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Study sets matching "pharm"

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Study sets matching "pharm"

68 terms
Pharmacology
Calculate Vd
Calculate clearance (CL)
Calculate T1/2 in first order eliminat…
Calculate Loading Dose
Amount of drug in body/[in plasma]
= rate of elimination/[in plasma] ... =Vd*Elimination Constant
=0.693*Vd/CL
=[target at SS]*Vd/F... F=Bioavaliability
Calculate Vd
Amount of drug in body/[in plasma]
Calculate clearance (CL)
= rate of elimination/[in plasma] ... =Vd*Elimination Constant
709 terms
Pharmacology
Multi-dose bottles
OTC meds
Drug absorption
first-pass effect... revise this!
Discard & get new bottle if soiled
Be aware that OTC meds may contain the same active medication…
Drug absorption is influenced by liver (hepatic) function. (1…
Hepatic degradation or alteration of a drug taken by mouth, a…
Multi-dose bottles
Discard & get new bottle if soiled
OTC meds
Be aware that OTC meds may contain the same active medication…
99 terms
Pharmacology
STUDY CONSIDERATIONS
Pharmaceutic Phases
Pharmacokinetics
4 Characteristics of Pharmacokinetics
INDICATIONS - why giving certain products?... INTERACTIONS... MONIT…
movement of drugs within the body
1. Absorption... 2. Distribution... 3. Metabolism (AKA biotransform…
STUDY CONSIDERATIONS
INDICATIONS - why giving certain products?... INTERACTIONS... MONIT…
Pharmaceutic Phases
235 terms
Pharmacology
Pharmacology
therapeutic effects
side or adverse effects
Name the different body systems that d…
the study of drugs and their effect on the human body
positive effects drugs have on the body; intended effects
negative effects drugs have on the body; unintended effects
- Neurological... - Musculoskeletal... - Respiratory... - Cardiovascul…
Pharmacology
the study of drugs and their effect on the human body
therapeutic effects
positive effects drugs have on the body; intended effects
51 terms
Pharmacology
Analgesic
Anesthetic
Antacid
Antianxiety
An agent that relieves pain without causing loss of conscious…
An agent that produces a lack of feeling. May be local or gen…
An agent that neutralizes acid.
An agent that relieves anxiety and muscle tension.
Analgesic
An agent that relieves pain without causing loss of conscious…
Anesthetic
An agent that produces a lack of feeling. May be local or gen…
122 terms
Pharmacology
definition of a drug, examples
pharmacodynamics vs pharmacokinetics
agonist & biased agonism (aka agonist…
antagonist vs indirect antagonist
broad definition: chemical substance alters physical/mental w…
pharmacodynamics- action of a drug on the body; therapeutic/t…
binds to receptor and produces biological response... biased ag…
direct antagonist- binds to receptor but doesn't produce biol…
definition of a drug, examples
broad definition: chemical substance alters physical/mental w…
pharmacodynamics vs pharmacokinetics
pharmacodynamics- action of a drug on the body; therapeutic/t…
506 terms
Pharmacology
Selective Cox-2 inhibitors
Neuroleptic malignant Syndrome
Modafinil
Tetracyclines
eg. celecoxib. ... Cox-2 is an inducible enzyme that is unregul…
adverse reaction to antipsychotic medication characterized by…
first line treatment for narcolepsy. ... Amphetamines are secon…
are teratogenic and can cause fetal bone growth retardation a…
Selective Cox-2 inhibitors
eg. celecoxib. ... Cox-2 is an inducible enzyme that is unregul…
Neuroleptic malignant Syndrome
adverse reaction to antipsychotic medication characterized by…
59 terms
Pharmacology
Propranolol
Strongest bond
weakest bond
Law of Mass Action
beta-adrenergic antagonist... blocks the action of epinephrine a…
ionic
van der waals
Rate of Association=K1[C][R]... Rate of Dissociation=k-1[CR]
Propranolol
beta-adrenergic antagonist... blocks the action of epinephrine a…
Strongest bond
ionic
371 terms
Pharmacology
What are the 3 main categories of anta…
What is the mode of action of competit…
What is the mode of action of a pathwa…
What is the mode of action of a functi…
- Competitive... - Non-competitive, at the receptor (allosteric…
Block binding of agonist, by "clogging" the binding sites of…
Prevent agonist action, by blocking the entire pathway
Prevent agonist action, by blocking specific parts of the pat…
What are the 3 main categories of anta…
- Competitive... - Non-competitive, at the receptor (allosteric…
What is the mode of action of competit…
Block binding of agonist, by "clogging" the binding sites of…
207 terms
Pharmacology
3 areas of pharmacology
define pharmacology
define drug
what areas make up pharmacology?
