Study sets matching "pharm pharmacology 4"

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Study sets matching "pharm pharmacology 4"

119 terms
Pharmacology FINAL (Basic Pharm.)
loading dose
Digoxin
toxicity
peak
When immediate drug response is desired, a large initial dose…
_________ requires a loading dose when first prescribed.
The ____________ of a drug can be identified by monitoring th…
_____ drug levels indicate the rate of absorption of the drug.
loading dose
When immediate drug response is desired, a large initial dose…
Digoxin
_________ requires a loading dose when first prescribed.
21 terms
Pharm: Chapter 20 Pharmacology
Anxiety
anxiolytic
Barbiturate
Benzodiazepine
unpleasant feeling of tension, fear, or nervousness in respon…
drugs used to depress the CNS; prevents the signs and symptom…
former mainstay drug used for treatment of anziety and for se…
Drug that acts in limbic system and the reticular activating…
Anxiety
unpleasant feeling of tension, fear, or nervousness in respon…
anxiolytic
drugs used to depress the CNS; prevents the signs and symptom…
25 terms
Pharm ATI Intro to Pharmacology
A health care professional is explaini…
A health care professional is caring f…
A health care professional is caring f…
A health care professional is preparin…
A) Cardiac dysrhythmias
A) as soon as possible.
A) Patients can achieve desired effects with the use of lower…
C) Heparin via subcutaneous injection
A health care professional is explaini…
A) Cardiac dysrhythmias
A health care professional is caring f…
A) as soon as possible.
Pharmacology Pharm 2016 A
providing teaching about use of ethiny…
client who has heart failure receiving…
when should the newborn first receive…
When patient is taking predisone which…
i will fold the sticky sides of the old patch together before…
increases cardiac output and improves perfusion
2 months
bone density scans to monitor for osteoporosis
providing teaching about use of ethiny…
i will fold the sticky sides of the old patch together before…
client who has heart failure receiving…
increases cardiac output and improves perfusion
Pharmacology - GI Pharm
Which two medication classes control t…
Which two medications' MOA is to bind…
What are the drawbacks of these drugs?
What are the indications for using PPIs?
PPIs... H2 histamine receptor antagonists
Omeprazole... Lansoprazole... irreversible binding
slow onset... bioavailability decreases with food... rapid first-pa…
most widely used drug for PUD... severe GERD... nonulcer dyspepsia…
Which two medication classes control t…
PPIs... H2 histamine receptor antagonists
Which two medications' MOA is to bind…
Omeprazole... Lansoprazole... irreversible binding
36 terms
Pharm Final - cardiovascular pharmacology
You have given a drug to a NORMOTENSIV…
You have given a drug to a HYPERTENSIV…
You have given a drug to a HYPERTENSIV…
You have given a drug to a HYPERTENSIV…
c. A muscarinic receptor antagonist.
d. A diuretic.
b. An α1-adrenoceptor antagonist.
a. A β1-adrenoceptor antagonist.
You have given a drug to a NORMOTENSIV…
c. A muscarinic receptor antagonist.
You have given a drug to a HYPERTENSIV…
d. A diuretic.
90 terms
Pharm- Principles of Pharmacology
What are the three physicochemical pro…
What is the molecular size of a drug d…
What is the Partition Coefficient? (P.…
What is the equation for Partition Coe…
Molecular size, degree of water and fat solubility, charge (i…
Determined by the number and type of atoms present in the dru…
a measure of overall polarity
Concentration of drug in fat or lipid/... Concentration of drug…
What are the three physicochemical pro…
Molecular size, degree of water and fat solubility, charge (i…
What is the molecular size of a drug d…
Determined by the number and type of atoms present in the dru…
36 terms
PHARM - PHARMACOLOGY OF GONADAL HORMONES AND INHIBITORS
Ovarian Cycle
Synthetic Estrogens and Progesterones
Etonogestral
Estradiol
is the active metabolite of desogestrel- also used in *nuvari…
most commonly measured E for nonpregnant women... Estrone-estro…
Ovarian Cycle
Synthetic Estrogens and Progesterones
36 terms
Pharm 5- Geriatric Pharmacology
describe prescribing cascade
medical problem being treated with cor…
medical problem that requires drug the…
patient taking a drug fo rno medically…
avoid prescribing until dx... start with low dose, titrate slowl…
inadequate monitoring
inapprop drug selection
inapprop tx
describe prescribing cascade
avoid prescribing until dx... start with low dose, titrate slowl…
medical problem being treated with cor…
inadequate monitoring
PHARM Pharmacology of Psychotropic Medications
Elderly
40
women
Neurochemical
Who has the highest risk of suicide?
