Study sets matching "pharma"

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Study sets matching "pharma"

Pharmacology
6 rights of Medication Administration
6 rights of Medication Administration
Routes of Administration
Enteral Administration
M & D, T R P, D
Right: Medication; Dosage; Time; Route; Patient; Documentation
Enteral, Percutaneous, Parenteral
Powders, Pills, Tablets, Liquids/ Suspensions, Suppositories
6 rights of Medication Administration
M & D, T R P, D
6 rights of Medication Administration
Right: Medication; Dosage; Time; Route; Patient; Documentation
36 terms
Pharmacology
Absorption
Bioavailability
First-pass hepatic effect
Distribution
factors that affect oral absorption... - pH... - gastric emptying t…
the percentage of the dose reaching the systemic circulation…
A drug may be metabolized by the liver before it reaches the…
- total body water decreases with maturation resulting from a…
Absorption
factors that affect oral absorption... - pH... - gastric emptying t…
Bioavailability
the percentage of the dose reaching the systemic circulation…
132 terms
Pharmacology
Levodopa
Carbidopa
selegiline/ rasagiline
entacapone/tolcapone
L-Dopa exogenous drug to synthesize dopamine (PD)... - can pass…
Carbidopa inhibits aromatic-L-amino-acid decarboxylase (DOPA…
MaoB inhibtor . MaoB induces inactivation of NA and DA. Thus…
inbition of CoMT -> increase the effectiveness of L-DOPA ther…
Levodopa
L-Dopa exogenous drug to synthesize dopamine (PD)... - can pass…
Carbidopa
Carbidopa inhibits aromatic-L-amino-acid decarboxylase (DOPA…
116 terms
Pharmacology
diffusion rate
Drugs only absorbed when they are
most drugs are
henderson hasselbalch equation
=-DAK(Cout-Cin)/CX... D:diffusion inversely related to size of d…
NONionized and therefore also have a higher lipid solubility
weak electrolytes (can be charged or uncharged)
blood pH is 7.4... gastric pH is 1.4
diffusion rate
=-DAK(Cout-Cin)/CX... D:diffusion inversely related to size of d…
Drugs only absorbed when they are
NONionized and therefore also have a higher lipid solubility
Pharmacology
Abortifacient (Mifeprex; Prostin E2)
Fertility drug (Clomid, Gonal-F)
Hormone replacement therapy (HRT); (Ce…
Oral contraceptive pills (OCP); (Ortho…
Terminates a pregnancy
Triggers ovulation
Replacement estrogen after menopause or loss of ovaries
Prevents conception by blocking ovulation
Abortifacient (Mifeprex; Prostin E2)
Terminates a pregnancy
Fertility drug (Clomid, Gonal-F)
Triggers ovulation
11 terms
Pharmacology
Methadone
Barbituates
Benzodiazepines
-chol
Opioid used in the management of withdrawal states... Long Half-…
drugs that *depress the activity of the central nervous syste…
Sedatives are drugs that are intended to relax and calm. Anti…
Muscarinic agonist
Methadone
Opioid used in the management of withdrawal states... Long Half-…
Barbituates
drugs that *depress the activity of the central nervous syste…
35 terms
Pharmacology
Thiazide diuretics
Loop diuretics
Potassium sparing diuretics
Selective aldosterone blocker
Hydrocholrothiazide
Frusemide
Amiloride
Eplererone
Thiazide diuretics
Hydrocholrothiazide
Loop diuretics
Frusemide
232 terms
Pharmacology
Pharmaceutic Phases
4 stages of Pharmacokinetics
1. Absorption (and factors)
Why do fatty foods increase absorption?
1. Absorption 2. Distribution 3. Metabolism 4. Excretion
Movement of drugs from site of administration into vascular b…
gut motility slows down, more time for med absorption
Pharmaceutic Phases
4 stages of Pharmacokinetics
1. Absorption 2. Distribution 3. Metabolism 4. Excretion
8 terms
Pharmacology
Finasteride/propecia
Tamsulosin
Fioricet (Butalbital/Acetaminophen/Caf…
Meclizine
Tx: BPH. alopecia... Pathway: 5 alpha reductase inhibitor.... class:
tx: BPH, prostates hyperplasia... Pathway: alpha blocker... Class:
tx: Headaches... Pathway: Agoinist for GABA receptors which is a…
tx: vertigo, n/v or dizziness... pathway: antihistamine ... class:…
Finasteride/propecia
Tx: BPH. alopecia... Pathway: 5 alpha reductase inhibitor.... class:
Tamsulosin
tx: BPH, prostates hyperplasia... Pathway: alpha blocker... Class:
22 terms
Pharmacology
Rights...