General: for example muscle relaxants, local anesthetics... Syst…
the study of how drugs affect the body; deals with actions of…
a substance/chemical that changes/alters biological function
1. Drug: physical and chemical properties, preparation and di…
3 areas of pharmacology
General: for example muscle relaxants, local anesthetics... Syst…
define pharmacology
the study of how drugs affect the body; deals with actions of…
80 terms
Pharmacology
Antihistamine
Anti-inflammatory; Corticosteriod
Anti-inflammatory; Corticosteriod
Anti-inflammatory; Corticosteriod
Chlorpheniramine Maleate
Deltasone; Prednisone
Dexamethasone Sodium Phosphate
Dexamathasone Solution
Antihistamine
Chlorpheniramine Maleate
Anti-inflammatory; Corticosteriod
Deltasone; Prednisone
77 terms
Pharmacology
Phase II metabolism
Pharmacokinetics
Pharmacodynamics
Metabolism
Usually aid in elimination of the drug
'What the body does to the drug' ADME
'What the drug does to the body'
Usually reduces amount of active drug
Phase II metabolism
Usually aid in elimination of the drug
Pharmacokinetics
'What the body does to the drug' ADME
315 terms
Pharmacology
What is pharmacodynamics?
What is efficacy?
What is potency?
What is pharmacokinetics?
What the drug does to the body.
The capacity of a drug to produce an effect.
The amount of a drug required to produce an effect.
What the body does to the drug.
What is pharmacodynamics?
What the drug does to the body.
What is efficacy?
The capacity of a drug to produce an effect.
32 terms
Pharmacology
Five rights of medication
Affinity
Blood Brain Barrier
Pharmacognosy
medication, dose, frequency, route, patient
how strong a med with bind with the receptor site
semipermeable membrane between blood and brains very specific…
study of drugs obtained from natural plant/animal sources
Five rights of medication
medication, dose, frequency, route, patient
Affinity
how strong a med with bind with the receptor site
71 terms
pharmacology
pharmacology
pharma v. toxicology
naturally occuring v. labratory made
enantiomer/sterroisomer
origin, nature, chemistry, effect, uses of a drug including a…
toxi is all the same except for poisons. Also the methods of…
naturel occuring drugs may have impurities, and exact dosing…
altering structure of exsisting drug to elminate side effects…
pharmacology
origin, nature, chemistry, effect, uses of a drug including a…
pharma v. toxicology
toxi is all the same except for poisons. Also the methods of…
340 terms
Pharmacology
dexaroxane how to protect heart??? mec…
antipsychotics with retinal deposits,…
antipsychotics with weight gain, which…
different from physostigmine from pyri…
As a derivative of EDTA, dexrazoxane chelates iron and thus r…
thioridazine... corneal deposit: chlorpromazine... eopasidone: prol…
olanzapine: weight gain... clozapine: agranulocytosis, seizure
so-cross BBB... do-not cross BBB... so-atropine antidote... do-MG
dexaroxane how to protect heart??? mec…
As a derivative of EDTA, dexrazoxane chelates iron and thus r…
antipsychotics with retinal deposits,…
thioridazine... corneal deposit: chlorpromazine... eopasidone: prol…
65 terms
Pharmacology
Clearance of drug calculation
How long does a drug infused at a cons…
Half life calculation
Loading dose calculation
Clearance = Volume of plasma clear of drug/per unit time ... CL…
4-5 half lives... Independent of dose and dosing frequency
= 0.693 x Volume of distribution/CL
Where Cp is the desired plasma concentration and F is the fre…
Clearance of drug calculation
Clearance = Volume of plasma clear of drug/per unit time ... CL…
How long does a drug infused at a cons…
4-5 half lives... Independent of dose and dosing frequency
217 terms
Pharmacology
Pharmicological regulation is done by…
What is the definition of a drug?
