Study sets matching "pharm"

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Study sets matching "pharm"

219 terms
Pharmacology
Michaelis-Menten kinetics
Most enzymatic reactions follow a *hyp…
Lineweaver-Burk plot... The further to…
Enzyme inhibition... Reversible competiti…
Km = [S] at 1/2[Vmax], where [S] = concentration of substrate…
Most enzymatic reactions follow a ________ curve (i.e., _____…
_______ plot: increase y intercept, decrease Vmax... The furthe…
Enzyme inhibition:... __________ inhibitors cross eachother comp…
Michaelis-Menten kinetics
Km = [S] at 1/2[Vmax], where [S] = concentration of substrate…
Most enzymatic reactions follow a *hyp…
Most enzymatic reactions follow a ________ curve (i.e., _____…
pharmacology
the action of phrmacokinetics
metabolism, excretion
absorption
passive diffusion
absorption, distribution, metabolism, excretion
drug elimination or clearance mechanism
time the drug enters the body to the time it enters the bodys…
movement of a drug from an area of higher concentration to on…
the action of phrmacokinetics
absorption, distribution, metabolism, excretion
metabolism, excretion
drug elimination or clearance mechanism
101 terms
Pharmacology
Pharmacology
Pharmacokinetics associated with
Pharmacodynamics associated with
Before a drug can begin to exert any e…
. the study of drugs (chemicals) and their interactions with…
. ADME
. Receptor binding... . Signal transduction ... . Physiologic effect
. absorbed
Pharmacology
. the study of drugs (chemicals) and their interactions with…
Pharmacokinetics associated with
. ADME
38 terms
pharmacology
.. The nurse is explaining to the pati…
. 1. ID: 310993981 Which action should…
The nurse identifies crepitus when exa…
The nurse prepares to change a patient…
Nonspecific drugs require higher doses than specific drugs to…
A Have the client empty her bladder. Correct
B Observe for an asymmetrical Moro (startle) reflex. Correct
A bioavailability.
.. The nurse is explaining to the pati…
Nonspecific drugs require higher doses than specific drugs to…
. 1. ID: 310993981 Which action should…
A Have the client empty her bladder. Correct
21 terms
Pharmacology
Agonists
Endogenous drugs
exogenous drugs
Ach agonist
-drugs can act as these... - act as neurotransmitters that bind…
-ex: endorphine... -naturally occurring
- ex; heroine ... - drugs put into body
- nicotine
Agonists
-drugs can act as these... - act as neurotransmitters that bind…
Endogenous drugs
-ex: endorphine... -naturally occurring
36 terms
Pharmacology
Pharmacology
Pharmadynamics
receptors
agonists
The study of drugs their actions on living organisims
The study of drugs interactions including the drug receptors…
sites on the cells where chemical bonding of drugs occurs are…
drugs that stimulate a response at a receptor site
Pharmacology
The study of drugs their actions on living organisims
Pharmadynamics
The study of drugs interactions including the drug receptors…
8 terms
Pharmacology
Shock, cardiac arrest and anaphylaxis…
Antianxiety agents
Digoxin (lanoxin)
SSRI
Norepinephrine: H/A, HTN... Dopamine: increased ocular pressure,…
Chlordiazepoxide (librium)- both: hypotension,↓ wbc (agranulo…
indic: HF, a fib, paroxysmal atrial tachy... action: ↑ calcium i…
Sertraline (zoloft)... Fluoxetine (Prozac)... Paroxetine (paxil)... a…
Shock, cardiac arrest and anaphylaxis…
Norepinephrine: H/A, HTN... Dopamine: increased ocular pressure,…
Antianxiety agents
Chlordiazepoxide (librium)- both: hypotension,↓ wbc (agranulo…
168 terms
Pharmacology
Km
Vmax
Hyperbolic curve
Sigmoid curve
Inversely related to the affinity of the enzyme for its subst…
Directly proportional to the enzyme concentration
Michaelis Menten Kinetics
Cooperative kinetics
Km
Inversely related to the affinity of the enzyme for its subst…
Vmax
Directly proportional to the enzyme concentration
pharmacology
anesthetic agents
antibacterials
antifungals
antihistamines
reduce pain and discomfort
prevent and treat bacterial growth , such as triple antibioti…
treat fungal infections
lessen itching by reducing an allergic response
anesthetic agents
reduce pain and discomfort
antibacterials
prevent and treat bacterial growth , such as triple antibioti…
31 terms
Pharmacology
Half-live
Agonists
Antagonist
Nonspecific Drug
The half-life of a drug is the time it takes for one half of…
Drugs that produce a response
Drugs that block a response
Drugs that affect various sites are nonspecific drugs and hav…
Half-live
The half-life of a drug is the time it takes for one half of…
Agonists
Drugs that produce a response
10 terms
Pharmacology
DEA
Administer
Dispense
Narcotic
Demise
To manage , to conduct , as in business
To distribute ; to deal out in portions .
