Study sets matching "pharmacology"

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Study sets matching "pharmacology"

Pharmacology
Enzyme Kinetics
Enzyme Kinetics (cont)
Enzyme Kinetics (cont x2)
Enzyme Kinetics (cont x3)
Enzyme Kinetics
Enzyme Kinetics (cont)
68 terms
Pharmacology
Inotropic effect?... Example?
Chronotropic effect?... Example?
Dromotropic effect... Example?
Treatment of heart muscle failure?
Force or energy of muscular contractions... Positive Inotropic d…
Rate of the heartbeat... Negative chronotropic drug
Conduction of electrical impulses... Negative dromotropic drug
Positive Inotropic Drug
Inotropic effect?... Example?
Force or energy of muscular contractions... Positive Inotropic d…
Chronotropic effect?... Example?
Rate of the heartbeat... Negative chronotropic drug
163 terms
Pharmacology
pharmacokinetics definition
pharmacodynamics definition
agonist
antagonist
study of how drug moves into, through, and out of body
study of how drug produces its effects in body
drug molecule has an effect on the cell "intrinsic activity"
combines with drug molecule and produces opposite affect of 1…
pharmacokinetics definition
study of how drug moves into, through, and out of body
pharmacodynamics definition
study of how drug produces its effects in body
60 terms
Pharmacology
alges/o
chem/o
cutane/o or derm/o
esthes/o
Sensitivity to pain
Drug
Skin
Feeling
alges/o
Sensitivity to pain
chem/o
Drug
6 terms
Pharmacology
concentration of a drug at steady state
calculate a maintenance dose
how many half lives to achieve steady…
volume of distribution
rate of drug into body over clearance
rearrange Css
4-5... ~93->96
concentration of a drug at steady state
rate of drug into body over clearance
calculate a maintenance dose
rearrange Css
80 terms
Pharmacology
Antihistamine
Anti-inflammatory; Corticosteriod
Anti-inflammatory; Corticosteriod
Anti-inflammatory; Corticosteriod
Chlorpheniramine Maleate
Deltasone; Prednisone
Dexamethasone Sodium Phosphate
Dexamathasone Solution
Antihistamine
Chlorpheniramine Maleate
Anti-inflammatory; Corticosteriod
Deltasone; Prednisone
88 terms
PHARMACOLOGY
Medications
pharmaceutics
pharmacokinetics
absorption
a substance administered for the diagnosis, cure, treatment,…
The science of dosage form design... example is tablets, capsule…
Study of how various dosage forms influence pharmokinetic and…
rate at which a drug leaves its site of administration and is…
Medications
a substance administered for the diagnosis, cure, treatment,…
pharmaceutics
The science of dosage form design... example is tablets, capsule…
Pharmacology
Phase II metabolism
Pharmacokinetics
Pharmacodynamics
Metabolism
Usually aid in elimination of the drug
'What the body does to the drug' ADME
'What the drug does to the body'
Usually reduces amount of active drug
Phase II metabolism
Usually aid in elimination of the drug
Pharmacokinetics
'What the body does to the drug' ADME
68 terms
Pharmacology
Calculate Vd
Calculate clearance (CL)
Calculate T1/2 in first order eliminat…
Calculate Loading Dose
Amount of drug in body/[in plasma]
= rate of elimination/[in plasma] ... =Vd*Elimination Constant
=0.693*Vd/CL
=[target at SS]*Vd/F... F=Bioavaliability
Calculate Vd
Amount of drug in body/[in plasma]
Calculate clearance (CL)
= rate of elimination/[in plasma] ... =Vd*Elimination Constant
21 terms
Pharmacology
Analgesic
Antipyretic
Anesthetic
Antacid
medicine to combat pain
reduces fever
Drug that prevents pain during surgery
neutralizes acid (Amphojel, Gelusil, Mylanta, Milk of Magnesia)
Analgesic
medicine to combat pain
Antipyretic
reduces fever
95 terms
pharmacology
chemical name
generic name
trade name
pharmacokinetics
describes the drug's chemical structure.
name given by health Canada ;starts with small letter
the drug has registered trademark; starts with capital letter
What the body does to the drug
chemical name
describes the drug's chemical structure.