What is a Schedule I drug?
What is a Schedule II drug?
Health products and food branch, Canadian food and drug act,…
used in the diagnosis,treatment,mitigation or prevention of a…
Narcotics
cannibis
Pharmicological regulation is done by…
Health products and food branch, Canadian food and drug act,…
What is the definition of a drug?
used in the diagnosis,treatment,mitigation or prevention of a…
101 terms
Pharmacology
Grandiose delusions
Apathy
Can result from treatment with haloper…
Can include involuntary, repetitive mo…
Positive symptoms of schizophrenia include
Negative symptoms of schizophrenia include
Extrapyramidal symptoms
Side-effects of haloperidol treatment
Grandiose delusions
Positive symptoms of schizophrenia include
Apathy
Negative symptoms of schizophrenia include
Pharmacology
Clindamycin
Penecillin
Zole
True
What is the #1 Backup Antibiotic prescribed for Premedication
The most likely antibiotic to produce a rash
Many of the anti-fungal drugs used in dentistry have what end…
(t/f) Retrovir is a common HIV medication.
Clindamycin
What is the #1 Backup Antibiotic prescribed for Premedication
Penecillin
The most likely antibiotic to produce a rash
35 terms
Pharmacology
Acetaminophen Classifications
Labs to monitor when using Acetaminophen
acetaminophen side effects
Acetaminophen uses/cautions/action
Pharmacotherapeutic: central analgesic ... Clinical: non-narcoti…
Increase serum ALT, AST, bilirubin, prothrombin
Hypersensitivity reaction
Uses: Relief for mild to moderate pain, fever, iv: management…
Acetaminophen Classifications
Pharmacotherapeutic: central analgesic ... Clinical: non-narcoti…
Labs to monitor when using Acetaminophen
Increase serum ALT, AST, bilirubin, prothrombin
pharmacology
heparin
weight
dextran
30
this is a drug that interferes with the blood clotting mmecha…
an mg is a measurement of
the solutions used intravenously to replace plasma when plasm…
how many milliliters are in 1 ounce?
heparin
this is a drug that interferes with the blood clotting mmecha…
weight
an mg is a measurement of
32 terms
Pharmacology
___ is the study of the site of action…
Toxicology is the study of ___ effects…
___ is the combination of 2 drugs with…
Tolerance is acquired insensitivity, w…
Pharmacodynamics ... mechanism of action ... pharmacokinetics... quant…
adverse... pharmacogenomics
Summation ... Additive ... ASA (acetylsalicylic acid; aspirin) and…
one prior exposure... tachyphylaxis... chronic drug use... tyrosine ... o…
___ is the study of the site of action…
Pharmacodynamics ... mechanism of action ... pharmacokinetics... quant…
Toxicology is the study of ___ effects…
adverse... pharmacogenomics
19 terms
Pharmacology
Pharmacology
Pharmacodynamics
Pharmacokinetics
Why is pharmacology important for nurs…
the scientific study of drugs and how they are used in medicine
what the drug does to the body... - the mechanism of action, cel…
what the body does to a drug ... - what factors determine the ma…
-administering drugs... -assessing drug effects... -intervening to…
Pharmacology
the scientific study of drugs and how they are used in medicine
Pharmacodynamics
what the drug does to the body... - the mechanism of action, cel…
275 terms
Pharmacology
Contraindications
Therapeutic index *
Tolerance *
Dependence *
Any characteristic of the patient, especially a disease state…
The ratio between a drug's therapeutic effects and its toxic…
A decreasing response to repeated drug doses.
