pharmacology
SETS
Pharmacology | USMLE Step 1/COMLEX Level 1 Guide
amedschoolkidPLUS
CCS drugs (cell-cycle specific)
CCNS drugs (cell-cycle non-specific)
_____ drugs are used for recruitment an…
Adverse effects of CCS drugs
Anticancer drugs that are:... --> Phase-specific ... --> Higher sele…
--> Anticancer drugs that can sterilize tumor cells regardless…
CCNS --> Causes increased vulnerability to CCS agents afterwar…
The most rapidly proliferating normal cells are likely to suff…
CCS drugs (cell-cycle specific)
Anticancer drugs that are:... --> Phase-specific ... --> Higher sele…
CCNS drugs (cell-cycle non-specific)
--> Anticancer drugs that can sterilize tumor cells regardless…
STUDY CONSIDERATIONS
Pharmacokinetics
4 Characteristics of Pharmacokinetics
1. Absorption
INDICATIONS - why giving certain products?... NURSING ACTIONS... PAT…
movement of drugs within the body
1. Absorption... 2. Distribution... 3. Metabolism (AKA biotransforma…
Movement of drugs from their site of administration into the v…
STUDY CONSIDERATIONS
INDICATIONS - why giving certain products?... NURSING ACTIONS... PAT…
Pharmacokinetics
movement of drugs within the body
Pharmacology
what is a drug
Drug Nomenclature
Drug Resources
the study of drugs... -Toxicology (study of environmental toxins)…
any chemical that changes the processes of living
Chemical name: N-Acetyl-p-aminophenol (development stage) ... Ge…
1. physicians desk reference (PDR)... 2. Nursing drug guides (mos…
Pharmacology
the study of drugs... -Toxicology (study of environmental toxins)…
what is a drug
any chemical that changes the processes of living
What are the major functions of the α1…
What are the major functions of the α2…
What are the major functions of the β1…
What are the major functions of the β2…
Increase vascular smooth muscle contraction, increase pupillar…
Decrease sympathetic outflow, decrease insulin release, decrea…
Increase heart rate, increase contractility, increase renin re…
Vasodilation, bronchodilation, increase lipolysis, increase in…
What are the major functions of the α1…
Increase vascular smooth muscle contraction, increase pupillar…
What are the major functions of the α2…
Decrease sympathetic outflow, decrease insulin release, decrea…
An experienced nurse has completed a ph…
Any pill with _____ in its name is a…
The nurse is caring for a client with p…
Before prescribing, the health care pr…
"Liquid medications have a slower onset than capsules."
SR, LA, XL, or XR
Gender
- How the drug is given; the health care provider must determ…
An experienced nurse has completed a ph…
"Liquid medications have a slower onset than capsules."
Any pill with _____ in its name is a…
SR, LA, XL, or XR
What are the major functions of the α1…
What are the major functions of the α2…
What are the major functions of the β1…
What are the major functions of the β2…
Increase vascular smooth muscle contraction, increase pupillar…
Decrease sympathetic outflow, decrease insulin release, decrea…
Increase heart rate, increase contractility, increase renin re…
Vasodilation, bronchodilation, increase lipolysis, increase in…
What are the major functions of the α1…
Increase vascular smooth muscle contraction, increase pupillar…
What are the major functions of the α2…
Decrease sympathetic outflow, decrease insulin release, decrea…
What are the major functions of the α1…
What are the major functions of the α2…
What are the major functions of the β1…
What are the major functions of the β2…
Increase vascular smooth muscle contraction, increase pupillar…
Decrease sympathetic outflow, decrease insulin release, decrea…
Increase heart rate, increase contractility, increase renin re…
Vasodilation, bronchodilation, increase lipolysis, increase in…
What are the major functions of the α1…
Increase vascular smooth muscle contraction, increase pupillar…
What are the major functions of the α2…
Decrease sympathetic outflow, decrease insulin release, decrea…
2
2
1
1
Which nursing action is the priority when administering chelat…
A 67-year-old client has tested positive for influenza A. The…
Which first line medication would the nurse state is used to t…
A mother complains that her child's teeth have become yellow i…
2
Which nursing action is the priority when administering chelat…
2
A 67-year-old client has tested positive for influenza A. The…
Agonist
Antagonist
MDI
DPI
produce an action ... i.e. when the muscles relax... morphine is an…
oppose/reduce an action... i.e. work against the muscles... competit…
shake device 5/6 times... take deep breath 3-5 seconds before inh…
dry powder inhalation... do not shake device
Agonist
produce an action ... i.e. when the muscles relax... morphine is an…
Antagonist
oppose/reduce an action... i.e. work against the muscles... competit…
jrachicTEACHER
Pharmacology
Drug/Medicine
Who controls meds in the US?