A drug capable of producing sleep and relieving pain or induc…
DEA
Demise
Administer
To manage , to conduct , as in business
78 terms
Pharmacology
****Antibiotics****
Penicillin
Beta Lactamase Inhibitors
Aminopenicillin Mechanism
...
(picmonic)
(picmonic)
(picmonic)
****Antibiotics****
...
Penicillin
(picmonic)
Pharmacology
Pharmacology
Kd
Drug
Medicine
the study of the effects of chemical substances on the functi…
Dissociation constant, the concentration of a ligand that giv…
A chemical substance of known structure which produces a biol…
A chemical preparation, which contains one or more drugs, adm…
Pharmacology
the study of the effects of chemical substances on the functi…
Kd
Dissociation constant, the concentration of a ligand that giv…
150 terms
Pharmacology
Bioavailability (F)
Bioavailability of IV drugs?
Volume of distribution
Clearance
Fraction of drug that enters systemic circulation unchanged
100%
Vd = Dose / (Plasma Drug conc.)
Volume of plasma that is cleared of drug per unit time... CL…
Bioavailability (F)
Fraction of drug that enters systemic circulation unchanged
Bioavailability of IV drugs?
100%
92 terms
Pharmacology
Cyclosporine
Tacrolimus
Sirolimus (Rapamycin)
Daclizumab, basiliximab
Immunosuppressant... Calcinuerin inhibitor that blocks cyclop…
Immunosuppressant... Calcinuerin inhibitor that binds FK506 b…
Immunosuppressant used in Kidney transplant rejection prophyl…
Immunosuppressant monoclonal antibodies that Block IL-2R... U…
Cyclosporine
Immunosuppressant... Calcinuerin inhibitor that blocks cyclop…
Tacrolimus
Immunosuppressant... Calcinuerin inhibitor that binds FK506 b…
70 terms
Pharmacology
ADHD - Preferred drugs
Alcohol Withdrawal - Preferred drugs
Bipolar disorder - Preferred drugs
Bulimia - Preferred drugs
Methylpenidate (stimulants)
Chlordiazepoxide, Lorazepam, Diazepam (long-acting benzodia…
Lithium, Valproic Acid, atypical antipsychotics
SSRIs
ADHD - Preferred drugs
Methylpenidate (stimulants)
Alcohol Withdrawal - Preferred drugs
Chlordiazepoxide, Lorazepam, Diazepam (long-acting benzodia…
57 terms
Pharmacology
Cyclosporine - Mechanism
Cyclosporine - Use
Cyclosporine - Toxicity
Tacrolimus (FK506) - Mechanism
Calcineurin inhibitor;... Binds Cyclophilin, blocks T-cell…
Transplant rejection prophylaxis, psoriasis, rheumatoid arthr…
Nephrotoxicity, hypertension, hyperlipidemia, neurotoxicity…
Calcineurin inhibitor;... Binds FK506 binding protein (FKBP…
Cyclosporine - Mechanism
Calcineurin inhibitor;... Binds Cyclophilin, blocks T-cell…
Cyclosporine - Use
Transplant rejection prophylaxis, psoriasis, rheumatoid arthr…
31 terms
Pharmacology
Pharmacodynamics
Pharmacokinetics
xenobiotic
toxicant
action of drugs
movement of drugs
foreign substance taken into the body
substances that produce adverse (bad impact) biological effect
Pharmacodynamics
action of drugs
Pharmacokinetics
movement of drugs
152 terms
Pharmacology
Enzyme Kinetics
Enzyme Kinetics (cont)
Enzyme Kinetics (cont x2)
Enzyme Kinetics (cont x3)
Enzyme Kinetics
Enzyme Kinetics (cont)
196 terms
Pharmacology
Potency
Efficacy
Half-life
Routes of drug administration
A function of the amount of a drug to produce an effect... Pote…
Maximum intensity of effect or response that can be produced…
Equals half the amount of time for a drug to "fall" to half o…
Affects both onset (the time it takes for the drug to have an…
Potency
A function of the amount of a drug to produce an effect... Pote…
Efficacy
Maximum intensity of effect or response that can be produced…
42 terms
Pharmacology
adverse effect
generic name
Trade name
When approaching pharmacology in gener…
Sn undesirable or harmful effect from a medication
Usually an abbreviated version of the drugs chemical name. It…
created by pharmaceutical companies... aka as the proprietary or…
How does the drug get in the body?... How does the drug move aro…
adverse effect
