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Study sets matching "pharm"

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Study sets matching "pharm"

152 terms
Pharmacology
Enzyme Kinetics
Enzyme Kinetics (cont)
Enzyme Kinetics (cont x2)
Enzyme Kinetics (cont x3)
Enzyme Kinetics
Enzyme Kinetics (cont)
42 terms
Pharmacology
adverse effect
generic name
Trade name
When approaching pharmacology in gener…
Sn undesirable or harmful effect from a medication
Usually an abbreviated version of the drugs chemical name. It…
created by pharmaceutical companies... aka as the proprietary or…
How does the drug get in the body?... How does the drug move aro…
adverse effect
Sn undesirable or harmful effect from a medication
generic name
Usually an abbreviated version of the drugs chemical name. It…
41 terms
Pharmacology
anticholinergic
beta blocker
calcium channel blocker
corticosteroid
-kind:atropine... -for heart block/ bradycardia->*result in i…
-decrease HR, BP, contractility, stroke volume->**HR : low…
-inhibit the influx of calcium ions to myocardial and vascula…
*prolonged use... -*inhibit inflammatory process* including ca…
anticholinergic
-kind:atropine... -for heart block/ bradycardia->*result in i…
beta blocker
-decrease HR, BP, contractility, stroke volume->**HR : low…
27 terms
Pharmacology
Increased activity by a drug's action
Decreased activity by a drug's action
Injuries
Replacement therapy
Stimulation
Depression or inhibition
Damage over cells which are not specified to a drug's action
Administering molecules that the body lacks
Increased activity by a drug's action
Stimulation
Decreased activity by a drug's action
Depression or inhibition
285 terms
Pharmacology
intrinsic activity
intrinsic activity determines drug ___…
chemical affinity determines drug ____…
T/F. Most drugs are irreversible.
ability of bound drug to activate receptor
efficacy (magnitude of response)
dosage and potency
False
intrinsic activity
ability of bound drug to activate receptor
intrinsic activity determines drug ___…
efficacy (magnitude of response)
70 terms
Pharmacology
Carbachol
Bethanechol
Pilocarpine
Edrophonium
Cholinomimetic... Direct Acting Cholinergic Agonists... Acts on M a…
Cholinomimetic... Direct Acting Cholinergic Agonists... Acts on M r…
Cholinomimetic ... Direct Acting Cholinergic Alkaloid... Acts on ma…
Cholinomimetic ... Reversible AChE inhibitor ... Short Acting (10-2…
Carbachol
Cholinomimetic... Direct Acting Cholinergic Agonists... Acts on M a…
Bethanechol
Cholinomimetic... Direct Acting Cholinergic Agonists... Acts on M r…
506 terms
Pharmacology
Selective Cox-2 inhibitors
Neuroleptic malignant Syndrome
Modafinil
Tetracyclines
eg. celecoxib. ... Cox-2 is an inducible enzyme that is unregul…
adverse reaction to antipsychotic medication characterized by…
first line treatment for narcolepsy. ... Amphetamines are secon…
are teratogenic and can cause fetal bone growth retardation a…
Selective Cox-2 inhibitors
eg. celecoxib. ... Cox-2 is an inducible enzyme that is unregul…
Neuroleptic malignant Syndrome
adverse reaction to antipsychotic medication characterized by…
36 terms
Pharmacology
Absorption
Bioavailability
First-pass hepatic effect
Distribution
factors that affect oral absorption... - pH... - gastric emptying t…
the percentage of the dose reaching the systemic circulation…
A drug may be metabolized by the liver before it reaches the…
- total body water decreases with maturation resulting from a…
Absorption
factors that affect oral absorption... - pH... - gastric emptying t…
Bioavailability
the percentage of the dose reaching the systemic circulation…
156 terms
Pharmacology
drug metabolism
drug metabolism synonyms
hepatic microsomes
without drug metabolsim
collection of biochemical reactions aimed at ultimately elimi…
biotransformation... drug inactivation( not great)... drug detoxifi…
smooth ER in hepatocytes (trabeculated network)... site of drug…
lead to prolonged uncontrolled activity of a given drug... ex-th…
drug metabolism
collection of biochemical reactions aimed at ultimately elimi…
drug metabolism synonyms
biotransformation... drug inactivation( not great)... drug detoxifi…
29 terms
Pharmacology
Alpha Receptor
Beta Receptor
Stereocenter
physiochemical complementarity
Ionic interactions, smaller charged molecules
hydrophobic interactions, large non-polar molecules
carbon atom bonded to 4 different things
how drug is attracted to target, based on charge and bonds
Alpha Receptor
Ionic interactions, smaller charged molecules
Beta Receptor
hydrophobic interactions, large non-polar molecules
38 terms
pharmacology
.. The nurse is explaining to the pati…
. 1. ID: 310993981 Which action should…
The nurse identifies crepitus when exa…
The nurse prepares to change a patient…
Nonspecific drugs require higher doses than specific drugs to…
A Have the client empty her bladder. Correct
B Observe for an asymmetrical Moro (startle) reflex. Correct
A bioavailability.
