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Study sets matching "pathophysiology chapter 5"

86 terms
Pathophysiology Chapter 5
Mechanical barrier; skin and mucous me…
Inflammation, Phagocytosis: a cellular…
Production of specific antibodies or c…
_________ is the body's nonspecific re…
first line
second line
third
Inflammation
Mechanical barrier; skin and mucous me…
first line
Inflammation, Phagocytosis: a cellular…
second line
44 terms
Pathophysiology chapter 5
Abscess
Adhesions
Angiogenesis
Anorexia
A localized pocket of infection or purulent exudate surrounde…
...
...
Loss of appetite
Abscess
A localized pocket of infection or purulent exudate surrounde…
Adhesions
...
19 terms
pathophysiology chapter 5 terms
allergens
allergy
anaphylaxis
antigen
antigens that cause allergic reactions
A hypersensitivity disorder. An allergy to the antigen is pos…
severe allergic response to an allergen usually leading to an…
cause allergic reactions
allergens
antigens that cause allergic reactions
allergy
A hypersensitivity disorder. An allergy to the antigen is pos…
23 terms
Pathophysiology Chapter 5
1st line of defense
2nd line of defense
3rd line of defense
Physical Barriers
innate
inflammation
acquired
skin, mucosa, gastrointestinal, and respiratory tracts; cough…
1st line of defense
innate
2nd line of defense
inflammation
18 terms
Pathophysiology Chapter 5 Vocabulary
Intracellular
Interstitial
Intravascular
Net filtration
within the cell
the space between cells and outside the blood vessels
blood plasma
as plasma flows from the arterial to the venous end of the ca…
Intracellular
within the cell
Interstitial
the space between cells and outside the blood vessels
85 terms
Pathophysiology Chapter 5
All cells of the body derived from wha…
What is differentiation?
Pluripotent
All new red blood cells come from where?
The fertilized ovum
The maturation from a nonspecific cell type, to a specialized…
The cells can differentiate into many different types of adul…
The stem cells in the bone marrow
All cells of the body derived from wha…
The fertilized ovum
What is differentiation?
The maturation from a nonspecific cell type, to a specialized…
73 terms
Pathophysiology: Chapter 5
Nonspecific (Innate) Immunity
Commensal Microorganisms
Specific Immunity
Lymphocytes
Antimicrobial defense mechanisms that are always in place and…
Symbiotic bacteria.
The "specific" immune system. It is acquired after birth and…
Cells which mediate specific immunity. They fall into three c…
Nonspecific (Innate) Immunity
Antimicrobial defense mechanisms that are always in place and…
Commensal Microorganisms
Symbiotic bacteria.
50 terms
Understanding Pathophysiology Chapter 5
What is the body's first line of defen…
When do you acquire innate resistance?
What is the 2 categories of innate res…
Second Line of defense
Innate resistance
You are born with it
Physical(cilia, skin, mucus membranes) and biochemical (saliv…
INFLAMMATION: Responsible for generating/promoting a response…
What is the body's first line of defen…
Innate resistance
When do you acquire innate resistance?
You are born with it
15 terms
Pathophysiology Chapter 5
Immunodeficient
Autoimmune
Isoimmune
Hay fever
Lack of immunity
Immunity against self
Immunity against other humans
Reaction to allergen in mucous membranes of nose and upper re…
Immunodeficient
Lack of immunity
Autoimmune
Immunity against self
45 terms
Pathophysiology Chapter 5
Definition of cerebral aneurysm
Signs on a cerebral aneurysm
Treatment of cerebral aneurysm
Factors leading to stroke
Dilation and ballooning of cerebral vessel. Usually occurs at…
Headache/nausea, nuchal rigidity, stick back and legs
Operation. If can't operate, medication to lower blood pressu…
Obesity, diabetes, smoking, hypertension, oral contraceptives.
