Study sets matching "pharmacology"

Study sets
Classes
Users

Study sets matching "pharmacology"

152 terms
Pharmacology
Enzyme Kinetics
Enzyme Kinetics (cont)
Enzyme Kinetics (cont x2)
Enzyme Kinetics (cont x3)
Enzyme Kinetics
Enzyme Kinetics (cont)
33 terms
Pharmacology
Amantadine
Ribavirin
Oseltamivir
Pralidoxime
Prevents viral assembly, inhibits viral release with interact…
Inhibits viral RNA polymerase activity and RNA fragment initi…
Inhibitor of neuraminidases of influenza A and B viruses; pre…
Antidote to organophosphorus anticholinergics; it reactivates…
Amantadine
Prevents viral assembly, inhibits viral release with interact…
Ribavirin
Inhibits viral RNA polymerase activity and RNA fragment initi…
41 terms
Pharmacology
anticholinergic
beta blocker
calcium channel blocker
corticosteroid
-kind:atropine... -for heart block/ bradycardia->*result in i…
-decrease HR, BP, contractility, stroke volume->**HR : low…
-inhibit the influx of calcium ions to myocardial and vascula…
*prolonged use... -*inhibit inflammatory process* including ca…
anticholinergic
-kind:atropine... -for heart block/ bradycardia->*result in i…
beta blocker
-decrease HR, BP, contractility, stroke volume->**HR : low…
pharmacology
antineoplastic
advent
noxious
insulin
against tumour
arrival, coming
distructive
antineoplastic
against tumour
advent
arrival, coming
97 terms
Pharmacology
Mixed Function Oxidases require ______…
Where does oxidation (phase 1) take pl…
P450 enzyme responsible for over 50% o…
accelerated metabolism and a decrease…
NADPH and molecular oxygen
Smooth ER
CYP3A4
Induction
Mixed Function Oxidases require ______…
NADPH and molecular oxygen
Where does oxidation (phase 1) take pl…
Smooth ER
202 terms
Pharmacology
compliance
medication error
Noncompliance
Nursing process
Implementation of fulfillment of a prescriber's or caregiver'…
Any preventable adverse drug event involving inappropriate me…
an informed decision on the part of the patient not to adhere…
an organizational framework for the practice of nursing. It e…
compliance
Implementation of fulfillment of a prescriber's or caregiver'…
medication error
Any preventable adverse drug event involving inappropriate me…
20 terms
Pharmacology
Bioavailability
Rate of elimination
Half life
Clearance
OR clearance * concentration
Bioavailability
Rate of elimination
OR clearance * concentration
506 terms
Pharmacology
Selective Cox-2 inhibitors
Neuroleptic malignant Syndrome
Modafinil
Tetracyclines
eg. celecoxib. ... Cox-2 is an inducible enzyme that is unregul…
adverse reaction to antipsychotic medication characterized by…
first line treatment for narcolepsy. ... Amphetamines are secon…
are teratogenic and can cause fetal bone growth retardation a…
Selective Cox-2 inhibitors
eg. celecoxib. ... Cox-2 is an inducible enzyme that is unregul…
Neuroleptic malignant Syndrome
adverse reaction to antipsychotic medication characterized by…
53 terms
Pharmacology
ALEMTUZUMAB... Use... MoA
ANTITHYMOCYTE GLOBULIN RABBIT ... Use... MoA
Adverse effects of lymphoid depleting…
BASILIXIMAB ... Use... MoA
INDUCTION: Lymphocyte depleting... Monoclonal; Binds CD52 on l…
INDUCTION: Lymphocyte depleting... Polyclonal; Binds T cell su…
N/V/D... HA... Myelosuppresion
INDUCTION: NON-Lymphocyte depleting... IL-2 receptor antagonist
ALEMTUZUMAB... Use... MoA
INDUCTION: Lymphocyte depleting... Monoclonal; Binds CD52 on l…
ANTITHYMOCYTE GLOBULIN RABBIT ... Use... MoA
INDUCTION: Lymphocyte depleting... Polyclonal; Binds T cell su…
213 terms
Pharmacology
________ is a A science that draws on…
define Drug
define Pharmacology
Clinical pharmacology
Pharmacology
Any chemical that can affect living processes
Study of drugs and their interactions with living systems
Study of drugs in humans
________ is a A science that draws on…
Pharmacology
define Drug
Any chemical that can affect living processes
129 terms
Pharmacology
Pharmacology
what is a drug
Drug Nomenclature
Drug Resources
the study of drugs... -Toxicology (study of environmental toxins…
any chemical that changes the processes of living
Chemical name: N-Acetyl-p-aminophenol (development stage) ... G…
1. physicians desk reference (PDR)... 2. Nursing drug guides (mo…
Pharmacology
the study of drugs... -Toxicology (study of environmental toxins…
what is a drug
any chemical that changes the processes of living
15 terms
Pharmacology
SL
Bucc/o
intra-
Pharmacology
Abbreviation for sublingual - below the tongue
Combining form for cheek (between cheek and gum)
prefix meaning WITHIN... ID = intradermal (within skin), IM = in…
study of chemical/drug substances... Pharmac/o root for drug, lo…
SL
Abbreviation for sublingual - below the tongue
Bucc/o
Combining form for cheek (between cheek and gum)
2,000 terms
Pharmacology
How are estrogens for oral contracepti…
Central Nervous System Agents... ********…
Which class of drugs is considered the…
What is the main neurotransmitter invo…
They are typically packaged as a 28 day dose pack.