What is the mean onset of depression?
Who is depression more prevalent in?
Depression is ____________
Elderly
Who has the highest risk of suicide?
40
What is the mean onset of depression?
Pharm 5221 Pharmacology
Pharmacology
Drug Substance
Drug Product
Pharmacokinetics
The study of the effects of chemical substances on living sys…
Substances that bring about a change in a biological function…
The finished dosage form (e.g., capsule or ointment) that con…
How the body handles a drug (ADME; Absorption, Distribution,…
Pharmacology
The study of the effects of chemical substances on living sys…
Drug Substance
Substances that bring about a change in a biological function…
32 terms
Pharm - 6- Pharmacology of Pain
Primary afferent nerves
primary afferent transmitters
primary afferent fiber types
peripheral sensitization - overall eff…
- cell body in dorsal root ganglion... - projection to dorsal horn
- glutamate... - substance P... - CGRP... (pain carrying transmitters)
A-B (large, myelinated)... A-d (small, myelinated)... C (small, non…
↑ generator potentials... ↑ action potentials
Primary afferent nerves
- cell body in dorsal root ganglion... - projection to dorsal horn
primary afferent transmitters
- glutamate... - substance P... - CGRP... (pain carrying transmitters)
22 terms
Pharm: Ocular Pharmacology Fitz
Closed angle glaucoma
Open angle glaucoma
Route of absorption of anti-glaucoma m…
Cholinergic Agonists MOA (Pilocarpine)
iris abnormally positioned to block aqueous outflow through a…
aqueous outflow pathway diminished, most common, usually due…
Topical as 1st line... -pass rapidly through nasolacrimal duct i…
Pilocarpine, incr trabecular aqueous outflow by contracting c…
Closed angle glaucoma
iris abnormally positioned to block aqueous outflow through a…
Open angle glaucoma
aqueous outflow pathway diminished, most common, usually due…
89 terms
Pharm Week 1: Principles of Pharmacology
right drug, right patient, right dose,…
right assessment, right documentation,…
effectiveness, safety, and selectivity
effectiveness
What are the five medication rights?
What are the additional rights added to the original five med…
What are the three properties of an ideal drug?
This property of an ideal drug describes how a drug should el…
right drug, right patient, right dose,…
What are the five medication rights?
right assessment, right documentation,…
What are the additional rights added to the original five med…
41 terms
Pharmacology - basic princ of pharm
toxicology
pharmacotherapeutics
pharmacodynamics
pharmacokinetics
the study of the harmful effects of chemicals
use of specific drugs to prevent, treat or diagnose disease
- analysis of drug impact on the body: mechanism of action... -…
how the drug is handled in the body... three divisions: absorpti…
toxicology
the study of the harmful effects of chemicals
pharmacotherapeutics
use of specific drugs to prevent, treat or diagnose disease
18 terms
Pharmacology- cardiovascular pharm- antihyperlipidemics (cholesterol)
Hyperlipidemia ... Ideal values
Hypertriglyceridemia
Total cholesterol (Tc) =
Low density lipoprotein is dependent o…
Causes about half of all deaths in the united states, correla…
Refers to elevation of triglycerides, such as acute pancreati…
Hdl+ ldl+ vldl (tg/5) ... So Tc-hdl-vldl=ldl (lol tells you if…
Risk factors such as sex, age, smoking history, high blood pr…
Hyperlipidemia ... Ideal values
Causes about half of all deaths in the united states, correla…
Hypertriglyceridemia
Refers to elevation of triglycerides, such as acute pancreati…
169 terms
Pharm: Core Concepts in Pharmacology
drug classification
prototype drugs
generic name
trade name
groups drugs by the way they work or what they do
a well-understood, model drug that is representative of simil…
- assigned by the US Adopted Name Council (USANC)... - drug name…
- assigned by the company marketing the drug... - a brand or pro…
drug classification
groups drugs by the way they work or what they do
prototype drugs
a well-understood, model drug that is representative of simil…
38 terms
Pharm 8 Introduction to Autonomic Pharmacology
What part of the ANS is known as the t…
What part of the ANS is known as the c…
The innervation of what organ does not…
Is the parasympathetic or sympathetic…
sympathetic
parasympathetic
adrenal medulla
sympathetic system
What part of the ANS is known as the t…
sympathetic
What part of the ANS is known as the c…
parasympathetic
14 terms
Pharmacology- endocrine pharm- antithyroid drugs
Thyroid gland ... Together the hormones…
Thyroid hormones are critical for
The ratio between the two hormones is…
Thyroid metabolism affects
Gland of anatomical prominence that secretes the thyroid horm…