generic name
name given by health Canada ;starts with small letter
13 terms
Pharmacology
PRN
AC
PC
Subcut meds are deposited in the loose…
As needed
Before meals
After meals
Dermis
PRN
As needed
AC
Before meals
pharmacology
chemical name
Valium
generic name
diazepam
name given for the atomic or molecular structure of a drug
tranquilizer
name given a drug which is not a proprietary name but the nam…
generic name for Valium
chemical name
name given for the atomic or molecular structure of a drug
Valium
tranquilizer
42 terms
Pharmacology
Sulfonamide Drug Examples
Sulfonamide When to Use
Sulfonamide Adverse Effects
Sulfonamide Labs to Monitor
SMX-TMP, Bactrim Septra
Use on organisms that synthesize folic acid, wide spectrum, U…
anemia, photosensitivity of the skin, dermatitis, Stephen-Joh…
?
Sulfonamide Drug Examples
SMX-TMP, Bactrim Septra
Sulfonamide When to Use
Use on organisms that synthesize folic acid, wide spectrum, U…
709 terms
Pharmacology
Multi-dose bottles
OTC meds
Drug absorption
first-pass effect... revise this!
Discard & get new bottle if soiled
Be aware that OTC meds may contain the same active medication…
Drug absorption is influenced by liver (hepatic) function. (1…
Hepatic degradation or alteration of a drug taken by mouth, a…
Multi-dose bottles
Discard & get new bottle if soiled
OTC meds
Be aware that OTC meds may contain the same active medication…
217 terms
Pharmacology
Pharmicological regulation is done by…
What is the definition of a drug?
What is a Schedule I drug?
What is a Schedule II drug?
Health products and food branch, Canadian food and drug act,…
used in the diagnosis,treatment,mitigation or prevention of a…
Narcotics
cannibis
Pharmicological regulation is done by…
Health products and food branch, Canadian food and drug act,…
What is the definition of a drug?
used in the diagnosis,treatment,mitigation or prevention of a…
378 terms
Pharmacology
Pharmacology
Pharmacotherapy
Phase 1 study
Phase 2 study
The study if the biological effects of chemicals
Clinical pharmacology; branch of pharmacology that deals with…
Pilot study of a potential drug done with a small number of h…
Clinical study of a proposed drug by selected physicians usin…
Pharmacology
The study if the biological effects of chemicals
Pharmacotherapy
Clinical pharmacology; branch of pharmacology that deals with…
709 terms
Pharmacology
Multi-dose bottles
OTC meds
Drug absorption
first-pass effect... revise this!
Discard & get new bottle if soiled
Be aware that OTC meds may contain the same active medication…
Drug absorption is influenced by liver (hepatic) function. (1…
Hepatic degradation or alteration of a drug taken by mouth, a…
Multi-dose bottles
Discard & get new bottle if soiled
OTC meds
Be aware that OTC meds may contain the same active medication…
88 terms
PHARMACOLOGY
Medications
pharmaceutics
pharmacokinetics
absorption
a substance administered for the diagnosis, cure, treatment,…
The science of dosage form design... example is tablets, capsule…
Study of how various dosage forms influence pharmokinetic and…
rate at which a drug leaves its site of administration and is…
Medications
a substance administered for the diagnosis, cure, treatment,…
pharmaceutics
The science of dosage form design... example is tablets, capsule…
39 terms
Pharmacology
Agonists
Antagonist
Stereoisomers
Beta-blockers
Stimulants
Blocks
Mirror image
Blood pressure
Agonists
Stimulants
Antagonist
Blocks
10 terms
Pharmacology
methotrexate
TNF-Alpha inhibitor
Inhaled steroids won't have Cushing sy…
aspirin allergy might cause asthma, wh…
Inhibits FH2---FH4, anti tumor, immune suppression
PrePosed to TB
...
...
methotrexate
Inhibits FH2---FH4, anti tumor, immune suppression
TNF-Alpha inhibitor
PrePosed to TB
51 terms
Pharmacology
Analgesic
Anesthetic
Antacid
Antianxiety
An agent that relieves pain without causing loss of conscious…
An agent that produces a lack of feeling. May be local or gen…
An agent that neutralizes acid.
An agent that relieves anxiety and muscle tension.