Pharmacology
CCB
Pharmacodynamics
Patient,Route,time,dosage, documentation, medication, effects…
Study of biological effects of chemicals
Calcium channel blocker-cardiac
Drug effects body
Rights...
Patient,Route,time,dosage, documentation, medication, effects…
Pharmacology
Study of biological effects of chemicals
5 terms
Pharmacology
Agonist
Anatagonist
Passive diffusion
Facilitated diffusion
A drug that binds to a receptor and causes an actio
A drug that binds to a receptor and blocks it or changes it
Molecule that enters the cell freely and naturally going from…
Molecule that enters the cell from area of high concentration…
Agonist
A drug that binds to a receptor and causes an actio
Anatagonist
A drug that binds to a receptor and blocks it or changes it
152 terms
Pharmacology
Enzyme Kinetics
Enzyme Kinetics (cont)
Enzyme Kinetics (cont x2)
Enzyme Kinetics (cont x3)
Enzyme Kinetics
Enzyme Kinetics (cont)
30 terms
Pharmacology
aer/o
alges/o
bronch/o
chem/o
air
sensitivity to pain
bronchial tube
drug
aer/o
air
alges/o
sensitivity to pain
152 terms
Pharmacology
Enzyme Kinetics
Enzyme Kinetics (cont)
Enzyme Kinetics (cont x2)
Enzyme Kinetics (cont x3)
Enzyme Kinetics
Enzyme Kinetics (cont)
141 terms
pharmacology
Alprazolam (Xanax)... CLASS
DIAZEPAM (VALIUM) CLASS
Lorazepam (Ativan) CLASS
Midazolam (Versed) CLASS
ANXIOLYTIC/HYPNOTIC
ANXIOLYTIC/HYPNOTIC
ANXIOLYTIC/HYPNOTIC
ANXIOLYTIC/HYPNOTIC
Alprazolam (Xanax)... CLASS
ANXIOLYTIC/HYPNOTIC
DIAZEPAM (VALIUM) CLASS
ANXIOLYTIC/HYPNOTIC
Pharmacology
Multiplying Fractions
Dividing Fractions
1 Gram is equal to
Medication Calculation formula is D/H…
Step 1: Multiply the two numerators... Step 2: Multiply the two…
Step 1: Flip the second fraction (place denominator on top an…
1000 milligrams
Example: 25mg ordered, 50mg/mL on hand... D= 25mg... H = 50mg... Q= 1…
Multiplying Fractions
Step 1: Multiply the two numerators... Step 2: Multiply the two…
Dividing Fractions
Step 1: Flip the second fraction (place denominator on top an…
82 terms
Pharmacology
ethical drug
generic
inscription
patent medicine
a drug that requires a prescription?
drugs sold without a brandname or trademark?
On a prescription, the name and quantity of a drug?
Drug that can be obtained without a prescription, also called…
ethical drug
a drug that requires a prescription?
generic
drugs sold without a brandname or trademark?