A physiological or psychological need for a drug.
Contraindications
Any characteristic of the patient, especially a disease state…
Therapeutic index *
The ratio between a drug's therapeutic effects and its toxic…
104 terms
Pharmacology
Cholinergics
Alzheimer's
Aricept
Cholinergic effects
Stimulate parasympathetic receptors. + affinity + efficacy.
Deficiency of Acetylcholine
Inhibits Acetylcholinesterase
Lowered HR, BP (SLUDGEM)
Cholinergics
Stimulate parasympathetic receptors. + affinity + efficacy.
Alzheimer's
Deficiency of Acetylcholine
116 terms
Pharmacology
Davis model
ionotropes
metabotropes
transmembrane receptors
low concentration of aminoglycosides induce protein misreadin…
drugs that bind to ion channels and change conductance
heptahelical / 7-transmembrane receptors coupled to G-proteins
extracellular domains = change within cell by activating / in…
Davis model
low concentration of aminoglycosides induce protein misreadin…
ionotropes
drugs that bind to ion channels and change conductance
322 terms
Pharmacology
Neonatal animals are less tolerant of…
Decreased function of what organ would…
Generic name for a drug is also called:
You're asked to dminister a drug that…
Biotransformed (metabolized) more slowly
Liver
Nonproprietary name
Order or purchase 25 mg tabs for dosing schedule
Neonatal animals are less tolerant of…
Biotransformed (metabolized) more slowly
Decreased function of what organ would…
Liver
126 terms
Pharmacology
GENERAL STUFF
First pass
Pharmacodynamics
General stuff
High first pass (less of the drug reaching the destination)... L…
What the drug actually does at the site of action
GENERAL STUFF
General stuff
First pass
High first pass (less of the drug reaching the destination)... L…
55 terms
Pharmacology
What are symptoms of Salicylism?
What are symptoms of aspirin toxicity?
What classifications does Aspirin fall…
What are some examples of NSAIDs?
tinnitus, diaphoresis, headache, dizziness and respiratory al…
mild symptoms of Salicylism plus high fever, acidosis, dehydr…
NSAID and antiplatelet aggregator
naproxen, ASA, ibuprofen, meloxicam, celecoxib
What are symptoms of Salicylism?
tinnitus, diaphoresis, headache, dizziness and respiratory al…
What are symptoms of aspirin toxicity?