What is the purpose of the FDA?
Study of drugs and how they affect the body
Any substance that produces a physical or chemical change in t…
FDA, DEA
Sets standards for the purity, strength, and composition of al…
Pharmacology
Study of drugs and how they affect the body
Drug/Medicine
Any substance that produces a physical or chemical change in t…
During the implementation phase of the…
The nurse would recognize which of thes…
The nurse is reviewing a prescription f…
How would the nurse best describe the h…
b. Following the five rights of medication administration
c. right drug, right time, right patient, right dose, right ro…
a. The prescriber signature
a. It is the time it takes for one half of the original availa…
During the implementation phase of the…
b. Following the five rights of medication administration
The nurse would recognize which of thes…
c. right drug, right time, right patient, right dose, right ro…
Pharmacology
Herbal Medicine
drugs have several names assigned to th…
Chemical Name (scienticfic name)
Study of drugs and their action on living organisms
herbal medicine, herbalism, and herbal therapy are names for c…
chemical name,a generic name (nonproprietary), the official na…
Gives the exact chemical makeup of the drug and placing of the…
Pharmacology
Study of drugs and their action on living organisms
Herbal Medicine
herbal medicine, herbalism, and herbal therapy are names for c…
Aminoglycosides Class
Sulfonamides, Tetracyclines, Fluoroquin…
ceftriaxone (Rocephin)
Clavulanic, Tazobactam, Sulbactam
Name an antibiotic class that you would worry about nephrotoxi…
Name 3 antibiotic classes that have an the adverse effect, pho…
Which antibiotic can pass the blood brain barrier and get into…
Name the 3 chemicals used with penicillins as a beta-lactamase…
Aminoglycosides Class
Name an antibiotic class that you would worry about nephrotoxi…
Sulfonamides, Tetracyclines, Fluoroquin…
Name 3 antibiotic classes that have an the adverse effect, pho…
anticholinergic
beta blocker
calcium channel blocker
corticosteroid
-kind:atropine... -for heart block/ bradycardia->*result in in…
-decrease HR, BP, contractility, stroke volume->**HR : low a…
-inhibit the influx of calcium ions to myocardial and vascular…
*prolonged use... -*inhibit inflammatory process* including cap…
anticholinergic
-kind:atropine... -for heart block/ bradycardia->*result in in…
beta blocker
-decrease HR, BP, contractility, stroke volume->**HR : low a…
ratios
proportion
formula
dimensional analysis
comparisons between two things
statement saying those two ratios are equal
rule prescribing how to calculate a dosage
method based on the premise that any number can be multiplied…
ratios
comparisons between two things
proportion
statement saying those two ratios are equal
Activated Charcoal
Adenosine (Adenocard)
Albuterol (Proventil)
Amiodarone (Cordarone)
CLASS: adsorbent... ACTIONS: adsorbs toxins by chemical binding a…
CLASS: antidysrhythmic... ACTIONS: slows atrioventricular conduct…
CLASS: sympathomimetic (Beta 2 selective)... ACTIONS: bronchodila…
CLASS: antidysrhythmic... ACTIONS: prolongs action potential and…
Activated Charcoal
CLASS: adsorbent... ACTIONS: adsorbs toxins by chemical binding a…
Adenosine (Adenocard)
CLASS: antidysrhythmic... ACTIONS: slows atrioventricular conduct…
erika_moon4TEACHER
Antihypertensives
Betablockers
What additional effects of betablockers…
In what population should betablockers…
These drugs affect both the blood pressure and the rhythm of t…
Usually end in -olol.... Propranolol (Inderal)... Atenolol (Tenor…
The nurse should monitor for broncho constriction and bronchos…
Betablockers should be used cautiously in patients who suffer…
Antihypertensives
These drugs affect both the blood pressure and the rhythm of t…
Betablockers
Usually end in -olol.... Propranolol (Inderal)... Atenolol (Tenor…
CHAPTER
a. "Do not take this medication during…
