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Study sets matching "pharmacology"

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Study sets matching "pharmacology"

34 terms
Pharmacology
Drug absorption of or preparations
Dosage forms
Bioequivalent
Gastric dumping
When 2 drug products have the same bioavailability & same con…
Result of bariatric weight-loss surgery that reduces the size…
Drug absorption of or preparations
Dosage forms
52 terms
Pharmacology
How should NSAIDs be administered
What is the drug classification for Ba…
Can you just stop taking Benzodiazepine?
What must you take with any type of Na…
Must be taken with food
Anticonvulsants
Most be tapered or can cause seizures
Stool Softener because it can make them constipated
How should NSAIDs be administered
Must be taken with food
What is the drug classification for Ba…
Anticonvulsants
641 terms
Pharmacology
Agonist
Antagonist
Different ways drugs act
What are the local routes of administr…
Substances that mimic endogenous substances
Connects to a receptor in order to block activation of hormone
Act by inhibiting enzymes, block transporters, agonist, and a…
Topical, ophthalmic, otic, intranasal, inhalation, intratheca…
Agonist
Substances that mimic endogenous substances
Antagonist
Connects to a receptor in order to block activation of hormone
98 terms
Pharmacology
Which statement describes how to conve…
Which is the correct metric weight for…
Which term means to change from one un…
During an emergency situation, a patie…
Move the decimal point three spaces to the right
75 kg
Convert
Intramuscular
Which statement describes how to conve…
Move the decimal point three spaces to the right
Which is the correct metric weight for…
75 kg
56 terms
Pharmacology
pharmacology
pharmacologist
pharmacist
analgesic
study of drugs
medical professional with additional phd - develops and studi…
licensed to prepare and dispense drugs and compounds.
substance that reduces pain sensation
pharmacology
study of drugs
pharmacologist
medical professional with additional phd - develops and studi…
55 terms
Pharmacology
Pharmacology
Drug
Target Tissue
Absorption
the study of drugs and their uses
chemicals; used to diagnosis, treatment and prevention
where we want the drug to act in the body
take up of drug into the blood stream to target tissue
Pharmacology
the study of drugs and their uses
Drug
chemicals; used to diagnosis, treatment and prevention
45 terms
Pharmacology
trade/brand name
indications
contraindications
DEA
licensed name under which a drug prepared by a specific manuf…
diseases and disorders for which a certain drug may be used
conditions in which the use of a certain drug is dangerous or…
Drug Enforcement Administration, since 1973, the only legal U…
trade/brand name
licensed name under which a drug prepared by a specific manuf…
indications
diseases and disorders for which a certain drug may be used
40 terms
Pharmacology
ac
aq
bid
cap
Before meals
Water
Twice a day
capsule
ac
Before meals
aq
Water
152 terms
Pharmacology
Enzyme Kinetics
Enzyme Kinetics (cont)
Enzyme Kinetics (cont x2)
Enzyme Kinetics (cont x3)
Enzyme Kinetics
Enzyme Kinetics (cont)