Nervous, skeletal, and reproductive tissues
4:1 (T4:T3), but T3 is is three to four times more potent tha…
the metabolism of drugs, food products, secretion of hormones
Thyroid gland ... Together the hormones…
Gland of anatomical prominence that secretes the thyroid horm…
Thyroid hormones are critical for
Nervous, skeletal, and reproductive tissues
Pharm: CNS Pharmacology
______ was a drug use for hypertension…
____ inhibits the storage of amine NTs…
_____ is due to decreased amine-depend…
The prototypical agent of tricyclic an…
Reserpine
Reserpine
Depression
Amitriptyline
______ was a drug use for hypertension…
Reserpine
____ inhibits the storage of amine NTs…
Reserpine
Pharmacology: orientation to pharm
therapeutic response
non-therapeutic response
onset
peak
target response
adverse effects (side effects)
time until initial effect
highest concentration
therapeutic response
target response
non-therapeutic response
adverse effects (side effects)
133 terms
PHARM: Pharmacology Test 1
define drug
define pharmacology
define therapeutics
how does the ideal medication exist?
Any chemical that can affect living processes. ... By this defi…
The study of drugs and their interactions with living systems…
aka pharmacotherapeutics. The medical use of drugs.
In theory only: there is no such thing as a perfect drug.
define drug
Any chemical that can affect living processes. ... By this defi…
define pharmacology
The study of drugs and their interactions with living systems…
21 terms
Pharm, Introduction to Pharmacology
Schedule 1 Drugs
Schedule 2 drugs
Schedule 3 drugs
Schedule 4 drugs
highest abuse potential ... highest physical and psychological d…
High abuse potential ... high physical and psychological depende…
moderate abuse potential and physical dependence... high psychol…
lower abuse potential... lower physical and psychological depend…
Schedule 1 Drugs
highest abuse potential ... highest physical and psychological d…
Schedule 2 drugs
High abuse potential ... high physical and psychological depende…
Pharmacology Pharm sem
Target protein mediated
Structural proteins
Tubulins... Microtubules
Vincristine and Paclitaxel -antineopla…
Alter the physiology
Form cell framework and cytoskeleton
Important during mitosis under structural protein, it has axo…
Example drugs of structural protein (3)
Target protein mediated
Alter the physiology
Structural proteins
Form cell framework and cytoskeleton
Pharm Lecture 76- Receptor Pharmacology
Drug-Receptor Complex (DR)
Types of Receptors
voltage gated channel
Ligand gated channel
- Macromolecule by which the ligand interacts to induce a cel…
1)an agonist will bind which will open a channel (eg.sodium,…
*the channel is opened by a difference in voltage... *ex/ sodiu…
*something has to bind ... *ex/a barbiturate will bind to the G…
Drug-Receptor Complex (DR)
- Macromolecule by which the ligand interacts to induce a cel…
Types of Receptors
1)an agonist will bind which will open a channel (eg.sodium,…
46 terms
Pharm Exam 1-Pharmacology for Nursing
Pharmacology comes from the greek work…
Pharmacology definition
Drug definition
Pharmacodynamics
Poision or potion/the study of poison
The study of the manner in which the function of living syste…
Any chemical substance other than those required for normal s…
How drugs interact with cells, tissues, and organs
Pharmacology comes from the greek work…
Poision or potion/the study of poison
Pharmacology definition
The study of the manner in which the function of living syste…
22 terms
Pharm Final: Intro to Pharmacology (FINAL)
What are the rights of medication admi…
Oral administration advantages/disadva…
GI tubes advantages/disadvantages
Sub Q injection advantages/disadvantages
right drug, right dose, right patient, right route, right tim…
Simple - can be used by most people. Convenient and inexpensi…
For patients who cannot take oral, can be used for long perio…
Generally painless, small needles can be used, insulin and he…
What are the rights of medication admi…
right drug, right dose, right patient, right route, right tim…
Oral administration advantages/disadva…
Simple - can be used by most people. Convenient and inexpensi…
23 terms
Pharm TECH (pharmacology)(Digestive)
antacids
H2 antagonists
proton pump inhibitors
coating agent
neutralize stomach acid to prevent reflux
blocks gastric acid
helps with acid reflux
forms coat over ulcer against gastric acid, pepsin and bile s…
antacids
neutralize stomach acid to prevent reflux
H2 antagonists
blocks gastric acid
Pharm- CNS Pharmacology
sedative/hypnotic, anxiolytics, hypnot…
insomnia, anxiety, seizures, alcohol w…
antidepressant
xerostomia and bruxism
What are the three types of antianxiety agents?