Central Nervous System Agents... *******************************…
The serotonin reuptake inhibitors (SSRIs) are the drugs of ch…
Serotonin is the main neurotransmitter involved in the etiolo…
How are estrogens for oral contracepti…
They are typically packaged as a 28 day dose pack.
Central Nervous System Agents... ********…
Central Nervous System Agents... *******************************…
55 terms
Pharmacology
What is the drug Etomidate used for?
Is the drug Benzodiazepines used for A…
What is the drug Flumazenil used for?
Is Ketamine used in Airway Management?
Airway Management... Sedative that begins working in 30 to 60 se…
Airway Management... Class of drug having anti-seizure, anxiolyt…
Airway Management... Competitive benzodiazepine antagonist. Will…
Airway Management... Causes produced dissociation & general anes…
What is the drug Etomidate used for?
Airway Management... Sedative that begins working in 30 to 60 se…
Is the drug Benzodiazepines used for A…
Airway Management... Class of drug having anti-seizure, anxiolyt…
63 terms
Pharmacology
The 5 sources of drugs
Definition of "Pharmaco-"
CVM
FDA
Plants, Minerals, Animals, Synthetics, and Molds/Bacteria
Drug, medicine
Center for Veterinary Medicine
Food and Drug Adminstration
The 5 sources of drugs
Plants, Minerals, Animals, Synthetics, and Molds/Bacteria
Definition of "Pharmaco-"
Drug, medicine
202 terms
Pharmacology
compliance
medication error
Noncompliance
Nursing process
Implementation of fulfillment of a prescriber's or caregiver'…
Any preventable adverse drug event involving inappropriate me…
an informed decision on the part of the patient not to adhere…
an organizational framework for the practice of nursing. It e…
compliance
Implementation of fulfillment of a prescriber's or caregiver'…
medication error
Any preventable adverse drug event involving inappropriate me…
Pharmacology
Prescription Drugs
Controlled Substance
Pharmaceutic phase
Pharmacokinetic phase
Must be prescribed by a licensed person, MD, PA, NP
Most carefully monitored, most likely to be counted medicatio…
dissolution of solid ... disintegration of oral med
absorption, distribution, metabolism- onset, peak, duration,…
Prescription Drugs
Must be prescribed by a licensed person, MD, PA, NP
Controlled Substance
Most carefully monitored, most likely to be counted medicatio…
93 terms
Pharmacology
Methylprednisolone: Trade Name
Methylprednisolone: Class
Methylprednisolone: Mechanism
Methylprednisolone: Indications
Solu-Medrol
Corticosteroid ... (Adrenal; Synthetic)
Reduces inflammation by multiple mechanisms
Anaphylaxis. Asthma. COPD.
Methylprednisolone: Trade Name
Solu-Medrol
Methylprednisolone: Class
Corticosteroid ... (Adrenal; Synthetic)
Pharmacology
Enzyme Kinetics
Enzyme Kinetics (cont)
Enzyme Kinetics (cont x2)
Enzyme Kinetics (cont x3)
Enzyme Kinetics
Enzyme Kinetics (cont)
72 terms
pharmacology
188 billion
24 billion
12 billion
complementary alternative medicines
what amount of money is spent each year on presciption drugs…
what amount of money is spent each year on non-presciption dr…
what amount of money is spent each year on herbals and dietar…
herbals and dietary supplements are labeled CAM, what does CA…
188 billion
what amount of money is spent each year on presciption drugs…
24 billion
what amount of money is spent each year on non-presciption dr…
10 terms
Pharmacology
methotrexate
TNF-Alpha inhibitor
Inhaled steroids won't have Cushing sy…
aspirin allergy might cause asthma, wh…
Inhibits FH2---FH4, anti tumor, immune suppression
PrePosed to TB
...
