Solu-Cortef), methylprednisolone (Sol…
alcohol, providone-iodine, chlorhexidine, hydrogen peroxide
ampicillin (Omnipen), dicloxacillin (Dycill)
NSAIDs
aspirin, naproxen, ibuprofen, ketorolac, diclofenac, celecoxib
Corticosteroids
Hydrocortisone (Cortef, Solu-Cortef), methylprednisolone (Sol…
Pain Pharmacology
transduction
dorsal horn
prostaglandins
voltage activated sodium channels
nociceptors convert a painful stimulus into a nervous impulse
the pain signal first travels to where?
receptors at pain terminals which can activate nociceptive fi…
primary mediators of signal conduction
transduction
nociceptors convert a painful stimulus into a nervous impulse
dorsal horn
the pain signal first travels to where?
16 terms
pharmacology - pain
Morphine
Hydrocodone
Lomotil (Diphenoxylate)
Fentanyl
CII opioid analgesic, derived from poppy and PCA t1/2 = 1.5-7…
CIII semi-synthetic opioid analgesic and antitussive, compoun…
CV if compounded with atropine, antidiarrheal, t1/2 = 12-14 hrs
CII synthetic opioid analgesic indicated for chronic pain, in…
Morphine
CII opioid analgesic, derived from poppy and PCA t1/2 = 1.5-7…
Hydrocodone
CIII semi-synthetic opioid analgesic and antitussive, compoun…
40 terms
PHARMACOLOGY- PAIN
Acute Pain
Chronic Pain
Somatic Pain "healthy nerve ending"
Somatic "body pain"
presence of severe discomfort or... uncomfortable sensation, las…
persistent or recurring pain that continues for more than 6 m…
Pain that occurs because of an actual injury, generally... well-…
pertaining to or characteristic of the body or... wall of the bo…
Acute Pain
presence of severe discomfort or... uncomfortable sensation, las…
Chronic Pain
persistent or recurring pain that continues for more than 6 m…
pharmacology; pain
KEY TERMS
Acute pain
Addiction
Adjuvant analgesic drugs
...
Pain that is sudden in onset, usually subsides when treated,…
A chronic, neurobiologic disease whose development is influen…
Drugs that are added for combined therapy with a primary drug…
KEY TERMS
...
Acute pain
Pain that is sudden in onset, usually subsides when treated,…
40 terms
Pharmacology pain
fifth vital sign
nociceptors
detects pain first
transduction
pain
special type of nerve cell to detect noxious stimuli
nociceptors
noxious stimulus transformed to electrical signals in nerves
fifth vital sign
pain
nociceptors
special type of nerve cell to detect noxious stimuli
39 terms
Pain Pharmacology
Classification of types of pain
Nociceptive pain
neuropathic pain
Neuropathic pain treatment
Duration (acute, chronic, or mixed), Etiology (CA related or…
ascending pain transmission via spinal cord to cortex for pro…
either peripheral or central from changes in dorsal horn neur…
NSAIDs generally not effective and opioids have limited effic…
Classification of types of pain
Duration (acute, chronic, or mixed), Etiology (CA related or…
Nociceptive pain
ascending pain transmission via spinal cord to cortex for pro…
47 terms
Pharmacology & pain
Opioids adverse effects
Opioids transdermal patches
Opioids breakthrough pain
Opioid tolerance
euphoria, CNS depression leading to respiratory depression, N…
rotate sites, remove old before applying new, gloves, put in…
between high, long standing doses of this, PRN meds used for…
everyone has a different tolerance, take so many that you bui…
Opioids adverse effects
euphoria, CNS depression leading to respiratory depression, N…
Opioids transdermal patches
rotate sites, remove old before applying new, gloves, put in…
58 terms
pain pharmacology
local anesthesetics
mechanism of action
ion trapping
hydrophobic pathway
loss of sensation in limited region of the body by BLOCKING V…
block voltage gated Na channels ... at body pH, they are ionized…
At a pH equal to the protonatedbase's pKa, the ionized and un…
move laterally through plasma membrane to reach site of action
local anesthesetics
loss of sensation in limited region of the body by BLOCKING V…
mechanism of action
block voltage gated Na channels ... at body pH, they are ionized…
Pain Pharmacology
morphine
3 receptor classes of opioid receptors
4 classifications of opiod analgesics
stong agonists examples
opioid
mu, kappa, delta
strong agonists... mild to moderate agonists... mixed agonists-an…
fetanyl... hyrdomorphone (Dilaudid)... meperidine (demerol)... morp…
morphine
opioid
3 receptor classes of opioid receptors
mu, kappa, delta
91 terms
Pain pharmacology
Angelgesic means?
Non-option drugs mean?
Opioids drugs mean?
Anesthesia means?