mild symptoms of Salicylism plus high fever, acidosis, dehydr…
119 terms
Pharmacology
Medications for Parkinson's Disease
Hallmark ADR of Levodopa/Carbidopa
Example of an Anticholinergic
Hallmark ADRs of Benadrly
Levodopa/Carbidopa
staining of sheets/clothing
Benadryl
sedation/insomnia, tachycardia, dry mouth, constipation, blur…
Medications for Parkinson's Disease
Levodopa/Carbidopa
Hallmark ADR of Levodopa/Carbidopa
staining of sheets/clothing
111 terms
Pharmacology
Otic Route
Oral Route
Transdermal Route
Subcutaneous Route
Placed into ear
Into the mouth or stomach
Patch placed onto skin
Injected into the subcutaneous fat layer of the skin
Otic Route
Placed into ear
Oral Route
Into the mouth or stomach
60 terms
Pharmacology
Pharmacology
Herbal Medicine
drugs have several names assigned to t…
Chemical Name (scienticfic name)
Study of drugs and their action on living organisms
herbal medicine, herbalism, and herbal therapy are names for…
chemical name,a generic name (nonproprietary), the official n…
Gives the exact chemical makeup of the drug and placing of th…
Pharmacology
Study of drugs and their action on living organisms
Herbal Medicine
herbal medicine, herbalism, and herbal therapy are names for…
28 terms
Pharmacology
Lineweaver-burk plot
Volume of Distribution
Zero order elimination
First order elimination
1) Km is inversely related to the affinity of an enzyme for…
Vd = (amount of drug in body)/ (plasma drug concentration)... 1…
Rate of drug elimination is independent of its plasma concent…
Rate of drug elimination is a constant fraction, depending on…
Lineweaver-burk plot
1) Km is inversely related to the affinity of an enzyme for…
Volume of Distribution
Vd = (amount of drug in body)/ (plasma drug concentration)... 1…
29 terms
Pharmacology
describe palelets activation steps
Name drugs that works on TXA2, P2Y12,…
what normally activate protease-activa…
what are the component of coagulation…
1- Following vascular injury, platelet adhesion is generally…
TXA2: ASA... P2Y12: Ticlopidine, Clopidogrel, Prasugrel, Ticagre…
Thrombin
describe palelets activation steps
1- Following vascular injury, platelet adhesion is generally…
Name drugs that works on TXA2, P2Y12,…
TXA2: ASA... P2Y12: Ticlopidine, Clopidogrel, Prasugrel, Ticagre…
8 terms
Pharmacology
Draw the neurotransmitters... Sympathetic…
What parts of the neurotransmitter pat…
How does botox work?
Which adrenergic or cholinergic recept…
Sympathetic... -Preganglionic - Acetylcholine... -Postganglionic -…
Mepyramine - Neurotransmitter production (this is what he sai…
It destroys SNAP-25, a docking protein involved in binding ne…
Nicotinic receptors (cholinergic)... (alpha and beta adrenergic…
Draw the neurotransmitters... Sympathetic…
Sympathetic... -Preganglionic - Acetylcholine... -Postganglionic -…
What parts of the neurotransmitter pat…
Mepyramine - Neurotransmitter production (this is what he sai…
13 terms
Pharmacology
PRN
AC
PC
Subcut meds are deposited in the loose…
As needed
Before meals
After meals
Dermis
PRN
As needed
AC
Before meals
378 terms
Pharmacology
Pharmacology
Pharmacotherapy
Phase 1 study
Phase 2 study
The study if the biological effects of chemicals
Clinical pharmacology; branch of pharmacology that deals with…
Pilot study of a potential drug done with a small number of h…
Clinical study of a proposed drug by selected physicians usin…
Pharmacology
The study if the biological effects of chemicals
Pharmacotherapy
Clinical pharmacology; branch of pharmacology that deals with…
55 terms
Pharmacology
__/__ doctor vists result in a Rx
use of drugs for the treatment of dise…
study of drugs, properties and their e…
study of drug absorption, distribution…
2/3
pharmacotherapy
pharmacology
pharmacokinetics
__/__ doctor vists result in a Rx
2/3
use of drugs for the treatment of dise…
pharmacotherapy
55 terms
Pharmacology
nervous system
What is the basic unit of the nervous…
What are the three types of neurons?
Name the parts of a neuron.