Definition of cerebral aneurysm
Dilation and ballooning of cerebral vessel. Usually occurs at…
Signs on a cerebral aneurysm
Headache/nausea, nuchal rigidity, stick back and legs
71 terms
Braun Pathophysiology chapter 5
Resident flora
Pathogen
pathogenicity
virulence
microorganisms that live on or within the body without causin…
disease producing microbe
qualities that promote the production of disease
potency of the pathogen indicated by the ratio of the number…
Resident flora
microorganisms that live on or within the body without causin…
Pathogen
disease producing microbe
19 terms
Pathophysiology: Chapter 5 Vocab
Allergen
Allergy
Anaphylaxis
Antigen
the environmental substance that causes a reaction
the state when the immune response is too intense or hypersen…
an immediate allergic reaction characterized by contraction o…
cell marker that induces a state of sensitivity after coming…
Allergen
the environmental substance that causes a reaction
Allergy
the state when the immune response is too intense or hypersen…
19 terms
Pathophysiology - Chapter 5
First line of defense
Second line of defense
Phagocytosis
Inflammation
- is nonspecific... - mechanical or chemical barrier... - includes…
- nonspecific... - involves process of phagocytosis... - includes i…
Process by which necrophiliacs and phagocytes randomly engulf…
Sequence of events intended to limit effects of injury or dan…
First line of defense
- is nonspecific... - mechanical or chemical barrier... - includes…
Second line of defense
- nonspecific... - involves process of phagocytosis... - includes i…
49 terms
Module 3 (Chapter 5) Pathophysiology
Abscess
Acute Phase Reactants
Adhesions
Angiogenesis
Localized pocket of pus in solid tissue
Serum proteins that can be either anti- or pro-inflammatory
A fibrous band or structure by which parts abnormally adhere
The growth or proliferation of blood vessels
Abscess
Localized pocket of pus in solid tissue
Acute Phase Reactants
Serum proteins that can be either anti- or pro-inflammatory
40 terms
pathophysiology: chapter 5
immunodeficiency
autoimmune
isoimmune
antigens (allergens)
lack of immunity
immunity against itself, body attacks itself
immunity against other humans
they cause allergic reactions
immunodeficiency
lack of immunity
autoimmune
immunity against itself, body attacks itself
44 terms
Pathophysiology Chapter 5
Virulence
Infectivity
Antigenicity
Obligate parasites
Potency of a pathogen indicated by the ratio of the number of…
Proportion of exposures needed to cause an infection in an in…
Level to which a pathogen is viewed by the host immune system…
Require the host for metabolism and reproduction
Virulence
Potency of a pathogen indicated by the ratio of the number of…
Infectivity
Proportion of exposures needed to cause an infection in an in…
17 terms
Pathophysiology chapter 5
Alleles
Homozygous
Heterozygous
Huntingtons disease
Alternative forms of a gene
If two of the same allele is inherited
If two alleles are different
A neurodegenerative disease; autosomal dominant
Alleles
Alternative forms of a gene
Homozygous
If two of the same allele is inherited
135 terms
Pathophysiology-CHAPTER 5
Infectious Rhinitis Manifestations:
Infectious Rhinitis diagnosis:
Infectious Rhinitis treatment:
Sinusitis
sore throat, nonproductive cough, malaise, myalgia, low-grade…
history and physical examination
antipyretics, analgesics, antihistamines, decongestants, anti…
inflammation of the sinus cavities
Infectious Rhinitis Manifestations:
sore throat, nonproductive cough, malaise, myalgia, low-grade…
Infectious Rhinitis diagnosis:
history and physical examination
52 terms
Pathophysiology Chapter 5
sequence of DNA that contains the inst…
each set of three bases on the mRNA co…
the amino acids are linked together in…
DNA never leaves the nucleus
gene
codon
gene
transcription
sequence of DNA that contains the inst…
gene
each set of three bases on the mRNA co…
codon
Pathophysiology Chapter 5
Infection
Pathogen
Natural Flora
Communicable Disease
a state of tissue destruction caused by microorganisms
microorganisms that cause disease
microorganisms that live on or within the body without causin…
spread from person to person, often through infected blood an…
Infection
a state of tissue destruction caused by microorganisms
Pathogen
microorganisms that cause disease
65 terms
Chapter 5: Pathophysiology
aerobic
antigenic variability
antigenicity
ascending
requires oxygen for growth
a process of eluding the human host defenses; often result of…
the level to which a pathogen is viewed by the host immune sy…
the upward movement of an infection
aerobic
requires oxygen for growth
antigenic variability
a process of eluding the human host defenses; often result of…
48 terms
Pathophysiology- Chapter 5
Immunity
Two separate mechanisms function toget…
Innate (nonspecific) immunity
Barrier defenses
Resistance to disease
Innate (nonspecific) immunity... Acquired (specific) immunity