Pain relief
Containing no opioid
Do contain opioid
Loss of sensation or feeling
Angelgesic means?
Pain relief
Non-option drugs mean?
Containing no opioid
51 terms
Pain Pharmacology
Mechanism of Action of Local Anesthetics
Local Anesthetics in teh flood
Where do you inject an epidural block?
Where do you inject a spinal block?
Blocks voltage gated sodium channels.
Most are weak bases so in the blood they are ionized and don'…
just above the dura
into the cerebral spinal fluid via the subarachnoid space
Mechanism of Action of Local Anesthetics
Blocks voltage gated sodium channels.
Local Anesthetics in teh flood
Most are weak bases so in the blood they are ionized and don'…
155 terms
Pharmacology of Pain
Basic Strategies of Pain Control
Drugs used for Periphery intervention
Central acting drugs
Analgesic Ladder
Attenuation or blockade of pain through intervention at the p…
NSAIDs - Later... Capsaicin... Local anesthetics... Glucocorticoids (a…
Antiepileptics ... Antidepresants ... Opioids... Muscle relaxants (adj…
Step 1: Mild pain: non-opioid, with or without adjuncts and n…
Basic Strategies of Pain Control
Attenuation or blockade of pain through intervention at the p…
Drugs used for Periphery intervention
NSAIDs - Later... Capsaicin... Local anesthetics... Glucocorticoids (a…
Pharmacology of Pain
Non-opioid analgesics
Opioid analgesics
Anticoagulants
Glucocorticoids
Act primarily in peripheral tissues to inhibit the formation…
Act primarily in the spinal cord and brain to inhibit the neu…
Intensify anticoagulant effects
Promote gastric ulceration
Non-opioid analgesics
Act primarily in peripheral tissues to inhibit the formation…
Opioid analgesics
Act primarily in the spinal cord and brain to inhibit the neu…
48 terms
Pharmacology of pain
change in pain through time
nociceptive pain
inflammatory
neuropathic
sec-mins = nociceptive activation... min-days = peripheral (?)…
acute noxious mechanical, thermal, electrical stimuli
semi-acute or chronic ischaemia, infection
chronic maladaptive plasticity after traumatic injury
change in pain through time
sec-mins = nociceptive activation... min-days = peripheral (?)…
nociceptive pain
acute noxious mechanical, thermal, electrical stimuli
Pain Pharmacology
What are the four stages of nociception?
What do nociceptors do?
Where are nociceptors located?
What do I mean when I say "nociceptors…
1. Transduction... 2. Transmission... 3. Perception... 4. Modulation
Convert painful stimulus into a nerve impulse
Widely in skin, muscle, bones, and viscera
Tuned to respond to different stimuli that are strong enough…
What are the four stages of nociception?
1. Transduction... 2. Transmission... 3. Perception... 4. Modulation
What do nociceptors do?
Convert painful stimulus into a nerve impulse
5 terms
Pain Pharmacology
What procedure is generally effective…
With respect to the onset of acute rad…
Identify the two most commonly used st…
What advantages do a local anesthetic…
Epidural steroid injections are effective for relief of pain…
Epidural steroid injections are most effective when given wit…
The two most commonly used agents for epidural steroid inject…
"A mixture of local anesthetic & steroid for the epidural inj…
What procedure is generally effective…
Epidural steroid injections are effective for relief of pain…
With respect to the onset of acute rad…
Epidural steroid injections are most effective when given wit…
Pain Pharmacology
Acetaminophen blocks prostaglandins in…
NSAIDS carry anaphylaxis risk in aspir…
tinnitus in salicylates is reversible
Name other salicylates... ... All salicylat…
NSAIDS in Periphery and CNS... Block COX enzyme... decrease prost…
AEs... renal failure (prostaglandins dilate afferent artery)... w…
Aspirin cause irreversible platelet aggregation for lifetime…
sausalito (discalced)... diflunisil (dolobid)... choline magnesium…
Acetaminophen blocks prostaglandins in…
NSAIDS in Periphery and CNS... Block COX enzyme... decrease prost…
NSAIDS carry anaphylaxis risk in aspir…
AEs... renal failure (prostaglandins dilate afferent artery)... w…
58 terms
Pharmacology- Pain
A 37-year-old patient with a history o…
Which of the following drugs inhibits…
A 55-year-old man presents with compla…
Drugs such as sulfinpyrazone are impor…
Colchicine
Allopurinol
Indomethacin
Probenecid
A 37-year-old patient with a history o…
Colchicine
Which of the following drugs inhibits…
Allopurinol
28 terms
Pharmacology Pain
pain is comprised of what two elements?
what are peripheral nerve endings call…
where are nociceptors found?
what do nociceptors respond to?
local irritation and recognition
nociceptors
skin, muscle joints, bones and viscera
tissue injury
pain is comprised of what two elements?
local irritation and recognition
what are peripheral nerve endings call…
nociceptors
31 terms
Pharmacology - pain
Barriers to pain management?