Analgesic
An agent that relieves pain without causing loss of conscious…
Anesthetic
An agent that produces a lack of feeling. May be local or gen…
506 terms
Pharmacology
Selective Cox-2 inhibitors
Neuroleptic malignant Syndrome
Modafinil
Tetracyclines
eg. celecoxib. ... Cox-2 is an inducible enzyme that is unregul…
adverse reaction to antipsychotic medication characterized by…
first line treatment for narcolepsy. ... Amphetamines are secon…
are teratogenic and can cause fetal bone growth retardation a…
Selective Cox-2 inhibitors
eg. celecoxib. ... Cox-2 is an inducible enzyme that is unregul…
Neuroleptic malignant Syndrome
adverse reaction to antipsychotic medication characterized by…
Pharmacology
definition of a drug, examples
pharmacodynamics vs pharmacokinetics
agonist & biased agonism (aka agonist…
antagonist vs indirect antagonist
broad definition: chemical substance alters physical/mental w…
pharmacodynamics- action of a drug on the body; therapeutic/t…
binds to receptor and produces biological response... biased ag…
direct antagonist- binds to receptor but doesn't produce biol…
definition of a drug, examples
broad definition: chemical substance alters physical/mental w…
pharmacodynamics vs pharmacokinetics
pharmacodynamics- action of a drug on the body; therapeutic/t…
59 terms
Pharmacology
Propranolol
Strongest bond
weakest bond
Law of Mass Action
beta-adrenergic antagonist... blocks the action of epinephrine a…
ionic
van der waals
Rate of Association=K1[C][R]... Rate of Dissociation=k-1[CR]
Propranolol
beta-adrenergic antagonist... blocks the action of epinephrine a…
Strongest bond
ionic
54 terms
Pharmacology
Phase I trials
Phase II tirals
Phase III Trials
Time and Money for new drug
volunteers (≈20-80)... Efficacy is not studied... Determines safety…
Studies a small number of patients with the targeted disease…
Large, multi-site sample of patients (hundreds to thousands)…
$359 million ... It takes approximately 12 years to develop ... O…
Phase I trials
volunteers (≈20-80)... Efficacy is not studied... Determines safety…
Phase II tirals
Studies a small number of patients with the targeted disease…
322 terms
Pharmacology
Neonatal animals are less tolerant of…
Decreased function of what organ would…
Generic name for a drug is also called:
You're asked to dminister a drug that…
Biotransformed (metabolized) more slowly
Liver
Nonproprietary name
Order or purchase 25 mg tabs for dosing schedule
Neonatal animals are less tolerant of…
Biotransformed (metabolized) more slowly
Decreased function of what organ would…
Liver
98 terms
Pharmacology
Which statement describes how to conve…
Which is the correct metric weight for…
Which term means to change from one un…
During an emergency situation, a patie…
Move the decimal point three spaces to the right
75 kg
Convert
Intramuscular
Which statement describes how to conve…
Move the decimal point three spaces to the right
Which is the correct metric weight for…
75 kg
40 terms
pharmacology
Lists the parts of the Nervous system.…
The ANS all have distal ______, and my…
The ANS has what two neurotransmitters?
NE has how many types of receptors?
the NS is broken into the CNS and PNS. The CNS includes the b…
ganglia, PREganglion, POST-, NON-myelinated, myelinated.
Acetylcholine (ACH) and Norepinephrine (NE).
5: alpha 1, 2, beta 1-3.
Lists the parts of the Nervous system.…
the NS is broken into the CNS and PNS. The CNS includes the b…
The ANS all have distal ______, and my…
ganglia, PREganglion, POST-, NON-myelinated, myelinated.
40 terms
Pharmacology
Narcotics do not:
antihypertensives control blood pressu…
the medical assistant's list of common…
which class of antiarrhythmic drugs in…
cause hyperactivity
inhibiting conversion of angiotensin 1 into angiotensin 2
usual dosage, possible side effects, contraindications
class III
Narcotics do not:
cause hyperactivity
antihypertensives control blood pressu…
inhibiting conversion of angiotensin 1 into angiotensin 2
Pharmacology
What drug from the Benzodiazepine clas…
Acts in the limbic system and reticula…
Are drugs which depress or slow down t…
The ___???______ enhance the action of…
Xanax
Diazepam
Hypnotics
Benzodiazepine
What drug from the Benzodiazepine clas…
Xanax
Acts in the limbic system and reticula…
Diazepam
Pharmacology
-conazoles
-mab
cef- (ceph-)
-pril
antifungal
monoclonal antibody
cephalosporin antibiotics
angiotensin converting enzyme (ACE) inhibitors
-conazoles
antifungal
-mab
monoclonal antibody
52 terms
Pharmacology
How should NSAIDs be administered
What is the drug classification for Ba…
Can you just stop taking Benzodiazepine?