46 terms
Pharmacology
EC50
A. A is the most potent... B. Both A and…
Agonist
Partial agonist
Measure of the potency of a drug. Dose of drug that gives 50%…
A. Which drug is most potent?... B. Which drug is most effective?
Reduces positive response by reducing proportion of receptors…
Even at high concentration it cannot act as full agonist- low…
EC50
Measure of the potency of a drug. Dose of drug that gives 50%…
A. A is the most potent... B. Both A and…
A. Which drug is most potent?... B. Which drug is most effective?
10 terms
pharmacology
Optimum CNS penetration around Log P
Optimum Oral absorption around Log P
Optimum Intestinal absorption Log P
Optimum Colonic absorption LogP
2 +/- 0.7
1.8
1.35
1.32
Optimum CNS penetration around Log P
2 +/- 0.7
Optimum Oral absorption around Log P
1.8
14 terms
pharmacology
gr
cc
gtt
change
grain
cubic centimeters
drop
triangle
gr
grain
cc
cubic centimeters
27 terms
Pharmacology
Prescription Drugs
Controlled Substance
Pharmacokinetics
Half-life of drug
Must be prescribed by a licensed person, MD, PA, NP
Most carefully monitored, most likely to be counted medicatio…
Effect of the drug on the body- ... phases:absorption, distribut…
time span needed for one half of the individual drug dose giv…
Prescription Drugs
Must be prescribed by a licensed person, MD, PA, NP
Controlled Substance
Most carefully monitored, most likely to be counted medicatio…
113 terms
Pharmacology
3 types of delivery systems of drugs
Implantable intraocular drug delivery…
Topical drugs
Solutions
topical , injections , oral systems
diffuses meds through the sclera + into eye
liquid drops in the form of solutions, suspensions, and ointm…
completely dissolved in an inert liquid "vehicle" such as ste…
3 types of delivery systems of drugs
topical , injections , oral systems
Implantable intraocular drug delivery…
diffuses meds through the sclera + into eye
54 terms
pharmacology
DRUG DOSAGE MEANS
PHARMACOLOGY MEANS
TO ADMINISTER A DRUG MEANS TO
OTC
the amount of medication in a single dose
study of the drugs,their uses, and their interations in livin…
GIVE THAT MEDICATION
OVER THE COUNTER
DRUG DOSAGE MEANS
the amount of medication in a single dose
PHARMACOLOGY MEANS
study of the drugs,their uses, and their interations in livin…
104 terms
Pharmacology
Federal law requires that all controll…
The inscription of the prescription is:
A(n)________ is an agent the relieves…
Substances that prevent or inhibit the…
Stored in a substantially constructed metal box that has a do…
Name of the drug(s) and the amount
Analgesic
Antibiotics
Federal law requires that all controll…
Stored in a substantially constructed metal box that has a do…
The inscription of the prescription is:
Name of the drug(s) and the amount
183 terms
Pharmacology
General characteristics of drugs
treatment (of a disease)
mitigation
prevention
...
leczenie
łagodzenie
zapobieganie
General characteristics of drugs
...
treatment (of a disease)
leczenie
44 terms
pharmacology
pharmacotherapeutics
nursing responsibilities
Legal/Ethical Considerations
Rs of Drug Administration
the use of drugs to prevent or treat disease
1- administer drug by using 10 Rs... 2- assessing dug effects…
> control of drug development... > evaluation (pre-clinical tri…
> right drug... > right PT... > right route... > right dosage... > ri…
pharmacotherapeutics
the use of drugs to prevent or treat disease
nursing responsibilities
1- administer drug by using 10 Rs... 2- assessing dug effects…
152 terms
Pharmacology
Enzyme Kinetics
Enzyme Kinetics (cont)
Enzyme Kinetics (cont x2)
Enzyme Kinetics (cont x3)
Enzyme Kinetics
Enzyme Kinetics (cont)
Pharmacology
Penicillin (P: Ampicillin)
Cephalosporins (P: Cefazolin)