30 terms
Pharmacology
Neurogenic bladder
Priapism
urge incontinence
stress inconrinence
impaired bladder function caused by a nervous system abnormal…
prolonged, painful penile erection
strong, sudden need to void due to the bladder spasm or contr…
losing urine without meaning to during physical activity
Neurogenic bladder
impaired bladder function caused by a nervous system abnormal…
Priapism
prolonged, painful penile erection
49 terms
pharmacology
phase 1
phase 2
phase 3
phase 4
toxicity and determine MTD
response rate and toxicity
efficacy v standard
post-marketing... looking for signals that may not have been pic…
phase 1
toxicity and determine MTD
phase 2
response rate and toxicity
7 terms
pharmacology
Brand name
generic name
DEA
Pharmacodynamics
The name given to a drug when available for commercial use an…
Name assigned to a drug during research and development
Agency that regulates the prescribing and refilling of narcot…
Study of the way drugs act on the body
Brand name
The name given to a drug when available for commercial use an…
generic name
Name assigned to a drug during research and development
37 terms
Pharmacology
pharmacokinetics
pharmacodynamics
pharmacotherapeutics
generic name
what the body does to the drug
what the drug does to the body
the use of drugs in the treatment of disease
most common drug name
pharmacokinetics
what the body does to the drug
pharmacodynamics
what the drug does to the body
110 terms
Pharmacology
Alpha Blocker Adverse Effects
Beta Blocker Use
ED 50
Agonist
Orthostatic hypotension, reflex tachycardia (barorreceptors s…
Agina pectoris, hypertension, cardiac disrhythmias, MI, heart…
Lowest dose needed to produce effect in 50% of population
Binds to receptor and produces effect. Endogenous e.g. NE, Ep…
Alpha Blocker Adverse Effects
Orthostatic hypotension, reflex tachycardia (barorreceptors s…
Beta Blocker Use
Agina pectoris, hypertension, cardiac disrhythmias, MI, heart…
Pharmacology
Antibiotic (Amoxil, Cipro, Rocephin)
Antihistamine (Allegra, Claritan, Bena…
Antitussive (Hycodan, Vicks Formula 44…
Bronchodilator (Proventil, Ventolin, A…
Kills bacteria
Blocks histamine released during allergy attack
Relieves urge to cough
Relaxes bronchospasms, treats asthma
Antibiotic (Amoxil, Cipro, Rocephin)
Kills bacteria
Antihistamine (Allegra, Claritan, Bena…
Blocks histamine released during allergy attack
30 terms
Pharmacology
Allergic reaction
Adverse reaction
anaphylactic shock
angioedema
Immediate hypersensitive reaction by the immune system; it pr…
undesirable drug effect
sudden, server hypersensitivity reaction with symptoms that p…
localized wheals or swelling in the subcutaneous tissue or mu…
Allergic reaction
Immediate hypersensitive reaction by the immune system; it pr…
Adverse reaction
undesirable drug effect
Pharmacology
Etiologic Classifications
Congenital
Degenerative
Iatrogenic
...
born w/ it
break down of body
caused by medical portion
Etiologic Classifications
...
Congenital
born w/ it
58 terms
Pharmacology
Acute care
Administered
Aesthetic
Ambulatory
urgent care setting, such as hospital.
to give medicine orally or by injection.
make pleasing in appearance.
In health care, refers to outpatient care.
Acute care
urgent care setting, such as hospital.
Administered
to give medicine orally or by injection.
447 terms
Pharmacology
Water vs. Fat Soluble
Thiamine (B1)
Cobalamin (B12)
Folate (B9)
Water Soluble = B, C... Fat Soluble = DAKE... Fat soluble vitamins…
Most common deficiency... - alcoholics, elderly (poor nutrition)…
Causes of deficiency:... - pernicious anemia... - ileum resection... -…
Causes of deficiency:... - DHFR inhibitor drugs (methotrexate, s…
Water vs. Fat Soluble
Water Soluble = B, C... Fat Soluble = DAKE... Fat soluble vitamins…
Thiamine (B1)
Most common deficiency... - alcoholics, elderly (poor nutrition)…
166 terms
Pharmacology
STUDY CONSIDERATIONS
Pharmaceutic Phases
Pharmacokinetics
4 Characteristics of Pharmacokinetics
INDICATIONS - why giving certain products?... INTERACTIONS... MONIT…
movement of drugs within the body
1. Absorption... 2. Distribution... 3. Metabolism (AKA biotransform…
STUDY CONSIDERATIONS
INDICATIONS - why giving certain products?... INTERACTIONS... MONIT…
Pharmaceutic Phases
Pharmacology
What is the name under which a drug is…
Which source contains information spec…
What is the most comprehensive referen…
The physician has written an order for…
C. Official