.. The nurse is explaining to the pati…
Nonspecific drugs require higher doses than specific drugs to…
. 1. ID: 310993981 Which action should…
A Have the client empty her bladder. Correct
11 terms
Pharmacology
Methadone
Barbituates
Benzodiazepines
-chol
Opioid used in the management of withdrawal states... Long Half-…
drugs that *depress the activity of the central nervous syste…
Sedatives are drugs that are intended to relax and calm. Anti…
Muscarinic agonist
Methadone
Opioid used in the management of withdrawal states... Long Half-…
Barbituates
drugs that *depress the activity of the central nervous syste…
58 terms
Pharmacology
Pharmacokinetics
Pharmacodynamics
Pharmacotherapeutics
Adverse effects
The study of how drugs are absorbed, distributed, metabolized…
The study of how drugs are used by the body
The study of how the client responds to the drug
results in symptoms so severe that it is necessary to reduce…
Pharmacokinetics
The study of how drugs are absorbed, distributed, metabolized…
Pharmacodynamics
The study of how drugs are used by the body
129 terms
Pharmacology
Larger to smaller
Smaller to larger
1 kg =
1 L =
3 to the right or multiply
3 to the left or divide
1000 g
1000 mL
Larger to smaller
3 to the right or multiply
Smaller to larger
3 to the left or divide
119 terms
Pharmacology
What are some disadvantages to using t…
AD
AS
AU
limited penetration on skin and the animal can lick off the m…
Right ear
Left ear
Both ears
What are some disadvantages to using t…
limited penetration on skin and the animal can lick off the m…
AD
Right ear
87 terms
Pharmacology
Symptomatic therapy is:
With regard to drugreceptor binding
Concerning renal excretion
Circle the group of antibacterials wit…
Treating the symptoms (fever, cough)
A competitive antagonist has no intrinsic activity
-A lipid soluble, filtered drug will likely be reabsorbed by…
Makrolides, tetracyclines, sulfanoamides, amphenicoles
Symptomatic therapy is:
Treating the symptoms (fever, cough)
With regard to drugreceptor binding
A competitive antagonist has no intrinsic activity
50 terms
Pharmacology
Pharmacodynamics
Pharmacokinetics
Distribution
Biotransformation
The way in which a medication produces the response intended,…
The study of the metabolism and action of medications within…
Blood is the primary distribution vehicle. Placental and brai…
The chemical alteration of chemicals such as nutrients, amino…
Pharmacodynamics
The way in which a medication produces the response intended,…
Pharmacokinetics
The study of the metabolism and action of medications within…
141 terms
pharmacology
Alprazolam (Xanax)... CLASS
DIAZEPAM (VALIUM) CLASS
Lorazepam (Ativan) CLASS
Midazolam (Versed) CLASS
ANXIOLYTIC/HYPNOTIC
ANXIOLYTIC/HYPNOTIC
ANXIOLYTIC/HYPNOTIC
ANXIOLYTIC/HYPNOTIC
Alprazolam (Xanax)... CLASS
ANXIOLYTIC/HYPNOTIC
DIAZEPAM (VALIUM) CLASS
ANXIOLYTIC/HYPNOTIC
22 terms
Pharmacology
Rights...
Pharmacology
CCB
Pharmacodynamics
Patient,Route,time,dosage, documentation, medication, effects…
Study of biological effects of chemicals
Calcium channel blocker-cardiac
Drug effects body
Rights...