Aminoglycosides (P: Gentamicin)
Fluoroquinolones (P: ciprofloxacin)
Skin, soft tissue, respiratory GI, and GU infections. ... Can be…
Use: Respiratory tract, skin and soft tissues, bones and join…
-serious infection gram (-). septicemia, respiratory tract in…
-most potent against gram (-). acute sinusitis, lower respira…
Penicillin (P: Ampicillin)
Skin, soft tissue, respiratory GI, and GU infections. ... Can be…
Cephalosporins (P: Cefazolin)
Use: Respiratory tract, skin and soft tissues, bones and join…
869 terms
Pharmacology
What are the major functions of the α1…
What are the major functions of the α2…
What are the major functions of the β1…
What are the major functions of the β2…
Increase vascular smooth muscle contraction, increase pupilla…
Decrease sympathetic outflow, decrease insulin release, decre…
Increase heart rate, increase contractility, increase renin r…
Vasodilation, bronchodilation, increase lipolysis, increase i…
What are the major functions of the α1…
Increase vascular smooth muscle contraction, increase pupilla…
What are the major functions of the α2…
Decrease sympathetic outflow, decrease insulin release, decre…
166 terms
Pharmacology
STUDY CONSIDERATIONS
Pharmaceutic Phases
Pharmacokinetics
4 Characteristics of Pharmacokinetics
INDICATIONS - why giving certain products?... INTERACTIONS... MONIT…
movement of drugs within the body
1. Absorption... 2. Distribution... 3. Metabolism (AKA biotransform…
STUDY CONSIDERATIONS
INDICATIONS - why giving certain products?... INTERACTIONS... MONIT…
Pharmaceutic Phases
22 terms
PHARMACOLOGY
ANTIFOLATES MOA
MTX - ROUTE OF ELIMINATION
MTX TOXICITY
HIGH DOSE MTX NEUROTOXICITY
INHIBITION OF DIHYDROFOLATE REDUCTASE ( DHFR) RESULTING IN DE…
RENAL
MYELOSUPPRESSION... GI- MUCOSITIS... NEPHROTOXICITY - IV HYDRATION…
ACUTE ENCEPHALOPATHY - WITHIN 6 DAYS, RESOLVES WITHIN 48-72 H…
ANTIFOLATES MOA
INHIBITION OF DIHYDROFOLATE REDUCTASE ( DHFR) RESULTING IN DE…
MTX - ROUTE OF ELIMINATION
RENAL
21 terms
Pharmacology
Kd
Fractional occupancy (f)
EC50
Effect of partial agonist
[D][R]/[DR]. Low Kd = high affinity
[DR]/[Total R] = [D]/[D]+Kd
[] of drug needed for half-maximal effect
Lowers maximum effect
Kd
[D][R]/[DR]. Low Kd = high affinity
Fractional occupancy (f)
[DR]/[Total R] = [D]/[D]+Kd
35 terms
Pharmacology
adverse reaction
anaphylactic shock
bacteriostatic
buccal medication
body's reaction to drug in unexpected way that may endanger p…
life threating hypersensitive reaction to food or drugs. pati…
stopping or controlling growth of bacteria
placed in mouth next to cheek, where it's absorbed into mucou…
adverse reaction
body's reaction to drug in unexpected way that may endanger p…
anaphylactic shock
life threating hypersensitive reaction to food or drugs. pati…
5 terms
Pharmacology
Lipitor
Synthroid
Glucophage
Nexium
Atorvastatin... Cholesterol
Levothyroxine
Metforming
Esomeprazole
Lipitor
Atorvastatin... Cholesterol
Synthroid
Levothyroxine
100 terms
Pharmacology
pharmacology
drug
medicine
side effect
study of all drugs, their properties, how they react with eac…
substance that can change life's processes
used to treat diseases
unintended result
pharmacology
study of all drugs, their properties, how they react with eac…
drug
substance that can change life's processes
13 terms
Pharmacology
Ondansetron
Dexamethasone
Metoclopropamide
Loperamide
Zofran
Decadron
Reglan
Imodium
Ondansetron
Zofran
Dexamethasone
Decadron
14 terms
Pharmacology
A nurse is administering donepezil (Ar…
A nurse is caring for an older adult c…
A nurse is providing teaching to a cli…
A nurse is teaching a client who is to…
Dyspnea
B. 0.9% sodium chloride 1 L IV infused over 4hr. Vital signs…
I should let my dentist know I'm taking this medication.