...
methotrexate
Inhibits FH2---FH4, anti tumor, immune suppression
TNF-Alpha inhibitor
PrePosed to TB
869 terms
Pharmacology
What are the major functions of the α1…
What are the major functions of the α2…
What are the major functions of the β1…
What are the major functions of the β2…
Increase vascular smooth muscle contraction, increase pupilla…
Decrease sympathetic outflow, decrease insulin release, decre…
Increase heart rate, increase contractility, increase renin r…
Vasodilation, bronchodilation, increase lipolysis, increase i…
What are the major functions of the α1…
Increase vascular smooth muscle contraction, increase pupilla…
What are the major functions of the α2…
Decrease sympathetic outflow, decrease insulin release, decre…
233 terms
Pharmacology
Anti-seizure medications that primaril…
Anti-seizure medications that target b…
Anti-seizure medications that target p…
Blockade of T-type Calcium channels is…
Carbamazepine... Phenytoin... Primidone... Valproic Acid
Barbituates... Benzodiazepines (primarily GABA)
Ethosuximide
Generalized Absence Seizures
Anti-seizure medications that primaril…
Carbamazepine... Phenytoin... Primidone... Valproic Acid
Anti-seizure medications that target b…
Barbituates... Benzodiazepines (primarily GABA)
337 terms
Pharmacology
CYP phenotyping probes
metyrosine
CNS acetylchoilne
methyldopa
caffeine CYP1A2... dextromethorphan CYP2D6... midazolam CYP3A4... omep…
inhibits tyrosine hydroxylase... large reduction of all catechol…
recurrent motor collaterals in SC... septo-hippocampal projectio…
methyldopa → methylnorepinephrine... false transmitter... affinity…
CYP phenotyping probes
caffeine CYP1A2... dextromethorphan CYP2D6... midazolam CYP3A4... omep…
metyrosine
inhibits tyrosine hydroxylase... large reduction of all catechol…
869 terms
Pharmacology
What are the major functions of the α1…
What are the major functions of the α2…
What are the major functions of the β1…
What are the major functions of the β2…
Increase vascular smooth muscle contraction, increase pupilla…
Decrease sympathetic outflow, decrease insulin release, decre…
Increase heart rate, increase contractility, increase renin r…
Vasodilation, bronchodilation, increase lipolysis, increase i…
What are the major functions of the α1…
Increase vascular smooth muscle contraction, increase pupilla…
What are the major functions of the α2…
Decrease sympathetic outflow, decrease insulin release, decre…
202 terms
Pharmacology
compliance
medication error
Noncompliance
Nursing process
Implementation of fulfillment of a prescriber's or caregiver'…
Any preventable adverse drug event involving inappropriate me…
an informed decision on the part of the patient not to adhere…
an organizational framework for the practice of nursing. It e…
compliance
Implementation of fulfillment of a prescriber's or caregiver'…
medication error
Any preventable adverse drug event involving inappropriate me…
45 terms
Pharmacology
Drug clearance
Primary organs of drug metabolism and…
Renal clearance
Hepatic clearance
A measure of drug elimination.
Liver and Kidney
Occurs via filtration through the glomerulus and active secre…
The liver is the primary site of drug metabolism.
Drug clearance
A measure of drug elimination.