Patient,Route,time,dosage, documentation, medication, effects…
Pharmacology
Study of biological effects of chemicals
30 terms
Pharmacology
aer/o
alges/o
bronch/o
chem/o
air
sensitivity to pain
bronchial tube
drug
aer/o
air
alges/o
sensitivity to pain
pharmacology
administration of proton pump
cirrhosis of liver
subcutaneous low weight heparin
nitroglyercide patch
ask client about gastrointestinal pain
monitor serum ammonia levels
lateral abdomina
take patch off at night
administration of proton pump
ask client about gastrointestinal pain
cirrhosis of liver
monitor serum ammonia levels
152 terms
Pharmacology
Enzyme Kinetics
Enzyme Kinetics (cont)
Enzyme Kinetics (cont x2)
Enzyme Kinetics (cont x3)
Enzyme Kinetics
Enzyme Kinetics (cont)
14 terms
Pharmacology
kasdflkasjdfl
skfljasflkj
digoxin (Lanoxin)
Tyramine
alkjfaslfjasdl;f
asdlkfjasl;fkja
Cardiac Stimulant
a compound that occurs naturally in cheese and other foods an…
kasdflkasjdfl
alkjfaslfjasdl;f
skfljasflkj
asdlkfjasl;fkja
152 terms
Pharmacology
Enzyme Kinetics
Enzyme Kinetics (cont)
Enzyme Kinetics (cont x2)
Enzyme Kinetics (cont x3)
Enzyme Kinetics
Enzyme Kinetics (cont)
8 terms
Pharmacology
Finasteride/propecia
Tamsulosin
Fioricet (Butalbital/Acetaminophen/Caf…
Meclizine
Tx: BPH. alopecia... Pathway: 5 alpha reductase inhibitor.... class:
tx: BPH, prostates hyperplasia... Pathway: alpha blocker... Class:
tx: Headaches... Pathway: Agoinist for GABA receptors which is a…
tx: vertigo, n/v or dizziness... pathway: antihistamine ... class:…
Finasteride/propecia
Tx: BPH. alopecia... Pathway: 5 alpha reductase inhibitor.... class:
Tamsulosin
tx: BPH, prostates hyperplasia... Pathway: alpha blocker... Class:
18 terms
Pharmacology
6 rights of Medication Administration
6 rights of Medication Administration
Routes of Administration
Enteral Administration
M & D, T R P, D
Right: Medication; Dosage; Time; Route; Patient; Documentation
Enteral, Percutaneous, Parenteral
Powders, Pills, Tablets, Liquids/ Suspensions, Suppositories
6 rights of Medication Administration
M & D, T R P, D
6 rights of Medication Administration
Right: Medication; Dosage; Time; Route; Patient; Documentation
11 terms
Pharmacology
Multiplying Fractions
Dividing Fractions
1 Gram is equal to
Medication Calculation formula is D/H…
Step 1: Multiply the two numerators... Step 2: Multiply the two…
Step 1: Flip the second fraction (place denominator on top an…
1000 milligrams
Example: 25mg ordered, 50mg/mL on hand... D= 25mg... H = 50mg... Q= 1…
Multiplying Fractions
Step 1: Multiply the two numerators... Step 2: Multiply the two…
Dividing Fractions
Step 1: Flip the second fraction (place denominator on top an…
78 terms
Pharmacology
Absorption of Pediatric Drugs
Distribution of Pediatric Drugs
Metabolism of Pediatric Drugs
Excretion of Pediatric Drugs
The pH in infant stomachs are decreased until ~3-4 months old…
Body weight is 70-75% water therefore they require higher dos…
This is very DIFFICULT to predict. The mothers drug history h…
A child's kidneys are not mature until age 1. Prior to that e…
Absorption of Pediatric Drugs
The pH in infant stomachs are decreased until ~3-4 months old…
Distribution of Pediatric Drugs
Body weight is 70-75% water therefore they require higher dos…
116 terms
Pharmacology
diffusion rate
Drugs only absorbed when they are
most drugs are
henderson hasselbalch equation
=-DAK(Cout-Cin)/CX... D:diffusion inversely related to size of d…
NONionized and therefore also have a higher lipid solubility
weak electrolytes (can be charged or uncharged)
blood pH is 7.4... gastric pH is 1.4
diffusion rate
=-DAK(Cout-Cin)/CX... D:diffusion inversely related to size of d…
Drugs only absorbed when they are
NONionized and therefore also have a higher lipid solubility
82 terms
Pharmacology
ethical drug
generic
inscription
patent medicine
a drug that requires a prescription?
drugs sold without a brandname or trademark?
On a prescription, the name and quantity of a drug?
Drug that can be obtained without a prescription, also called…
ethical drug
a drug that requires a prescription?
generic
drugs sold without a brandname or trademark?