Consists of 2 parts:... - Barrier defenses... - inflammatory reaction
First line of defense is external body membranes (skin and mu…
Immunity
Resistance to disease
Two separate mechanisms function toget…
Innate (nonspecific) immunity... Acquired (specific) immunity
39 terms
Chapter 5 Pathophysiology
What is the most common cause of cance…
What is the 2nd most common cause of c…
Benign tumors
Malignant tumors
Lung cancer
Colon and rectal cancer
do not spread by infiltration of tissue
invade or grow at distant sites and destroy host tissue
What is the most common cause of cance…
Lung cancer
What is the 2nd most common cause of c…
Colon and rectal cancer
31 terms
Pathophysiology Chapter 5
What are the 3 lines of defense and gi…
What does "innate" immunity mean? What…
Manifestations of inflammation
What are the 3 main goals of the acute…
1st: innate (natural) immunity: skin, linings of GI, GU and r…
innate-natural or native, both with... adaptive-acquired, learned
Dolar-pain... Calor-Heat... Tumor-swelling... Rubor-redness
1) increased blood flow to the site of injury (vascular respo…
What are the 3 lines of defense and gi…
1st: innate (natural) immunity: skin, linings of GI, GU and r…
What does "innate" immunity mean? What…
innate-natural or native, both with... adaptive-acquired, learned
26 terms
Pathophysiology: Chapter 5
Innate vs. Adaptive Immunity
Physical Barriers
Mechanical Barriers
Biochemical Barriers
1. Innate or natural immunity, includes natural barriers and…
Covers body and organs, prevents damage from substances in th…
When pathogens try to enter through physical barriers, they m…
Epithelial cells can secrete several substances that protect…
Innate vs. Adaptive Immunity
1. Innate or natural immunity, includes natural barriers and…
Physical Barriers
Covers body and organs, prevents damage from substances in th…
27 terms
Pathophysiology Chapter 5
Hyperplasia
Neoplasia
Hypertrophy
Stem cell
-exaggerated responses to a growth stimulus, resulting in an…
-genetic growth of a single population of cells (benign or ma…
exaggerated responses to a growth stimulus, resulting in an i…
Non-specific type of cell... can become many different kinds of…
Hyperplasia
-exaggerated responses to a growth stimulus, resulting in an…
Neoplasia
-genetic growth of a single population of cells (benign or ma…
17 terms
Pathophysiology Test 1 Chapter 5
1. Define and differentiate: Incidence…
3. Be prepare to discuss the interacti…
2. Define: Relative risk: ... Be prepared…
4. Define/differentiate the terms ... Pol…
Definitions: Incidence rate: Number of new cases reported typ…
Most diseases are identified as multifactorial, a combination…
Relative risk: Page 165 ... (Incidence of the disease among peop…
A polygene, multiple factor, multiple gene inheritance, or qu…
1. Define and differentiate: Incidence…
Definitions: Incidence rate: Number of new cases reported typ…
3. Be prepare to discuss the interacti…
Most diseases are identified as multifactorial, a combination…
50 terms
Understanding Pathophysiology Chapter 5
What is the body's first line of defen…
When do you acquire innate resistance?
What is the 2 categories of innate res…
Second Line of defense
Innate resistance
You are born with it
Physical(cilia, skin, mucus membranes) and biochemical (saliv…
INFLAMMATION: Responsible for generating/promoting a response…
What is the body's first line of defen…
Innate resistance
When do you acquire innate resistance?
You are born with it
21 terms
Chapter 5 intro pathophysiology
pathophysiology
cell membrane
cell nucleus
DNA
the study of how disease processes affect the function of the…
outer covering of the cell that protects and selectively allo…
the control center of a cell
deoxyribonucleic acid; a molecule that contains the body's ge…
pathophysiology
the study of how disease processes affect the function of the…
cell membrane
outer covering of the cell that protects and selectively allo…
125 terms
Pathophysiology Chapter 5
In Immunity you have 3 lines of defens…
1st line of defense is _____ meaning t…
1st line defense has____ and ___barriers
in 1st line of defense you are trying…
1st... 2nd... 3rd
nonspecific
physical... chemical
out of the body
In Immunity you have 3 lines of defens…
1st... 2nd... 3rd
1st line of defense is _____ meaning t…
nonspecific
71 terms
Pathophysiology Infection Chapter 5
Pathogen
Pathogenicity
Virulence (Factor that affects the ran…
Inefectivity
Disease producing microorganism... - to cause disease, pathogen…
Qualities that promote the production of disease.... - involves…
potency of the pathogen ... -based by the ratio of the number of…
proportion of exposures needed to cause infection in an indiv…
Pathogen
Disease producing microorganism... - to cause disease, pathogen…
Pathogenicity
Qualities that promote the production of disease.... - involves…
94 terms
Pathophysiology Chapter 5
What is hypertrophy?