Change positions slowly
A nurse is administering donepezil (Ar…
Dyspnea
A nurse is caring for an older adult c…
B. 0.9% sodium chloride 1 L IV infused over 4hr. Vital signs…
39 terms
Pharmacology
Absorption physiological
pharmacokinetics
pharmacodynamics
bindings sites
Swallow food... Proteins are broken down by enzymes in the gut t…
What the body does to the drug: Absorption, Distribution, Met…
What the drug does to the body
enzymes, ion channels, carrier transporter, carrier pumps, re…
Absorption physiological
Swallow food... Proteins are broken down by enzymes in the gut t…
pharmacokinetics
What the body does to the drug: Absorption, Distribution, Met…
41 terms
Pharmacology
Apothecary system
Clarks rule
Denominator
Fraction bar
Oldest system of measurement
Based on the weight of the child
Bottom number of a fraction
Separates the numerator and denominator
Apothecary system
Oldest system of measurement
Clarks rule
Based on the weight of the child
5 terms
Pharmacology
methotrexate
TNF-Alpha inhibitor
Inhaled steroids won't have Cushing sy…
aspirin allergy might cause asthma, wh…
Inhibits FH2---FH4, anti tumor, immune
PrePosed to TB
...
...
methotrexate
Inhibits FH2---FH4, anti tumor, immune
TNF-Alpha inhibitor
PrePosed to TB
28 terms
Pharmacology
Quinidine
Propafenone
Lidocaine
Adenosine
Quinidine
Propafenone
8 terms
pharmacology
the action of phrmacokinetics
metabolism, excretion
absorption
passive diffusion
absorption, distribution, metabolism, excretion
drug elimination or clearance mechanism
time the drug enters the body to the time it enters the bodys…
movement of a drug from an area of higher concentration to on…
the action of phrmacokinetics
absorption, distribution, metabolism, excretion
metabolism, excretion
drug elimination or clearance mechanism
101 terms
Pharmacology
Pharmacology
Pharmacokinetics associated with
Pharmacodynamics associated with
Before a drug can begin to exert any e…
. the study of drugs (chemicals) and their interactions with…
. ADME
. Receptor binding... . Signal transduction ... . Physiologic effect
. absorbed
Pharmacology
. the study of drugs (chemicals) and their interactions with…
Pharmacokinetics associated with
. ADME
40 terms
Pharmacology
Pharmacology: -adol
Pharmacology: -one,-done
Pharmacology: -ane
Pharmacology: -caine
analgesics-opioid... ex. tramadol... ass. with the 6 D's-... depress…
analgesics-opioid... ex. hydrocodone (norco, vicodin); hydromor…
anesthetics-general... cyclohexane, ethane, flurane... used in th…
anesthetics-Local/antiarrhythmics-class 1... Ex. bupivacaine, co…
Pharmacology: -adol
analgesics-opioid... ex. tramadol... ass. with the 6 D's-... depress…
Pharmacology: -one,-done
analgesics-opioid... ex. hydrocodone (norco, vicodin); hydromor…
81 terms
Pharmacology
Drug Dosage
Pharmacology
To administer a drug
OTC
Amount of medication in a single dose
Study of drugs, their uses, and their interactions in living…
Give that medication
Over the Counter
Drug Dosage
Amount of medication in a single dose
Pharmacology
Study of drugs, their uses, and their interactions in living…
36 terms
Pharmacology
Pharmacology
Pharmadynamics
receptors
agonists
The study of drugs their actions on living organisims
The study of drugs interactions including the drug receptors…
sites on the cells where chemical bonding of drugs occurs are…
drugs that stimulate a response at a receptor site
Pharmacology
The study of drugs their actions on living organisims
Pharmadynamics
The study of drugs interactions including the drug receptors…
32 terms
Pharmacology
pharmacology
pharmacokinetics
A drug has to pass the blood brain bar…
absorption
study of drugs
movement of the drugs through the circulatory system, across…
the CNS
the means by which the drug enters the circulatory system
pharmacology
study of drugs
pharmacokinetics
movement of the drugs through the circulatory system, across…
31 terms
Pharmacology
Pharmacodynamics
Pharmacokinetics
xenobiotic