What are antianxiety agents used for?
What drugs inhibit reuptake of norepinephrine/serotonin and i…
What are adverse effects of antidepressants agents related to…
sedative/hypnotic, anxiolytics, hypnot…
What are the three types of antianxiety agents?
insomnia, anxiety, seizures, alcohol w…
What are antianxiety agents used for?
108 terms
Pharm - Cardiovascular Pharmacology
Largest area of Pharmacology?
Control of BP
Classes of BP Medications
What do Diuretics do?
Cardiovascular meds
System BP ... MAP = (HR x SV) x TPR ... Therefore, any medication…
- diuretics ... - ACE inhibitors and ARBs... - vasodilators ... - alph…
Act on kidneys... - increase excretion of sodium and water ... - de…
Largest area of Pharmacology?
Cardiovascular meds
Control of BP
System BP ... MAP = (HR x SV) x TPR ... Therefore, any medication…
128 terms
Pharm- endocrine pharmacology
Endocrine Glands
Hypothalamus
Pituatry
Anterior lobe
...
-responsible for the control and release of hormones that are…
-gland is responsible for making a number of hormones that ar…
-GH... -LH... -FASH... -TSH... -ACTH... -Pr
Endocrine Glands
...
Hypothalamus
-responsible for the control and release of hormones that are…
16 terms
Pharm- Pharmacology Principles
Pharmacokinetics
Pharmacokinetics
Absorption
Distribution
Study of drug movement throughout the body
Composed of 4 processes: absorption, distribution, metabolism…
movement of a drug from its site of administration into the b…
drug movement from the blood to the interstitial space of tis…
Pharmacokinetics
Study of drug movement throughout the body
Pharmacokinetics
Composed of 4 processes: absorption, distribution, metabolism…
26 terms
Pharmacology: Intro to Pharm
Pharmacology:
Toxicology:
Pharmacy:
Prescription medication:
"Pharmacology is the biomedical science concerned with the in…
"Toxicology is the science of poisons and toxicity. It focuse…
"the science and profession concerned with the preparation, s…
drugs whose sale is restricted and available only with a pres…
Pharmacology:
"Pharmacology is the biomedical science concerned with the in…
Toxicology:
"Toxicology is the science of poisons and toxicity. It focuse…
160 terms
Pharm - Autonomic Pharmacology
why can't you just administer straight…
physiologic functions of Ach
what is bethanechol (urecholine) used…
how does bethanechol (urecholine) work?