Tissue growth can be _________________…
Give an example of physiology hypertro…
What is hyperplasia?
Enlargement of pre-existing cells, increase in cell size not…
Physiologic or pathologic
Physiologic: Increase in skeletal muscle fiber size due to ex…
Tissue growth through cell multiplication which may then have…
What is hypertrophy?
Enlargement of pre-existing cells, increase in cell size not…
Tissue growth can be _________________…
Physiologic or pathologic
21 terms
Pathophysiology Chapter 5
Mechanical Barriers
Phagocytosis and Inflammation
Nonspecific Mechanisms
Phagocytosis
Defense mechanisms used by the body to protect itself from an…
What are the nonspecific processes?
The second line of defense that includes phagocytosis and inf…
The process by which neutrophils and macrophages randomly eng…
Mechanical Barriers
Defense mechanisms used by the body to protect itself from an…
Phagocytosis and Inflammation
What are the nonspecific processes?
44 terms
Chapter 5 Pathophysiology
Vasodilation
Increase
Nonspecific
Lectin Pathway
What happens to the blood vessels during inflammation to incr…
How does vascular permeability change during the inflammatory…
What is the specificity of the inflammatory process?
Which pathway of the complement system is antibody independent?
Vasodilation
What happens to the blood vessels during inflammation to incr…
Increase
How does vascular permeability change during the inflammatory…
13 terms
Pathophysiology Chapter 5
Edema
phagocytes
vasoconstriction
fibrosis
a condition characterized by an excess of watery fluid collec…
a type of cell within the body capable of engulfing and absor…
the constriction of blood vessels, which increases blood pres…
the thickening and scarring of connective tissue, usually as…
Edema
a condition characterized by an excess of watery fluid collec…
phagocytes
a type of cell within the body capable of engulfing and absor…
40 terms
pathophysiology chapter 5
first defense... second defense... third def…
first line: barrier
second line: inflammation
plasma protein systems in inflammation…
1) innate you are born with it... 2) nonspecific inflammation... 3)…
skin: acidic ... linings of GI: acidic and pH kills bacteria
1)vasodilation... 2) increased vascular pereamability... 3) WBC adh…
1) proteins help destroy compliment abilities of antibodies a…
first defense... second defense... third def…
1) innate you are born with it... 2) nonspecific inflammation... 3)…
first line: barrier
skin: acidic ... linings of GI: acidic and pH kills bacteria
88 terms
pathophysiology chapter 5
antigen
histocompatibility antigens (HLA)
1st line of defense
anatomical barriers
a protein
proteins which are found on almost every cell in the body and…
anatomical barriers... non-specific
skin and mucosal membranes prevent harmful chemicals, foreign…
antigen
a protein
histocompatibility antigens (HLA)
proteins which are found on almost every cell in the body and…
38 terms
Pathophysiology Chapter 5
innate (natural) immmunity
inflammatory response
adaptive (acquired or specific) immunity
anti-microbial peptides
the body's first line of defense; includes natural barriers a…
the second line of defense; is activated to prevent infection…
the third line of defense; involves "memory" to induce a more…
secreted by epithelial cells; kill or inhibit the growth of c…
innate (natural) immmunity
the body's first line of defense; includes natural barriers a…
inflammatory response
the second line of defense; is activated to prevent infection…
13 terms
Pathophysiology Chapter 5
General purpose of changes in cell str…
Atrophy
Hypertrophy
Hyperplasia
When confronted with stresses that endanger its normal struct…
When confronted with a decrease in work demand s or adverse e…
An increase in cell size and with it an increase in the amoun…
Increase in the number of cells in an organ or tissue. Two ty…
General purpose of changes in cell str…
When confronted with stresses that endanger its normal struct…
Atrophy
When confronted with a decrease in work demand s or adverse e…
19 terms
Pathophysiology Chapter 5
Two Main Organs of the Immune System
Other Organs
Types of cells
Function
Thymus Gland... Bone Marrow
Lymph Nodes... Spleen... Liver ... Tonsils
PMN leukocytes (Neutrophils, Eosinophils, Basophils)... Monocyte…
Phagocytosis... Allergic response... Histamine release... Become macro…
Two Main Organs of the Immune System
Thymus Gland... Bone Marrow
Other Organs