What are the 2 classifications of pain?
What are the 5 principles when treatin…
What is the dose for acetaminophen?
Inadequate knowledge of HC professionals... Cultural and social…
Nociceptive - Somatic and Visceral... Neuropathic
1. treat around the clock... 2. use max dose... 3. switch to a diff…
325mg or less q 4-6 hours
Barriers to pain management?
Inadequate knowledge of HC professionals... Cultural and social…
What are the 2 classifications of pain?
Nociceptive - Somatic and Visceral... Neuropathic
61 terms
Pharmacology of pain
step 1 (WHO) - mild pain
step 2 (WHO) - moderate pain
step 3 (WHO) - severe pain
Non-opioids include...
non-opioid, with or without adjuncts and non-drug strategies
Weak opioids +/- Step 1 +/- adjunct / non-drug strategies
Potent opioids +/- Step 1 +/- adjunct / non-drug strategies
APAP ... NSAIDS: ... - Celexcoxib (Celebrex) ... - Diclofenac (Voltare…
step 1 (WHO) - mild pain
non-opioid, with or without adjuncts and non-drug strategies
step 2 (WHO) - moderate pain
Weak opioids +/- Step 1 +/- adjunct / non-drug strategies
Pharmacology of pain
What are some types of pain
Opioids that are naturally produced in…
Opioid receptors in the body
Mechanism of action of morphine
Acute pain... Tissue injury pain... Neuropathic pain... Dysfunctional…
Proopiomelacortin ... Proenkephalin... Prodynorphin
Mu (mu1 and mu2)... Delta (delta1, delta2)... Kappa (kappa1, kappa2…
Binds to opioid receptors and causes an outflux of potassium…
What are some types of pain
Acute pain... Tissue injury pain... Neuropathic pain... Dysfunctional…
Opioids that are naturally produced in…
Proopiomelacortin ... Proenkephalin... Prodynorphin
Pharmacology of pain
How is nociceptive pain treated?
How is neuropathic pain treated?
What is somatic nociceptive pain?
What is visceral nociceptive pain?
With opioids and other analgesics
With anticonvulsants, TCA, gabapentin
Easy to describe and locate
Difficult to describe and locate
How is nociceptive pain treated?
With opioids and other analgesics
How is neuropathic pain treated?
With anticonvulsants, TCA, gabapentin
30 terms
Pharmacology of pain
What are the 3 most important types of…
Name 5 receptor target for pain treatm…
Where do opioids act?
Where does pain cause activation in th…
Nociceptive - acute... Inflammatory - Semi acute or chronic... Ne…
COX 2... NOS... NMDA and non-NMDA... NK1... Opioid receptors
PAG - periaqueductal gray... NRPG - nucleus reticularis paragiga…
Spinal cord... Thalamus... Somatosensory cortex... Anterior cingulate…
What are the 3 most important types of…
Nociceptive - acute... Inflammatory - Semi acute or chronic... Ne…
Name 5 receptor target for pain treatm…
COX 2... NOS... NMDA and non-NMDA... NK1... Opioid receptors
Pain pharmacology
NSAIDs
Aspirin
Ibuprofen/naproxen
Paracetamol
Cox inhibitorsDrugs enter hydrophobic tunnel, form... hydrogen b…
weakly COX-1 selective, irreversible acetylation,... used mainly…
weakly COX-1 selective, symptomatic... relief in rheumatoid arth…
- analgesic/antipyretic, poor anti-inflammatory,... but good ant…
NSAIDs
Cox inhibitorsDrugs enter hydrophobic tunnel, form... hydrogen b…
Aspirin
weakly COX-1 selective, irreversible acetylation,... used mainly…
25 terms
Pharmacology - Pain
Physiological Pain
Pathological Pain
Somatic Pain
Visceral Pain
Protective function... Stimulation of pain receptors or nocicep…
Generally no benefit... Central neuropathic pain... Disorders with…
Caused by injury and stimulation of pain receptors in the ski…
Results from the activation of pain receptors in the thoracic…
Physiological Pain
Protective function... Stimulation of pain receptors or nocicep…
Pathological Pain
Generally no benefit... Central neuropathic pain... Disorders with…
pharmacology of pain
morphine overdose treat with
rate to administer morphine
what lab results can increase if given…
what type of patients should you take…
narcan (naloxone)
2.5-15mg over 5 mins
amylase and lipase
ones using MAOI's within 14 days (nardil)
morphine overdose treat with
narcan (naloxone)
rate to administer morphine
2.5-15mg over 5 mins
1 of 10