it cannot penetrate membranes and it is rapidly inactivated b…
decreases heart rate, cardiac output, blood pressure; increas…
urinary atony (postpartum and post operative non-obstructive…
stimulates detrusor muscle while trigone and sphincter are re…
why can't you just administer straight…
it cannot penetrate membranes and it is rapidly inactivated b…
physiologic functions of Ach
decreases heart rate, cardiac output, blood pressure; increas…
116 terms
Pharm 38 Pharmacology of Cancer
antimetabolites
adenine and guanine
cytosine, thymine and uracil
nucleosides
inhibit the synthesis of nucleotides and thus DNA and RNA
purines
pyrimidines
purines/pyrimidines conjugated to ribose/deoxyribose
antimetabolites
inhibit the synthesis of nucleotides and thus DNA and RNA
adenine and guanine
purines
79 terms
Pharmacology: General Pharm
Indications
Contraindications
Pharmacokinetics
Pharmacodynamics
reasons for using a drug
reasons for not using a drug
the way drugs move into, through, and out of the body
the mechanisms of action of a drug and its biological & physi…
Indications
reasons for using a drug
Contraindications
reasons for not using a drug
18 terms
Pharmacology: Autonomic Pharm
Cholinomimetic Esters: acetylcholine
Cholinomimetic Esters: Methacholine
Cholinomimetic Esters: Carbachol
Cholinomimetic Esters: Bethanechol
Cataract surgery (produces complete miosis). Muscarinic and N…
Asthma Diagnosis Muscarinic. Very similar to ACh. Longer dura…
Glaucoma (lower intraocular pressure); eye surgery *Muscarini…
Relief of urinary retention; GER-gastroesphageal refulx Musca…
Cholinomimetic Esters: acetylcholine
Cataract surgery (produces complete miosis). Muscarinic and N…
Cholinomimetic Esters: Methacholine
Asthma Diagnosis Muscarinic. Very similar to ACh. Longer dura…
86 terms
Pharm 7- Pharmacology of the Eye
Describe the 1st Order (Central) Sympa…
Describe the 2nd Order (Preganglionic)…
Describe the 3rd Order (Postganglionic…
What receptor is this Iris Dilator mus…
Cell body is in Hypothalamus, Axons descent to brain stem and…
Axons exit spinal column, ascend the sympathetic chain and th…
Axons ride along the Common Carotid A. The Internal Carotid A…
Adrenergic, mainly alpha 1 few beta
Describe the 1st Order (Central) Sympa…
Cell body is in Hypothalamus, Axons descent to brain stem and…
Describe the 2nd Order (Preganglionic)…
Axons exit spinal column, ascend the sympathetic chain and th…
36 terms
Pharm 8 Introduction to Autonomic Pharmacology
What part of the ANS is known as the t…
What part of the ANS is known as the c…
The innervation of what organ does not…
Is the parasympathetic or sympathetic…
sympathetic
parasympathetic
adrenal medulla
sympathetic system
What part of the ANS is known as the t…
sympathetic
What part of the ANS is known as the c…
parasympathetic
Pharm - Ocular Pharmacology
Brimonidine
Timolol/ Carteolol
Betoxolol
Epinephrine
Decreases production. A2 autoreceptor agonist. Stimulated Gi…
B1/ B2 antagonists. Block activation of Gs and decreases cAMP
B1 antagonist. Less effective but will not cause breathing pr…
A1 and A2 agonist. Useful for open angle glaucoma due to vaso…
Brimonidine
Decreases production. A2 autoreceptor agonist. Stimulated Gi…
Timolol/ Carteolol
B1/ B2 antagonists. Block activation of Gs and decreases cAMP
pharm 2 pharmacology
VTE
DVT
pain location associated with VTE
risk factors for VTE
venous thrombo embolism
deep vein thrombosis
not always in the same place as the clot
over 75 yrs. cancer. hx of VTE. obesity. immobility. (prego,…
VTE
venous thrombo embolism
DVT
deep vein thrombosis
92 terms
Pharm 512 - Pharmacology of Hypertension
3 classes of Diuretics
3 Thiazide diuretics drugs
3 Loop diuretics
2 Potassium diuretics
Thiazide diuretics ... Loop diuretics ... Potassium- sparing diuret…
Chlorthalidone ... Hydrochlorothiazide... Indapamide
Bumetanide ... Furosemide ... Torsemide
Amiloride ... Triamterene
3 classes of Diuretics
Thiazide diuretics ... Loop diuretics ... Potassium- sparing diuret…
3 Thiazide diuretics drugs
Chlorthalidone ... Hydrochlorothiazide... Indapamide
20 terms
Pharmacology Ch. 1Orientation to Pharm.