toxicant
action of drugs
movement of drugs
foreign substance taken into the body
substances that produce adverse (bad impact) biological effect
Pharmacodynamics
action of drugs
Pharmacokinetics
movement of drugs
168 terms
Pharmacology
Km
Vmax
Hyperbolic curve
Sigmoid curve
Inversely related to the affinity of the enzyme for its subst…
Directly proportional to the enzyme concentration
Michaelis Menten Kinetics
Cooperative kinetics
Km
Inversely related to the affinity of the enzyme for its subst…
Vmax
Directly proportional to the enzyme concentration
8 terms
Pharmacology
Shock, cardiac arrest and anaphylaxis…
Antianxiety agents
Digoxin (lanoxin)
SSRI
Norepinephrine: H/A, HTN... Dopamine: increased ocular pressure,…
Chlordiazepoxide (librium)- both: hypotension,↓ wbc (agranulo…
indic: HF, a fib, paroxysmal atrial tachy... action: ↑ calcium i…
Sertraline (zoloft)... Fluoxetine (Prozac)... Paroxetine (paxil)... a…
Shock, cardiac arrest and anaphylaxis…
Norepinephrine: H/A, HTN... Dopamine: increased ocular pressure,…
Antianxiety agents
Chlordiazepoxide (librium)- both: hypotension,↓ wbc (agranulo…
Pharmacology
Adrenergic
amino salicylates
anesthetics
antiarrhythmic
used to dilate the pupils, increase heart rate strengthen hea…
help treat inflammation
reduce sensation of pain
to treat arrhythmias
Adrenergic
used to dilate the pupils, increase heart rate strengthen hea…
amino salicylates
help treat inflammation
118 terms
Pharmacology
Calcium channel blockers
Hydralazine
Tx hypertensive emergency
Nitroglycerine
Dihydropyridine: amlodipine, nifedipine... Non-dihydro: diltiaze…
Hypertension in pregnancy... Incr. cGMP > vasodilates arterioles…
Nitroprusside... cGMP > NO
Angina... Incr NO > cGMP > dilate VEINS > decr preload
Calcium channel blockers
Dihydropyridine: amlodipine, nifedipine... Non-dihydro: diltiaze…
Hydralazine
Hypertension in pregnancy... Incr. cGMP > vasodilates arterioles…
10 terms
Pharmacology
DEA
Administer
Dispense
Narcotic
Demise
To manage , to conduct , as in business
To distribute ; to deal out in portions .
A drug capable of producing sleep and relieving pain or induc…
DEA
Demise
Administer
To manage , to conduct , as in business
78 terms
Pharmacology
****Antibiotics****
Penicillin
Beta Lactamase Inhibitors
Aminopenicillin Mechanism
...
(picmonic)
(picmonic)
(picmonic)
****Antibiotics****
...
Penicillin
(picmonic)
Pharmacology
Absorption
Acromion Process
Action
Administer
Passage of a substance through some surface of the body into…
An extension of the shoulder blade
How a drug acts in the body
To instill a drug onto the body of a patient
Absorption
Passage of a substance through some surface of the body into…
Acromion Process
An extension of the shoulder blade
87 terms
Pharmacology
Subscription
Superscription
Inscription
Signature
Contains directions to the pharmacist to include the size of…
Includes the date, patient's name, address, and the Rx symbol
The name of the drug and amount (strength)
Refers to the patient's instructions, usually following sig:
Subscription
Contains directions to the pharmacist to include the size of…
Superscription
Includes the date, patient's name, address, and the Rx symbol
239 terms
Pharmacology
Zero-order elimination
Notable drugs with zero-order eliminat…
First-order elimination
Vmax
Constant amount of drug eliminated per unit of time... Eliminati…
Phenytoin... Ethanol... Aspirin... "A PEA has zero calories"
Constant fraction of drug eliminated per unit of time... Elimina…
Point of enzyme saturation indicating maximum reaction rate
Zero-order elimination
Constant amount of drug eliminated per unit of time... Eliminati…
Notable drugs with zero-order eliminat…
Phenytoin... Ethanol... Aspirin... "A PEA has zero calories"
152 terms
Pharmacology
Enzyme Kinetics
Enzyme Kinetics (cont)
Enzyme Kinetics (cont x2)
Enzyme Kinetics (cont x3)
Enzyme Kinetics
Enzyme Kinetics (cont)
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