Sn undesirable or harmful effect from a medication
generic name
Usually an abbreviated version of the drugs chemical name. It…
Pharmacology
Adrenergic
amino salicylates
anesthetics
antiarrhythmic
used to dilate the pupils, increase heart rate strengthen hea…
help treat inflammation
reduce sensation of pain
to treat arrhythmias
Adrenergic
used to dilate the pupils, increase heart rate strengthen hea…
amino salicylates
help treat inflammation
118 terms
Pharmacology
Calcium channel blockers
Hydralazine
Tx hypertensive emergency
Nitroglycerine
Dihydropyridine: amlodipine, nifedipine... Non-dihydro: diltiaze…
Hypertension in pregnancy... Incr. cGMP > vasodilates arterioles…
Nitroprusside... cGMP > NO
Angina... Incr NO > cGMP > dilate VEINS > decr preload
Calcium channel blockers
Dihydropyridine: amlodipine, nifedipine... Non-dihydro: diltiaze…
Hydralazine
Hypertension in pregnancy... Incr. cGMP > vasodilates arterioles…
239 terms
Pharmacology
Zero-order elimination
Notable drugs with zero-order eliminat…
First-order elimination
Vmax
Constant amount of drug eliminated per unit of time... Eliminati…
Phenytoin... Ethanol... Aspirin... "A PEA has zero calories"
Constant fraction of drug eliminated per unit of time... Elimina…
Point of enzyme saturation indicating maximum reaction rate
Zero-order elimination
Constant amount of drug eliminated per unit of time... Eliminati…
Notable drugs with zero-order eliminat…
Phenytoin... Ethanol... Aspirin... "A PEA has zero calories"
70 terms
Pharmacology
Carbachol
Bethanechol
Pilocarpine
Edrophonium
Cholinomimetic... Direct Acting Cholinergic Agonists... Acts on M a…
Cholinomimetic... Direct Acting Cholinergic Agonists... Acts on M r…
Cholinomimetic ... Direct Acting Cholinergic Alkaloid... Acts on ma…
Cholinomimetic ... Reversible AChE inhibitor ... Short Acting (10-2…
Carbachol
Cholinomimetic... Direct Acting Cholinergic Agonists... Acts on M a…
Bethanechol
Cholinomimetic... Direct Acting Cholinergic Agonists... Acts on M r…
Pharmacology
drug metabolism
drug metabolism synonyms
hepatic microsomes
without drug metabolsim
collection of biochemical reactions aimed at ultimately elimi…
biotransformation... drug inactivation( not great)... drug detoxifi…
smooth ER in hepatocytes (trabeculated network)... site of drug…
lead to prolonged uncontrolled activity of a given drug... ex-th…
drug metabolism
collection of biochemical reactions aimed at ultimately elimi…
drug metabolism synonyms
biotransformation... drug inactivation( not great)... drug detoxifi…
29 terms
Pharmacology
Alpha Receptor
Beta Receptor
Stereocenter
physiochemical complementarity
Ionic interactions, smaller charged molecules
hydrophobic interactions, large non-polar molecules
carbon atom bonded to 4 different things
how drug is attracted to target, based on charge and bonds
Alpha Receptor
Ionic interactions, smaller charged molecules
Beta Receptor
hydrophobic interactions, large non-polar molecules
58 terms
Pharmacology
Pharmacokinetics
Pharmacodynamics
Pharmacotherapeutics
Adverse effects
The study of how drugs are absorbed, distributed, metabolized…
The study of how drugs are used by the body
The study of how the client responds to the drug
results in symptoms so severe that it is necessary to reduce…
Pharmacokinetics
The study of how drugs are absorbed, distributed, metabolized…
Pharmacodynamics
The study of how drugs are used by the body
Pharmacology
Lipitor
Synthroid
Glucophage
Nexium
Atorvastatin... Cholesterol
Levothyroxine
Metforming
Esomeprazole
Lipitor
Atorvastatin... Cholesterol
Synthroid
Levothyroxine
Pharmacology
A nurse is administering donepezil (Ar…
A nurse is caring for an older adult c…
A nurse is providing teaching to a cli…
A nurse is teaching a client who is to…
Dyspnea
B. 0.9% sodium chloride 1 L IV infused over 4hr. Vital signs…
I should let my dentist know I'm taking this medication.