Lymph Nodes... Spleen... Liver ... Tonsils
Chapter 5 Vocab Pathophysiology
Arteritis
Bilateral
Dilated
Edema
Also called giant cell arteritis or cranial arteritis, this i…
having or relating to two sides; affecting both sides
a state of dilatation. the condition, as of an orifice or tub…
a condition of abnormally large fluid volume in the circulato…
Arteritis
Also called giant cell arteritis or cranial arteritis, this i…
Bilateral
having or relating to two sides; affecting both sides
44 terms
pathophysiology chapter 5
GENES EXPRESSED IN ALL CELLS IN TO 2 C…
OPERATING GENES
DIFFERENTIAL GENES
IN AN ADAPTIVE CELL RESPONSE,
OPERATING GENES, DIFFERENTIAL
NECESSARY FOR NORMAL FUNCTION
DIFFERENTIAL CHARACTERISTICS OF A PARTICULAR CELL TYPE
EXPRESSION OF DIFFERENTIATION GENES IS ALTERED, WHILE OPERATI…
GENES EXPRESSED IN ALL CELLS IN TO 2 C…
OPERATING GENES, DIFFERENTIAL
OPERATING GENES
NECESSARY FOR NORMAL FUNCTION
37 terms
Chapter 5 Pathophysiology
Innate immunity
Collectins
Innate immunity
Earwax
Is gained at birth
Produced by the lungs
Connected to skin and epithelial cells
Biochemical secretions that trap & kill microorganisms
Innate immunity
Is gained at birth
Collectins
Produced by the lungs
25 terms
Pathophysiology Chapter 5
adipokines
adiponectin
adiposity
leptin
hormones and proteins secreted from adipocytes that affect bo…
plasma protein that enhances cellular sensitivity to insulin,…
fat content. the lower adiposity, the greater amount of adipo…
"good" adipokine, hormone produced by adipocytes that affects…
adipokines
hormones and proteins secreted from adipocytes that affect bo…
adiponectin
plasma protein that enhances cellular sensitivity to insulin,…
37 terms
Pathophysiology Chapter 5
B lymphocytes
T lymphocytes
specific immune response
Nonspecific immune response
humoral immunity, travels in blood, antibodies
cell mediated immunity, matured in thymus gland
Ag-Ab reaction
inflammation, phagocytosis
B lymphocytes
humoral immunity, travels in blood, antibodies
T lymphocytes
cell mediated immunity, matured in thymus gland
40 terms
chapter 5 Pathophysiology
Resident flora
Pathogen
Pathogenicity
Virulence
microorganism that live within the body on non sterile area l…
Disease causing microbe
qualities that promote the production of the disease
the potency of a pathogen indicated by the ratio of the numbe…
Resident flora
microorganism that live within the body on non sterile area l…
Pathogen
Disease causing microbe
79 terms
Pathophysiology Chapter 5
Active infection
acute bronchitis
Acute lung injury
Acute respiratory distress syndrome
Phase that occurs when the primary infection can no longer be…
An inflammation of the tracheobronchial tree or large bronchi…
A slighlty less severe form of acute respiratory distress syn…
A sudden failure of the respiratory system often occurring fr…
Active infection
Phase that occurs when the primary infection can no longer be…
acute bronchitis
An inflammation of the tracheobronchial tree or large bronchi…
65 terms
Pathophysiology Chapter 5
Primary organs of the immune system
Secondary organs of the immune system
Lymphocytes
B lymphocytes
-Bone marrow ... -Thymus gland
-Spleen... -Lymph nodes... -Tonsils = lymphoid tissue... -Liver... -Respo…
-Major cells of the immune system... -Formed in the bone marrow
-Lymphocytes that remain and mature in bone marrow... -Responsib…
Primary organs of the immune system
-Bone marrow ... -Thymus gland
Secondary organs of the immune system
-Spleen... -Lymph nodes... -Tonsils = lymphoid tissue... -Liver... -Respo…
79 terms
Pathophysiology Chapter 5 Terms
active infection
acute bronchitis
acute lung injury (ALI)
acute respiratory distress syndrome (A…
Phase of tuberculosis that occurs when the primary infection…
An inflammation of the tracheobronchial tree or large bronchi…
A slightly less severe form of acute respiratory distress syn…
A sudden failure of the respiratory system often occurring fr…
active infection
Phase of tuberculosis that occurs when the primary infection…
acute bronchitis
An inflammation of the tracheobronchial tree or large bronchi…
38 terms
Pathophysiology Chapter 5
total body water (TBW)
intracellular fluid
extra cellular fluid
pediatrics TBW
60 percent body weight
2/3 of body weight
1/3 of body weight
75-80% of body weight
total body water (TBW)
60 percent body weight
intracellular fluid
2/3 of body weight
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