C. United States Pharmacopeia/National Formulary (USP-NF)
B. Drug Interaction Facts
B. Brand and Generic Name section
What is the name under which a drug is…
C. Official
Which source contains information spec…
C. United States Pharmacopeia/National Formulary (USP-NF)
188 terms
Pharmacology
Hypertension
Hypertension Epidemiology
Blood Pressure Range
Hypertension - Etiology
28% American Adults... Asymptomatic until overt end-organ damage…
Smoking... Metabolic syndrome... Obesity... Dyslipidemia... Diabetes... Orga…
Normal <120/80... Prehypertension - 120-135/80-89... Hypertension -…
Only found in 10-15%... Renal artery constriction... Coarctation of…
Hypertension
28% American Adults... Asymptomatic until overt end-organ damage…
Hypertension Epidemiology
Smoking... Metabolic syndrome... Obesity... Dyslipidemia... Diabetes... Orga…
12 terms
Pharmacology
Pharmacology
Drug
Terminology
Sources of drugs
Study of drugs
Any substance going into the body, has an effect on compositi…
Presentation - The form and strength of the drug... Therapeutic…
Naturally occurring... Derived from Animals (hormones)... Synthetic
Pharmacology
Study of drugs
Drug
Any substance going into the body, has an effect on compositi…
Pharmacology
Analgesic
Antipyretic
Anesthetic
Antibiotic
Drug to relieve pain
Drug to reduce fever
Drug which produce insensibility to pain
Drug which is effective against bacterial infections
Analgesic
Drug to relieve pain
Antipyretic
Drug to reduce fever
96 terms
Pharmacology
Pharmacology
Drug
Pharmacokinetics
Inhalation
The study of drugs and their origin, nature, properties, and…
A chemical agent used in the prevention, treatment, or diagno…
The method by which drugs are absorbed, distributed, metaboli…
means of bringing medication or substances to the respiratory…
Pharmacology
The study of drugs and their origin, nature, properties, and…
Drug
A chemical agent used in the prevention, treatment, or diagno…
21 terms
Pharmacology
Therapeutic Response
Side Effects
Adverse Reactions
Idiosyncratic Effects
Desired action of a drug; used to classify medications; deter…
Effects on body system other than the intended target; leads…
Most severe reactions; hypersensitivity reactions; idiosyncra…
Causes and effects that weren't planned or that were unexpected
Therapeutic Response
Desired action of a drug; used to classify medications; deter…
Side Effects
Effects on body system other than the intended target; leads…
13 terms
Pharmacology
Pharmacology
Drug
Terminology
Sources of drugs
Study of drugs
Any substance going into the body, has an effect on compositi…
Presentation - The form and strength of the drug... Therapeutic…
Naturally occurring... Derived from Animals (hormones)... Synthetic
Pharmacology
Study of drugs
Drug
Any substance going into the body, has an effect on compositi…
35 terms
Pharmacology
acetaminophen (Tylenol)
enteric coated aspirin (ECASA)
oxycodone/APAP (Percocet)
morphine sulfate (Duramorph, MS Contin)
Antipyretic/Analgesic/ although a weak inhibitor of the cyclo…
Buffered form of ASA that is easier on stomach in patients ta…
Category: Opiate analgesic/antipyretic, Use: Moderate to seve…
Opioid used to treat severe pain. Sometimes used as an anesth…
acetaminophen (Tylenol)
Antipyretic/Analgesic/ although a weak inhibitor of the cyclo…
enteric coated aspirin (ECASA)
Buffered form of ASA that is easier on stomach in patients ta…
13 terms
pharmacology
Epinephrine
Benadryl
Afrin nasal spray
Flonase
Epinephrine
Benadryl
73 terms
Pharmacology
Alpha1 stimulation
Alpha2 stimulation
Beta1 stimulation
Beta2 stimulation
-Increases cardiac contractility, vasoconstriction.... -Dilates…
-Inhibits norepenephrine release... -Promotes vasodilation and d…
-increases cardiac contractility, Heart rate... -Increases renin…
-Promotes GI relaxation... -Bronchodilation... -Increases blood flo…
Alpha1 stimulation
-Increases cardiac contractility, vasoconstriction.... -Dilates…
Alpha2 stimulation
-Inhibits norepenephrine release... -Promotes vasodilation and d…
98 terms
Pharmacology
Respiratory stimulants (analeptics)
Amphetamines (anorexiant)
Analgesic Agonist (opioids)
Narcotic Antagonist
PROTOTYPE: Doxapram (dopram) USES: stimulate breathing ACTION…
PROTOTYPE: Dexedrine (dextramphetamine) USE: to treat narcole…
PROTOTYPE: Morphine Sulfate ACTION: binds to opiate receptor…
PROTOTYPE: Narcan (naloxone hydrochloride) USE: after surgery…
Respiratory stimulants (analeptics)