Change positions slowly
A nurse is administering donepezil (Ar…
Dyspnea
A nurse is caring for an older adult c…
B. 0.9% sodium chloride 1 L IV infused over 4hr. Vital signs…
Pharmacology
pharmacology
drug
medicine
side effect
study of all drugs, their properties, how they react with eac…
substance that can change life's processes
used to treat diseases
unintended result
pharmacology
study of all drugs, their properties, how they react with eac…
drug
substance that can change life's processes
41 terms
Pharmacology
Apothecary system
Clarks rule
Denominator
Fraction bar
Oldest system of measurement
Based on the weight of the child
Bottom number of a fraction
Separates the numerator and denominator
Apothecary system
Oldest system of measurement
Clarks rule
Based on the weight of the child
54 terms
pharmacology
DRUG DOSAGE MEANS
PHARMACOLOGY MEANS
TO ADMINISTER A DRUG MEANS TO
OTC
the amount of medication in a single dose
study of the drugs,their uses, and their interations in livin…
GIVE THAT MEDICATION
OVER THE COUNTER
DRUG DOSAGE MEANS
the amount of medication in a single dose
PHARMACOLOGY MEANS
study of the drugs,their uses, and their interations in livin…
Pharmacology
Methotrexate toxicity
Treatment for MTX overdose
Colchicine pharma
Colchicine mechanism
- folate is needed to make purines... - MTX looks just lik…
The patient is given:... - IV fluids... - *Bicarbonate to alkalin…
Volume of distribution: *2-12 L/kg (as much as 20 L/kg in ove…
it inhibits microtubules... so in a overdose histo you may…
Methotrexate toxicity
- folate is needed to make purines... - MTX looks just lik…
Treatment for MTX overdose
The patient is given:... - IV fluids... - *Bicarbonate to alkalin…
Pharmacology
Ondansetron
Dexamethasone
Metoclopropamide
Loperamide
Zofran
Decadron
Reglan
Imodium
Ondansetron
Zofran
Dexamethasone
Decadron
81 terms
Pharmacology
Drug Dosage
Pharmacology
To administer a drug
OTC
Amount of medication in a single dose
Study of drugs, their uses, and their interactions in living…
Give that medication
Over the Counter
Drug Dosage
Amount of medication in a single dose
Pharmacology
Study of drugs, their uses, and their interactions in living…
Pharmacology
pharmacology
pharmacokinetics
A drug has to pass the blood brain bar…
absorption
study of drugs
movement of the drugs through the circulatory system, across…
the CNS
the means by which the drug enters the circulatory system
pharmacology
study of drugs
pharmacokinetics
movement of the drugs through the circulatory system, across…
404 terms
Pharmacology
What is the cycle of pain?