49 terms
pharmacology
phase 1
phase 2
phase 3
phase 4
toxicity and determine MTD
response rate and toxicity
efficacy v standard
post-marketing... looking for signals that may not have been pic…
phase 1
toxicity and determine MTD
phase 2
response rate and toxicity
37 terms
Pharmacology
pharmacokinetics
pharmacodynamics
pharmacotherapeutics
generic name
what the body does to the drug
what the drug does to the body
the use of drugs in the treatment of disease
most common drug name
pharmacokinetics
what the body does to the drug
pharmacodynamics
what the drug does to the body
232 terms
Pharmacology
Pharmaceutic Phases
4 stages of Pharmacokinetics
1. Absorption (and factors)
Why do fatty foods increase absorption?
1. Absorption 2. Distribution 3. Metabolism 4. Excretion
Movement of drugs from site of administration into vascular b…
gut motility slows down, more time for med absorption
Pharmaceutic Phases
4 stages of Pharmacokinetics
1. Absorption 2. Distribution 3. Metabolism 4. Excretion
40 terms
pharmacology
Lists the parts of the Nervous system.…
The ANS all have distal ______, and my…
The ANS has what two neurotransmitters?
NE has how many types of receptors?
the NS is broken into the CNS and PNS. The CNS includes the b…
ganglia, PREganglion, POST-, NON-myelinated, myelinated.
Acetylcholine (ACH) and Norepinephrine (NE).
5: alpha 1, 2, beta 1-3.
Lists the parts of the Nervous system.…
the NS is broken into the CNS and PNS. The CNS includes the b…
The ANS all have distal ______, and my…
ganglia, PREganglion, POST-, NON-myelinated, myelinated.
110 terms
Pharmacology
Alpha Blocker Adverse Effects
Beta Blocker Use
ED 50
Agonist
Orthostatic hypotension, reflex tachycardia (barorreceptors s…
Agina pectoris, hypertension, cardiac disrhythmias, MI, heart…
Lowest dose needed to produce effect in 50% of population
Binds to receptor and produces effect. Endogenous e.g. NE, Ep…
Alpha Blocker Adverse Effects
Orthostatic hypotension, reflex tachycardia (barorreceptors s…
Beta Blocker Use
Agina pectoris, hypertension, cardiac disrhythmias, MI, heart…
30 terms
Pharmacology
Allergic reaction
Adverse reaction
anaphylactic shock
angioedema
Immediate hypersensitive reaction by the immune system; it pr…
undesirable drug effect
sudden, server hypersensitivity reaction with symptoms that p…
localized wheals or swelling in the subcutaneous tissue or mu…
Allergic reaction
Immediate hypersensitive reaction by the immune system; it pr…
Adverse reaction
undesirable drug effect
Pharmacology
Etiologic Classifications
Congenital
Degenerative
Iatrogenic
...
born w/ it
break down of body
caused by medical portion
Etiologic Classifications
...
Congenital
born w/ it
8 terms
Pharmacology
Antibiotic (Amoxil, Cipro, Rocephin)
Antihistamine (Allegra, Claritan, Bena…
Antitussive (Hycodan, Vicks Formula 44…
Bronchodilator (Proventil, Ventolin, A…
Kills bacteria
Blocks histamine released during allergy attack
Relieves urge to cough
Relaxes bronchospasms, treats asthma
Antibiotic (Amoxil, Cipro, Rocephin)
Kills bacteria
Antihistamine (Allegra, Claritan, Bena…
Blocks histamine released during allergy attack
166 terms
Pharmacology
STUDY CONSIDERATIONS
Pharmaceutic Phases
Pharmacokinetics
4 Characteristics of Pharmacokinetics
INDICATIONS - why giving certain products?... INTERACTIONS... MONIT…
movement of drugs within the body
1. Absorption... 2. Distribution... 3. Metabolism (AKA biotransform…
STUDY CONSIDERATIONS
INDICATIONS - why giving certain products?... INTERACTIONS... MONIT…
Pharmaceutic Phases
13 terms
pharmacology
Epinephrine
Benadryl
Afrin nasal spray
Flonase
Epinephrine
Benadryl
73 terms
Pharmacology
Alpha1 stimulation
Alpha2 stimulation
Beta1 stimulation
Beta2 stimulation
-Increases cardiac contractility, vasoconstriction.... -Dilates…
-Inhibits norepenephrine release... -Promotes vasodilation and d…
-increases cardiac contractility, Heart rate... -Increases renin…
-Promotes GI relaxation... -Bronchodilation... -Increases blood flo…
Alpha1 stimulation
-Increases cardiac contractility, vasoconstriction.... -Dilates…
Alpha2 stimulation
-Inhibits norepenephrine release... -Promotes vasodilation and d…
30 terms
Pharmacology
Neurogenic bladder
Priapism
urge incontinence