PROTOTYPE: Doxapram (dopram) USES: stimulate breathing ACTION…
Amphetamines (anorexiant)
PROTOTYPE: Dexedrine (dextramphetamine) USE: to treat narcole…
592 terms
Pharmacology
Name the two terms associated with the…
____ of the drug is plotted where the…
____ of a drug may exhibit is plotted…
the amount of a drug to produce an eff…
therapeutic range... maximum response
thraputic range
maximum response
potency
Name the two terms associated with the…
therapeutic range... maximum response
____ of the drug is plotted where the…
thraputic range
pharmacology
pharmacology
molecular pharmacology
pharmacodynamics
pharmacogenetics
study of drugs and interactions with living organisms
study of chemical structures of drugs and the effects of drug…
mechanisms of action by which drugs produce their effects bas…
how the genetic makeup of different people affects their resp…
pharmacology
study of drugs and interactions with living organisms
molecular pharmacology
study of chemical structures of drugs and the effects of drug…
23 terms
Pharmacology
Abilify
Accupril
Aciphex
Aciphex
Abilify
Accupril
88 terms
Pharmacology
What are the classes of neuromuscular…
What drugs, clinical situations, or co…
Which neuromuscular blockers have card…
What drugs will exacerbate neuromuscul…
1. Depolarizing drugs - i.e succinylcholine. Ach-Ach compound…
Has a high breakdown in the plasma after injection by pseudoc…
Succinylcholine can also bind muscarinic Ach R on heart --> i…
Polymixins --> decrease post synaptic sensitivity to Ach and…
What are the classes of neuromuscular…
1. Depolarizing drugs - i.e succinylcholine. Ach-Ach compound…
What drugs, clinical situations, or co…
Has a high breakdown in the plasma after injection by pseudoc…
124 terms
Pharmacology
Drug
Side Effects
Affinity
Efficacy
Chemical that affects physiological function in a specific way
Not high enough specificity i.e. drug binds to other receptor…
Ability of a drug to bind to a receptor
Ability of drug to activate a receptor
Drug
Chemical that affects physiological function in a specific way
Side Effects
Not high enough specificity i.e. drug binds to other receptor…
152 terms
Pharmacology
Enzyme Kinetics
Enzyme Kinetics (cont)
Enzyme Kinetics (cont x2)
Enzyme Kinetics (cont x3)
Enzyme Kinetics
Enzyme Kinetics (cont)
31 terms
Pharmacology
Therapuetic Effect
Side Effect
Adverse Effect
Drug Toxicity
Desired effect, is the primary effect intended, that is, the…
Secondary effect, is one that is unintended. Usually they are…
More severe side effect. May justify discontinuation of a drug.
Harmful effects of a drug on an organism. Results from overdo…
Therapuetic Effect
Desired effect, is the primary effect intended, that is, the…
Side Effect
Secondary effect, is one that is unintended. Usually they are…
Pharmacology
Pharmacology
Pharmac/o
-ology
Oral
the study of the nature, uses, and effects of drugs in medica…
drug
study of
Taken through the mouth and absorbed in the digestive tract.
Pharmacology
the study of the nature, uses, and effects of drugs in medica…
Pharmac/o
drug
32 terms
Pharmacology
affinity
efficacy
excitation
inhibition
a drug's attraction to a receptor
a drug's ability to activate a receptor; also known as the mo…
a way a drug activates an excitatory system or blocking an in…
a way a drug activates an inhibitory system or by blocking an…
affinity
a drug's attraction to a receptor
efficacy
a drug's ability to activate a receptor; also known as the mo…
62 terms
Pharmacology
Gram + only
Gram -ve only
Extended spectrum
+ve, -ve, extended
Penicillin V / Anti-staph /G... Bacitracin... Cephalosporins (1st g…
Anti-Pseudomonal penicillin... Aztreoman... Cephalosporin (2nd gene…
Amoxicillin/Ampicillin... Carbapenems ... Cepholosporins (3+4) ... Chl…
Aminoglycosides ... Clindamycin
Gram + only
Penicillin V / Anti-staph /G... Bacitracin... Cephalosporins (1st g…
Gram -ve only
Anti-Pseudomonal penicillin... Aztreoman... Cephalosporin (2nd gene…
Pharmacology
Drugs
Roles of DH
FDA
Regulates the labeling and advertising…
chemical substances used for the diagnosis, prevention, or Tx…
1. Obtaining HH 2. Administering drugs in office. 3. Handling…
quality controlin manufacturing plants anddecides what drugs…
FDA
Drugs
chemical substances used for the diagnosis, prevention, or Tx…
Roles of DH
1. Obtaining HH 2. Administering drugs in office. 3. Handling…
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