What are the management strategies for…
what is the target area of non-opioid…
what is the target of local anesthetic?
when you have an injury to blood vessel, the release of plasm…
a. desensitization of nerves... b. dentinal tubules coverage... - p…
combatting the effects of peripheral tissue injury such as bl…
block the transmission of nociceptive message through the ner…
What is the cycle of pain?
when you have an injury to blood vessel, the release of plasm…
What are the management strategies for…
a. desensitization of nerves... b. dentinal tubules coverage... - p…
pharmacology
Which member of the surgical tema must…
List the five rights of medication adm…
Medication labels must contain all of…
Improper or inadequate labeling of med…
The circulator
Right drug, right dose, right route, right patient, right time
contraindications
malpractice
Which member of the surgical tema must…
The circulator
List the five rights of medication adm…
Right drug, right dose, right route, right patient, right time
Pharmacology
anticholinergic
beta blocker
calcium channel blocker
corticosteroid
-kind:atropine... -for heart block/ bradycardia->*result in i…
-decrease HR, BP, contractility, stroke volume->**HR : low…
-inhibit the influx of calcium ions to myocardial and vascula…
*prolonged use... -*inhibit inflammatory process* including ca…
anticholinergic
-kind:atropine... -for heart block/ bradycardia->*result in i…
beta blocker
-decrease HR, BP, contractility, stroke volume->**HR : low…
PHARMACOLOGY
substance
synthesize
pharmacist
pharmacy
vật chất
synthesized chemical substances in the laboratory... tổng hợp
drugs are dispensed (phân phối) by a pharmacist
a pharmacist's shop or store ... hiệu thuốc
substance
vật chất
synthesize
synthesized chemical substances in the laboratory... tổng hợp
82 terms
Pharmacology
Oral medicine
PO
NPO
PRN
Given by mouth
Orally
Nothing orally
As needed
Oral medicine
Given by mouth
PO
Orally
52 terms
Pharmacology
Pharmacology
Endogenous Drugs
Poisons
Toxins
The study of substances that interact with living systems thr…
Drugs that produce normal body processes, such as hormones.
Drugs that have almost exclusively harmful effects.
Poisons of biological origins, usually synthesised by plants…
Pharmacology
The study of substances that interact with living systems thr…
Endogenous Drugs
Drugs that produce normal body processes, such as hormones.
pharmacology
antiemetic
antidiarrheal
laxative
antiacid
vomiting
diarrhea
constipation
gas
antiemetic
vomiting
antidiarrheal
diarrhea
Pharmacology
Absorption
Acromion Process
Action
Administer
Passage of a substance through some surface of the body into…
An extension of the shoulder blade
How a drug acts in the body
To instill a drug onto the body of a patient
Absorption
Passage of a substance through some surface of the body into…
Acromion Process
An extension of the shoulder blade
87 terms
Pharmacology
Subscription
Superscription
Inscription
Signature
Contains directions to the pharmacist to include the size of…
Includes the date, patient's name, address, and the Rx symbol
The name of the drug and amount (strength)
Refers to the patient's instructions, usually following sig:
Subscription
Contains directions to the pharmacist to include the size of…
Superscription
Includes the date, patient's name, address, and the Rx symbol
17 terms
Pharmacology
Effectiveness
Safety
Selectivity
Reversible Action
An effective drug is one that elicits the responses for which…
A safe drug is defined as one that cannot produce harmful eff…
A selective drug is defined as one that elicits only the resp…
For most drugs, it is important that effects be reversible. T…
Effectiveness
An effective drug is one that elicits the responses for which…
Safety
A safe drug is defined as one that cannot produce harmful eff…
27 terms
Pharmacology
Increased activity by a drug's action
Decreased activity by a drug's action
Injuries
Replacement therapy
Stimulation
Depression or inhibition
Damage over cells which are not specified to a drug's action
Administering molecules that the body lacks
Increased activity by a drug's action
Stimulation
Decreased activity by a drug's action
Depression or inhibition
Pharmacology
Chemotherapy
Guidelines: Meningitis
beta-lactams
Penicillins
• The use of any chemical agents to treat disease... • Chemother…
• Common agents... o adults... • S. pneumoniae (~60%)... • N. meningit…
• Contain β-lactam ring... • inhibit cell wall synthesis by bloc…
picture
Chemotherapy
• The use of any chemical agents to treat disease... • Chemother…
Guidelines: Meningitis
• Common agents... o adults... • S. pneumoniae (~60%)... • N. meningit…
Pharmacology
Pharmacology
Pharmacologynamic
Agonist
Antagonist
Science of drug including there ingredients
Processed by medicine work on body
Stimulate of receptor
Bind to receptor or block
Pharmacology
Science of drug including there ingredients
Pharmacologynamic
Processed by medicine work on body
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