drug
pharmacology
clinical pharmacology
therapeutics (aka pharmacotherapeutics)
any chemical that can affect living processes
study of drugs and their interactions with living systems; dr…
study of drugs in humans
the use of drugs to diagnose, prevent, or treat disease or to…
drug
any chemical that can affect living processes
pharmacology
study of drugs and their interactions with living systems; dr…
Pharm: Intro to CNS Pharmacology
All _______ possess sedative-hypnotic…
______ are sedative-hypnotic drugs but…
_____ is a barbiturate used for anesth…
______ is a barbiturate used for treat…
Benzodiazepines
Barbiturates
Thiopental
Phenobarbital
All _______ possess sedative-hypnotic…
Benzodiazepines
______ are sedative-hypnotic drugs but…
Barbiturates
62 terms
Exam 1 Pharm - Pharmacology/Pharmacodynamics
What are pharmacodynamics?
Drugs can only do...
What is a response relationship as it…
What is maximal efficacy?
study of what drugs do to the body, how medicine changes the…
What the body knows, it can enhance something or stop somethi…
the relationship between the size of a dose and the intensity…
largest effect that a drug can produce
What are pharmacodynamics?
study of what drugs do to the body, how medicine changes the…
Drugs can only do...
What the body knows, it can enhance something or stop somethi…
23 terms
Pharmacology 3 pharm class
Escitalopram oxalate (Lexapro)
lorazepram (Ativan)
zolpidem (Ambien)
phenobarbital (Luminal)
selective serotonin uptake inhibitor
benzoodiazepine, GABA receptor agonist
nonbenzodiazepine GABA receptor agonist, non barbituate CNS d…
barbituate, GABA receptor aonist
Escitalopram oxalate (Lexapro)
selective serotonin uptake inhibitor
lorazepram (Ativan)
benzoodiazepine, GABA receptor agonist
Pharm: Antenatal and Perinatal Pharmacology
HELLP
Pregnancy Category A Drugs
Pregnancy Category B Drugs
Pregnancy Category C Drugs
Hemolysis, Elevated Liver Enzymes, Low Platelet count... -More s…
-well-controlled human studies... -No demonstrable risk in *Trim…
-Well controlled animal studies... -No demonstrable risk evident
-Well controlled animal studies: risk evident... -No human studi…
HELLP
Hemolysis, Elevated Liver Enzymes, Low Platelet count... -More s…
Pregnancy Category A Drugs
-well-controlled human studies... -No demonstrable risk in *Trim…
160 terms
Pharm - Autonomic Pharmacology
why can't you just administer straight…
physiologic functions of Ach
what is bethanechol (urecholine) used…
how does bethanechol (urecholine) work?
it cannot penetrate membranes and it is rapidly inactivated b…
decreases heart rate, cardiac output, blood pressure; increas…
urinary atony (postpartum and post operative non-obstructive…
stimulates detrusor muscle while trigone and sphincter are re…
why can't you just administer straight…
it cannot penetrate membranes and it is rapidly inactivated b…
physiologic functions of Ach
decreases heart rate, cardiac output, blood pressure; increas…
160 terms
Pharm - Autonomic Pharmacology
why can't you just administer straight…
physiologic functions of Ach
what is bethanechol (urecholine) used…
how does bethanechol (urecholine) work?
it cannot penetrate membranes and it is rapidly inactivated b…
decreases heart rate, cardiac output, blood pressure; increas…
urinary atony (postpartum and post operative non-obstructive…
stimulates detrusor muscle while trigone and sphincter are re…
why can't you just administer straight…
it cannot penetrate membranes and it is rapidly inactivated b…
physiologic functions of Ach
decreases heart rate, cardiac output, blood pressure; increas…
52 terms
Pharm - Pulmonary Pharmacology
Reasons for Pulmonary Medications
Types of Meds for Respiratory Tract Ir…
What are Antitussives?
Types of Antitussives
1. Control of respiratory tract irritation and secretion... 2. B…
- antitussives... - decongestants ... -mucolytics/expectorants... - an…
Cough suppressants
- codeine (other opioids) ... - antihistamines ... - others
Reasons for Pulmonary Medications
1. Control of respiratory tract irritation and secretion... 2. B…
Types of Meds for Respiratory Tract Ir…
- antitussives... - decongestants ... -mucolytics/expectorants... - an…
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