stress inconrinence
impaired bladder function caused by a nervous system abnormal…
prolonged, painful penile erection
strong, sudden need to void due to the bladder spasm or contr…
losing urine without meaning to during physical activity
Neurogenic bladder
impaired bladder function caused by a nervous system abnormal…
Priapism
prolonged, painful penile erection
96 terms
Pharmacology
Pharmacology
Drug
Pharmacokinetics
Inhalation
The study of drugs and their origin, nature, properties, and…
A chemical agent used in the prevention, treatment, or diagno…
The method by which drugs are absorbed, distributed, metaboli…
means of bringing medication or substances to the respiratory…
Pharmacology
The study of drugs and their origin, nature, properties, and…
Drug
A chemical agent used in the prevention, treatment, or diagno…
21 terms
Pharmacology
Therapeutic Response
Side Effects
Adverse Reactions
Idiosyncratic Effects
Desired action of a drug; used to classify medications; deter…
Effects on body system other than the intended target; leads…
Most severe reactions; hypersensitivity reactions; idiosyncra…
Causes and effects that weren't planned or that were unexpected
Therapeutic Response
Desired action of a drug; used to classify medications; deter…
Side Effects
Effects on body system other than the intended target; leads…
447 terms
Pharmacology
Water vs. Fat Soluble
Thiamine (B1)
Cobalamin (B12)
Folate (B9)
Water Soluble = B, C... Fat Soluble = DAKE... Fat soluble vitamins…
Most common deficiency... - alcoholics, elderly (poor nutrition)…
Causes of deficiency:... - pernicious anemia... - ileum resection... -…
Causes of deficiency:... - DHFR inhibitor drugs (methotrexate, s…
Water vs. Fat Soluble
Water Soluble = B, C... Fat Soluble = DAKE... Fat soluble vitamins…
Thiamine (B1)
Most common deficiency... - alcoholics, elderly (poor nutrition)…
35 terms
Pharmacology
acetaminophen (Tylenol)
enteric coated aspirin (ECASA)
oxycodone/APAP (Percocet)
morphine sulfate (Duramorph, MS Contin)
Antipyretic/Analgesic/ although a weak inhibitor of the cyclo…
Buffered form of ASA that is easier on stomach in patients ta…
Category: Opiate analgesic/antipyretic, Use: Moderate to seve…
Opioid used to treat severe pain. Sometimes used as an anesth…
acetaminophen (Tylenol)
Antipyretic/Analgesic/ although a weak inhibitor of the cyclo…
enteric coated aspirin (ECASA)
Buffered form of ASA that is easier on stomach in patients ta…
98 terms
Pharmacology
Respiratory stimulants (analeptics)
Amphetamines (anorexiant)
Analgesic Agonist (opioids)
Narcotic Antagonist
PROTOTYPE: Doxapram (dopram) USES: stimulate breathing ACTION…
PROTOTYPE: Dexedrine (dextramphetamine) USE: to treat narcole…
PROTOTYPE: Morphine Sulfate ACTION: binds to opiate receptor…
PROTOTYPE: Narcan (naloxone hydrochloride) USE: after surgery…
Respiratory stimulants (analeptics)
PROTOTYPE: Doxapram (dopram) USES: stimulate breathing ACTION…
Amphetamines (anorexiant)
PROTOTYPE: Dexedrine (dextramphetamine) USE: to treat narcole…
12 terms
Pharmacology
Pharmacology
Drug
Terminology
Sources of drugs
Study of drugs
Any substance going into the body, has an effect on compositi…
Presentation - The form and strength of the drug... Therapeutic…
Naturally occurring... Derived from Animals (hormones)... Synthetic
Pharmacology
Study of drugs
Drug
Any substance going into the body, has an effect on compositi…
592 terms
Pharmacology
Name the two terms associated with the…
____ of the drug is plotted where the…
____ of a drug may exhibit is plotted…
the amount of a drug to produce an eff…
therapeutic range... maximum response
thraputic range
maximum response
potency
Name the two terms associated with the…
therapeutic range... maximum response
____ of the drug is plotted where the…
thraputic range
13 terms
Pharmacology
Pharmacology
Drug
Terminology
Sources of drugs
Study of drugs
Any substance going into the body, has an effect on compositi…
Presentation - The form and strength of the drug... Therapeutic…
Naturally occurring... Derived from Animals (hormones)... Synthetic
Pharmacology
Study of drugs
Drug
Any substance going into the body, has an effect on compositi…
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