the main regulatory and communication system in the animals b…
neuron,
sensory-carries impulses towards the CNS ... associative-carries…
The cell body: has the nucleus and is responsible for maintai…
nervous system
the main regulatory and communication system in the animals b…
What is the basic unit of the nervous…
neuron,
35 terms
pharmacology
falls
Seizure Precautions
Seclusion and Restraints
fire Safety
Prevention of Falls... ◯Complete a fall-risk assessment upon adm…
●Seizure precautions (measures to protect the client from inj…
●In general, seclusion and/or restraints should be ordered fo…
●Fires in health care facilities are usually due to problems…
falls
Prevention of Falls... ◯Complete a fall-risk assessment upon adm…
Seizure Precautions
●Seizure precautions (measures to protect the client from inj…
35 terms
Pharmacology
Pharmacology
Drug
Drug therapy
Medication
The study of drugs that alter the function of living organisms
Any chemical substance that influences living systems
The use of drugs to prevent,diagnose or cure disease process…
Drug given for therapeutic purposes
Pharmacology
The study of drugs that alter the function of living organisms
Drug
Any chemical substance that influences living systems
27 terms
Pharmacology
The nonproprietary name is also known…
The proprietary name is known as the _…
The time course of drug concentrations…
_______ is known as what the drug does…
Generic
Brand
Pharmacokinetics
Pharmacodynamics
The nonproprietary name is also known…
Generic
The proprietary name is known as the _…
Brand
10 terms
Pharmacology
Antagonist
Antibiotics
Concentration
Intrathecal
A drug or chemical that blocks a receptor mediated response
Drugs that inhibit the growth of or kill bacteria.
A measure of the quantity of a substance per unit of volume o…
Refers to administration of a drug into the spinal canal
Antagonist
A drug or chemical that blocks a receptor mediated response
Antibiotics
Drugs that inhibit the growth of or kill bacteria.
Pharmacology
pharmacology
generic name
chemical name
brand name
the action of drugs on humans and the mechanism of drug inter…
the official name of the drug
molecular structure of the drug
name assigned by drug manufacturer
pharmacology
the action of drugs on humans and the mechanism of drug inter…
generic name
the official name of the drug
71 terms
Pharmacology
What drug from the Benzodiazepine clas…
Acts in the limbic system and reticula…
Are drugs which depress or slow down t…
The ___???______ enhance the action of…
Xanax
Diazepam
Hypnotics
Benzodiazepine
What drug from the Benzodiazepine clas…
Xanax
Acts in the limbic system and reticula…
Diazepam
17 terms
Pharmacology
Antacids
cimetidine
ranitidine hydrochloride
femotidine
Trade names: Rolaids, Maalox... -Basic compounds that are used t…
"Sigh-met-a-deen"... Trade name: Peptol, Novocimetine... -Acid-cont…
Trade name: Zantac... -Acid-controlling drug: H2 Antagonist... -Ind…
"fa-moe-ti-deen"... Trade name: Pepcid... -Acid-controlling drug: H…
Antacids
Trade names: Rolaids, Maalox... -Basic compounds that are used t…
cimetidine
"Sigh-met-a-deen"... Trade name: Peptol, Novocimetine... -Acid-cont…
9 terms
pharmacology
Drugs
Oral Administration
Sublingual Administration
Rectal Administration
(medicines) are substances used to prevent or treat a conditi…
Drugs given by mouth and are slowly absorbed into the bloodst…
Drugs placed under the tongue
Drugs are given by rectum when oral administration presents d…
Drugs
(medicines) are substances used to prevent or treat a conditi…
Oral Administration
Drugs given by mouth and are slowly absorbed into the bloodst…
9 terms
Pharmacology
Official name given to the active ingr…
Term for medications that require a pr…
Term that describes the study of drugs…
The patient chart actually belongs to…
Generic name
Legend drugs
Pharmacology
Hospital
Official name given to the active ingr…
Generic name
Term for medications that require a pr…
Legend drugs
41 terms
Pharmacology
anticholinergic
beta blocker
calcium channel blocker
corticosteroid
-kind:atropine... -for heart block/ bradycardia->*result in i…
-decrease HR, BP, contractility, stroke volume->**HR : low…
-inhibit the influx of calcium ions to myocardial and vascula…
*prolonged use... -*inhibit inflammatory process* including ca…
anticholinergic
-kind:atropine... -for heart block/ bradycardia->*result in i…
beta blocker
-decrease HR, BP, contractility, stroke volume->**HR : low…
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