What must you take with any type of Na…
Must be taken with food
Anticonvulsants
Most be tapered or can cause seizures
Stool Softener because it can make them constipated
How should NSAIDs be administered
Must be taken with food
What is the drug classification for Ba…
Anticonvulsants
32 terms
Pharmacology
Five rights of medication
Affinity
Blood Brain Barrier
Pharmacognosy
medication, dose, frequency, route, patient
how strong a med with bind with the receptor site
semipermeable membrane between blood and brains very specific…
study of drugs obtained from natural plant/animal sources
Five rights of medication
medication, dose, frequency, route, patient
Affinity
how strong a med with bind with the receptor site
7 terms
Pharmacology
Preoxygenation, or perhaps more accura…
Mannitol is classified as a/an _______…
The______________ is composed of tufts…
Symptoms of hyponatremia during a TURP…
ANSWER: Denitrogenation... EXPLANATION:... This procedure entails…
ANSWER: osmotic... EXPLANATION:... Mannitol is the most commonly u…
ANSWER: glomerulus... EXPLANATION: ... The glomerulus is composed…
ANSWER: 120 mEq/L... EXPLANATION: ... Symptoms of hyponatremia usu…
Preoxygenation, or perhaps more accura…
ANSWER: Denitrogenation... EXPLANATION:... This procedure entails…
Mannitol is classified as a/an _______…
ANSWER: osmotic... EXPLANATION:... Mannitol is the most commonly u…
Pharmacology
Clearance of drug calculation
How long does a drug infused at a cons…
Half life calculation
Loading dose calculation
Clearance = Volume of plasma clear of drug/per unit time ... CL…
4-5 half lives... Independent of dose and dosing frequency
= 0.693 x Volume of distribution/CL
Where Cp is the desired plasma concentration and F is the fre…
Clearance of drug calculation
Clearance = Volume of plasma clear of drug/per unit time ... CL…
How long does a drug infused at a cons…
4-5 half lives... Independent of dose and dosing frequency
38 terms
pharmacology
.. The nurse is explaining to the pati…
. 1. ID: 310993981 Which action should…
The nurse identifies crepitus when exa…
The nurse prepares to change a patient…
Nonspecific drugs require higher doses than specific drugs to…
A Have the client empty her bladder. Correct
B Observe for an asymmetrical Moro (startle) reflex. Correct
A bioavailability.
.. The nurse is explaining to the pati…
Nonspecific drugs require higher doses than specific drugs to…
. 1. ID: 310993981 Which action should…
A Have the client empty her bladder. Correct
Pharmacology
A nurse is administering donepezil (Ar…
A nurse is caring for an older adult c…
A nurse is providing teaching to a cli…
A nurse is teaching a client who is to…
Dyspnea
B. 0.9% sodium chloride 1 L IV infused over 4hr. Vital signs…
I should let my dentist know I'm taking this medication.