b. Avoid taking aspirin concurrently.…
a. Uloric reduces the synthesis of uric…
24
What is the most important information for the nurse to includ…
The nurse providing patient education to the patient starting…
Which statement best describes the method of actions of Uloric…
CHAPTER
24
a. "Do not take this medication during…
What is the most important information for the nurse to includ…
Selective Cox-2 inhibitors
Neuroleptic malignant Syndrome
Modafinil
Tetracyclines
eg. celecoxib. ... Cox-2 is an inducible enzyme that is unregula…
adverse reaction to antipsychotic medication characterized by…
first line treatment for narcolepsy. ... Amphetamines are second…
are teratogenic and can cause fetal bone growth retardation as…
Selective Cox-2 inhibitors
eg. celecoxib. ... Cox-2 is an inducible enzyme that is unregula…
Neuroleptic malignant Syndrome
adverse reaction to antipsychotic medication characterized by…
Therapeutic Drug Levels: Aminophylline
Therapeutic Drug Levels: Carbamazepine
Therapeutic Drug Levels: Digoxin
Therapeutic Drug Levels: Gentamicin
10 to 20 mcg/ml... Toxic Level: greater than 20 mcg/ml
5 to 12 mcg/ml
0.8 to 2.0 ng/ml... Toxic Level: greater than 3.4 ng/ml
0.5 to 0.8 ng/ml
Therapeutic Drug Levels: Aminophylline
10 to 20 mcg/ml... Toxic Level: greater than 20 mcg/ml
Therapeutic Drug Levels: Carbamazepine
5 to 12 mcg/ml
Pharmacokinetic factors that affect pre…
The point in time on the drug concentra…
An NP would prescribe the liquid from o…
The NP chooses to give cephalexin every…
Bioavailabilty
Onset of action
A 6-year-old child may have problems swallowing a pill
Biological half-life
Pharmacokinetic factors that affect pre…
Bioavailabilty
The point in time on the drug concentra…
Onset of action
Explain Pharmacokinetics
Pharmacodynamics
Summarize the main drug actions
Desired activity is achieved through wh…
The study of how drugs are moved through the body and are enco…
study of the biochemical and physiologic effects of drugs on t…
1 - stimulating action through direct receptor agonism and dow…
-Cellular membrane disruption... -Chemical reaction with downstre…
Explain Pharmacokinetics
The study of how drugs are moved through the body and are enco…
Pharmacodynamics
study of the biochemical and physiologic effects of drugs on t…
A patient is to receive rifampin. Which…
Which of the following is considered a…
When administering a secondary drug to…
The nurse explains to the client that p…
"Your urine or sweat may become orange in color."
Ciprofloxacin
extrapulmonary TB
Those who have been in close contact with a person with tuberc…
A patient is to receive rifampin. Which…
"Your urine or sweat may become orange in color."
Which of the following is considered a…
Ciprofloxacin
Amiodarone (Cordarone)
Adenosine (Adenocard)
Atropine
Aspirin (ASA)
Class: Antiarrhythmic... Indications: VF/VT and VT with a pulse…
Class: Antiarrhythmic... ... Indications: Symptomatic SVT... - Initia…
Class: Anticholinergic... Indications: Symptomatic Bradycardia…
Class: NSAID, platelet aggregate ... Indications: STEMI, Chest P…
Amiodarone (Cordarone)
Class: Antiarrhythmic... Indications: VF/VT and VT with a pulse…
Adenosine (Adenocard)
Class: Antiarrhythmic... ... Indications: Symptomatic SVT... - Initia…
Central Nervous System Agents... *********…
Which class of drugs is considered the…
What is the main neurotransmitter invol…
How do the serotonin reuptake inhibitor…
Central Nervous System Agents... ********************************…
The serotonin reuptake inhibitors (SSRIs) are the drugs of cho…
Serotonin is the main neurotransmitter involved in the etiolog…
These drugs block the reuptake of serotonin at the neural endi…
Central Nervous System Agents... *********…
Central Nervous System Agents... ********************************…
Which class of drugs is considered the…
The serotonin reuptake inhibitors (SSRIs) are the drugs of cho…