Primary organs of drug metabolism and…
Liver and Kidney
67 terms
Pharmacology
FOR ALL:
Anti-Arrhythmics 1b
Anti-Arrhythmics 1a
Anti-Arrhythmics 1c
EXAMPLE... MOA ... INDICATIONS... CONTRAINDICATIONS... SIDE FX
C/I Digoxin
C/I Digoxin ... - for WPW, last resort = ... Destruction of the abn…
FOR ALL:
EXAMPLE... MOA ... INDICATIONS... CONTRAINDICATIONS... SIDE FX
Anti-Arrhythmics 1b
Pharmacology
-conazoles
-mab
cef- (ceph-)
-pril
antifungal
monoclonal antibody
cephalosporin antibiotics
angiotensin converting enzyme (ACE) inhibitors
-conazoles
antifungal
-mab
monoclonal antibody
PHARMACOLOGY
ANS
Hemicholinium
Metyrosine
Vesamicol
ANS
- Affects Ach transmission... - Inhibits synthesis of neurotrans…
- Affects sympathetic transmission... - Inhibits synthesis of ne…
- Affects Ach transmission... - Prevent vesicular storage of neu…
ANS
ANS
Hemicholinium
- Affects Ach transmission... - Inhibits synthesis of neurotrans…
5 terms
Pharmacology
Pharmacology
Pharmacokinetics
Pharmacodynamics
HIPPA
study of drugs, uses and interactions in living systems
how drugs move through the body
how the body processes the drugs
Health Insurance Portability and Accountability Act
Pharmacology
study of drugs, uses and interactions in living systems
Pharmacokinetics
how drugs move through the body
pharmacology
Analgesics
Anesthetic agents
Anti-infectives
antivirals
-drugs that alleviate pain without causing anesthesia... -two gr…
-cause an absence of sensation or pain... -two groups: local and…
treat disease produced by microorganisms such as bacteria, vi…
prevent the replication of viruses
Analgesics
-drugs that alleviate pain without causing anesthesia... -two gr…
Anesthetic agents
-cause an absence of sensation or pain... -two groups: local and…
461 terms
Pharmacology
therapeutic effect
drug interactions
side effects
adverse drug reactions (ADRs)
the desired or intended effect of a particular medication
interactions between different drugs
any minor effect of a drug on body cells or tissues that is n…
an undesirable drug effect that ranges from mild untoward eff…
therapeutic effect
the desired or intended effect of a particular medication
drug interactions
interactions between different drugs
41 terms
Pharmacology
anticholinergic
beta blocker
calcium channel blocker
corticosteroid
-kind:atropine... -for heart block/ bradycardia->*result in i…
-decrease HR, BP, contractility, stroke volume->**HR : low…
-inhibit the influx of calcium ions to myocardial and vascula…
*prolonged use... -*inhibit inflammatory process* including ca…
anticholinergic
-kind:atropine... -for heart block/ bradycardia->*result in i…
beta blocker
-decrease HR, BP, contractility, stroke volume->**HR : low…
6 terms
Pharmacology
Quinidine (class 1A)
Procainamide, Dysopiramide
Class 1B
Class 1B drugs
1- M receptors blockade (increase HR and AV conduction)... 2- a-…
1-Less M receptor block... 2-Metabolized via N-acetyltransferase…
1- Block fast Na channels (preferentially inactivated channel…
Lidocaine, mexiletine (CNS toxicity, seizures)
Quinidine (class 1A)
1- M receptors blockade (increase HR and AV conduction)... 2- a-…
Procainamide, Dysopiramide
1-Less M receptor block... 2-Metabolized via N-acetyltransferase…
55 terms
Pharmacology
Naltrexone
Naloxone
Buprenorphine
Gabapentin Side Effects
Opioid antagonist... Should be stopped 4 half-lives before surge…
Opioid antagonist... No oral bioavailability... SE: increased HR an…
Partial mu opioid agonist and kappa antagonist... Ceiling effect…
Edema, cognitive, weight gain
Naltrexone
Opioid antagonist... Should be stopped 4 half-lives before surge…
Naloxone
Opioid antagonist... No oral bioavailability... SE: increased HR an…
163 terms
Pharmacology
pharmacokinetics definition
pharmacodynamics definition
agonist
antagonist
study of how drug moves into, through, and out of body
study of how drug produces its effects in body
drug molecule has an effect on the cell "intrinsic activity"
combines with drug molecule and produces opposite affect of 1…
pharmacokinetics definition
study of how drug moves into, through, and out of body
pharmacodynamics definition
study of how drug produces its effects in body
11 terms
Pharmacology
pharmacokinetics
pharmacodynamics
agonist
A
what body dose to drug? (absorption, distribution, elimination)
drug does the body
drugs that favors the active conformation of receptor
which drug is more potent?
pharmacokinetics
what body dose to drug? (absorption, distribution, elimination)
pharmacodynamics
drug does the body
68 terms
Pharmacology
Inotropic effect?... Example?
Chronotropic effect?... Example?
Dromotropic effect... Example?
Treatment of heart muscle failure?
Force or energy of muscular contractions... Positive Inotropic d…
Rate of the heartbeat... Negative chronotropic drug
Conduction of electrical impulses... Negative dromotropic drug
Positive Inotropic Drug
Inotropic effect?... Example?
Force or energy of muscular contractions... Positive Inotropic d…
Chronotropic effect?... Example?