Change positions slowly
A nurse is administering donepezil (Ar…
Dyspnea
A nurse is caring for an older adult c…
B. 0.9% sodium chloride 1 L IV infused over 4hr. Vital signs…
Pharmacology
Pharmacology
Pharmacodynamics
Pharmacokinetics
Why is pharmacology important for nurs…
the scientific study of drugs and how they are used in medicine
what the drug does to the body... - the mechanism of action, cel…
what the body does to a drug ... - what factors determine the ma…
-administering drugs... -assessing drug effects... -intervening to…
Pharmacology
the scientific study of drugs and how they are used in medicine
Pharmacodynamics
what the drug does to the body... - the mechanism of action, cel…
54 terms
pharmacology
DRUG DOSAGE MEANS
PHARMACOLOGY MEANS
TO ADMINISTER A DRUG MEANS TO
OTC
the amount of medication in a single dose
study of the drugs,their uses, and their interations in livin…
GIVE THAT MEDICATION
OVER THE COUNTER
DRUG DOSAGE MEANS
the amount of medication in a single dose
PHARMACOLOGY MEANS
study of the drugs,their uses, and their interations in livin…
Pharmacology
pharmacology
pharmacokinetics
A drug has to pass the blood brain bar…
absorption
study of drugs
movement of the drugs through the circulatory system, across…
the CNS
the means by which the drug enters the circulatory system
pharmacology
study of drugs
pharmacokinetics
movement of the drugs through the circulatory system, across…
pharmacology
Which member of the surgical tema must…
List the five rights of medication adm…
Medication labels must contain all of…
Improper or inadequate labeling of med…
The circulator
Right drug, right dose, right route, right patient, right time
contraindications
malpractice
Which member of the surgical tema must…
The circulator
List the five rights of medication adm…
Right drug, right dose, right route, right patient, right time
pharmacology
antiemetic
antidiarrheal
laxative
antiacid
vomiting
diarrhea
constipation
gas
antiemetic
vomiting
antidiarrheal
diarrhea
Pharmacology
What is the name under which a drug is…
Which source contains information spec…
What is the most comprehensive referen…
The physician has written an order for…
C. Official
C. United States Pharmacopeia/National Formulary (USP-NF)
B. Drug Interaction Facts
B. Brand and Generic Name section
What is the name under which a drug is…
C. Official
Which source contains information spec…
C. United States Pharmacopeia/National Formulary (USP-NF)
142 terms
Pharmacology
Hydrochlorothiazide (HCTZ), Chlorthali…
Furosemide, Bumetanide, Torsemide
Clonidine
Methyldopa
Subclass: Diuretic (thiazide)... MOA: blocks Na/Cl transporter…
Subclass: Diuretic (loop)... MOA: blocks Na/K/2Cl transporter i…
Subclass: Sympathoplegic (Central acting)... MOA: alpha-2 recep…
Subclass: Sympathoplegic (Centrally acting)... MOA: alpha-2 rec…
Hydrochlorothiazide (HCTZ), Chlorthali…
Subclass: Diuretic (thiazide)... MOA: blocks Na/Cl transporter…
Furosemide, Bumetanide, Torsemide
Subclass: Diuretic (loop)... MOA: blocks Na/K/2Cl transporter i…
Pharmacology
Desyrel
Soma
Ovral lo-ovral
Micronase diabeta
Trazodone... Anti depressants ... Dna
Carisoprodone... Muscle relaxer... Dna
Birth control
Glyburide... Anti-diabetic... DnA/twf
Desyrel
Trazodone... Anti depressants ... Dna
Soma
Carisoprodone... Muscle relaxer... Dna
188 terms
Pharmacology
Hypertension
Hypertension Epidemiology
Blood Pressure Range
Hypertension - Etiology
28% American Adults... Asymptomatic until overt end-organ damage…
Smoking... Metabolic syndrome... Obesity... Dyslipidemia... Diabetes... Orga…
Normal <120/80... Prehypertension - 120-135/80-89... Hypertension -…
Only found in 10-15%... Renal artery constriction... Coarctation of…
Hypertension
28% American Adults... Asymptomatic until overt end-organ damage…
Hypertension Epidemiology
Smoking... Metabolic syndrome... Obesity... Dyslipidemia... Diabetes... Orga…
Pharmacology
Analgesic
Antipyretic
Anesthetic
Antibiotic
Drug to relieve pain
Drug to reduce fever
Drug which produce insensibility to pain
Drug which is effective against bacterial infections
Analgesic
Drug to relieve pain
Antipyretic
Drug to reduce fever
28 terms
Pharmacology
Lineweaver-burk plot
Volume of Distribution
Zero order elimination
First order elimination
1) Km is inversely related to the affinity of an enzyme for…
Vd = (amount of drug in body)/ (plasma drug concentration)... 1…
Rate of drug elimination is independent of its plasma concent…
Rate of drug elimination is a constant fraction, depending on…
Lineweaver-burk plot
1) Km is inversely related to the affinity of an enzyme for…
Volume of Distribution
Vd = (amount of drug in body)/ (plasma drug concentration)... 1…
27 terms
Pharmacology
The nonproprietary name is also known…
The proprietary name is known as the _…
The time course of drug concentrations…
_______ is known as what the drug does…
Generic
Brand
Pharmacokinetics
Pharmacodynamics
The nonproprietary name is also known…
Generic
The proprietary name is known as the _…
Brand
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