Rate of the heartbeat... Negative chronotropic drug
60 terms
Pharmacology
alges/o
chem/o
cutane/o or derm/o
esthes/o
Sensitivity to pain
Drug
Skin
Feeling
alges/o
Sensitivity to pain
chem/o
Drug
88 terms
PHARMACOLOGY
Medications
pharmaceutics
pharmacokinetics
absorption
a substance administered for the diagnosis, cure, treatment,…
The science of dosage form design... example is tablets, capsule…
Study of how various dosage forms influence pharmokinetic and…
rate at which a drug leaves its site of administration and is…
Medications
a substance administered for the diagnosis, cure, treatment,…
pharmaceutics
The science of dosage form design... example is tablets, capsule…
506 terms
Pharmacology
Selective Cox-2 inhibitors
Neuroleptic malignant Syndrome
Modafinil
Tetracyclines
eg. celecoxib. ... Cox-2 is an inducible enzyme that is unregul…
adverse reaction to antipsychotic medication characterized by…
first line treatment for narcolepsy. ... Amphetamines are secon…
are teratogenic and can cause fetal bone growth retardation a…
Selective Cox-2 inhibitors
eg. celecoxib. ... Cox-2 is an inducible enzyme that is unregul…
Neuroleptic malignant Syndrome
adverse reaction to antipsychotic medication characterized by…
86 terms
Pharmacology
Circulating adrenaline from the adrena…
NANC innervation is
Inhibitory NO (NANC) acts on bronchial…
Excitatory substance P and neurokinin…
B2 receptors - results in an increase of cAMP causing smooth…
nonadrenergic noncholinergic - these include a variety of pep…
This causes smooth muscle relaxation and bronchodilation
smooth muscle contraction and bronchoconstriction
Circulating adrenaline from the adrena…
B2 receptors - results in an increase of cAMP causing smooth…
NANC innervation is
nonadrenergic noncholinergic - these include a variety of pep…
231 terms
Pharmacology
STUDY CONSIDERATIONS
Pharmaceutic Phases
4 stages of Pharmacokinetics:... 1. Absor…
1. Absorption (and factors)
INDICATIONS - why giving certain products?... INTERACTIONS... MONIT…
movement of drugs within the body
Movement of drugs from site of administration into vascular b…
STUDY CONSIDERATIONS
INDICATIONS - why giving certain products?... INTERACTIONS... MONIT…
Pharmaceutic Phases
169 terms
PHARMACOLOGY
Pharmacodynamics
Pharmacokinetics
Binding Forces
Receptor
-The study of what a drug does to the body... -pharmacologic eff…
-Movement of drugs in the body... -Drugs outside of body=>Drug i…
1. Covalent... 2. Ionic... 3. Hydrogen... 4. Hydrophobic... 5. Van der Wa…
-targets are only at certain places... -drugs can bind to enzyme…
Pharmacodynamics
-The study of what a drug does to the body... -pharmacologic eff…
Pharmacokinetics
-Movement of drugs in the body... -Drugs outside of body=>Drug i…
Pharmacology
PHARMOCOKINETICS:
PHARMACODYNAMICS:
PHARMACOTHERAPEUTICS:
Factors affect absorption
Absorption, distribution, metabolism, and excretion of drugs…
Biochemical and physical effects of the drug (what the drug d…
Use of drugs to prevent and treat disease (the reason we pres…
> Food or fluids administered with the drug... > Status of the a…
PHARMOCOKINETICS:
Absorption, distribution, metabolism, and excretion of drugs…
PHARMACODYNAMICS:
Biochemical and physical effects of the drug (what the drug d…
20 terms
Pharmacology
G protein linked Receptors
G protein linked 2nd messengers
Direct Muscarinic/Cholinomimetic Agoni…
Indirect Agonists=anticholinesterase
bethanecho: post-op/neurogenic ileus, urinary retention... carba…
increase ACh... Donepezil, galantamine, rivastigmine: Alzheimer…
G protein linked Receptors
G protein linked 2nd messengers
68 terms
Pharmacology
Calculate Vd
Calculate clearance (CL)
Calculate T1/2 in first order eliminat…
Calculate Loading Dose
Amount of drug in body/[in plasma]
= rate of elimination/[in plasma] ... =Vd*Elimination Constant
=0.693*Vd/CL
=[target at SS]*Vd/F... F=Bioavaliability
Calculate Vd
Amount of drug in body/[in plasma]
Calculate clearance (CL)
= rate of elimination/[in plasma] ... =Vd*Elimination Constant
21 terms
Pharmacology
Analgesic
Antipyretic
Anesthetic
Antacid
medicine to combat pain
reduces fever
Drug that prevents pain during surgery
neutralizes acid (Amphojel, Gelusil, Mylanta, Milk of Magnesia)
Analgesic
medicine to combat pain
Antipyretic
reduces fever
1 of 10