Study sets matching "pharmocology i"

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Study sets matching "pharmocology i"

422 terms
Pharmacology 1
biochemical, physiological effects/mec…
absorption, distribution, metabolism,…
FDA
scheduled drugs only
Pharmacodynamics (definition)
Pharmacokinetics (definition)
what US entity regulates drugs?
when should the DEA number be included in a prescription?
biochemical, physiological effects/mec…
Pharmacodynamics (definition)
absorption, distribution, metabolism,…
Pharmacokinetics (definition)
13 terms
Pharmacology #1
Pharmacology
Healers
Penicillin
Alternative Medicine
Study of Medicine
Wise men, Shamans, witch doctors , medicine men and women in…
early antibiotic that healed infections during WWii.
homeopathic sources such as aromatherapy, massage, and acupun…
Pharmacology
Study of Medicine
Healers
Wise men, Shamans, witch doctors , medicine men and women in…
9 terms
Pharmacology 1
Voltage Gated Na Channel... 6 transmembra…
Inward Rectifying K+ channel... 4 small s…
Voltage Gated K+ Channel... 4 subunits ea…
Voltage gated Ca2+ Channel... 6 mambrane…
Identify the channel type
Identify the channel
Identify the channel
Identify the Channel
Voltage Gated Na Channel... 6 transmembra…
Identify the channel type
Inward Rectifying K+ channel... 4 small s…
Identify the channel
57 terms
Pharmacology 1
Ginkgo Biloba (herbal med)
St. John's Wort (herbal med)
Saw Palmetto (herbal med)
Echinacea (herbal med)
treats poor memory and mild dementia
treats depression
treats enlarged prostate
treats the common cold
Ginkgo Biloba (herbal med)
treats poor memory and mild dementia
St. John's Wort (herbal med)
treats depression
62 terms
1 Pharmacology
pharmacology
Drug broad
Drug (specific) (3)
pharmakon
medical branch studies 1 interaction of drugs in living anima…
any chemical agent that affects living processes
1) a chem. substance that affects the processes of the mind o…
pharmacology greek word magic charm for treating disease... late…
pharmacology
medical branch studies 1 interaction of drugs in living anima…
Drug broad
any chemical agent that affects living processes
141 terms
PHARMACOLOGY 1 TEST 1
pharmacology
pharmacokinetics
pharmacoeconomics
toxicology
the study of the effect of chemicals on living tissue.
the study of the absorption, distribution, metabolism and exc…
the study of the economic impact of drugs
the study of the harmful effects of chemicals.
pharmacology
the study of the effect of chemicals on living tissue.
pharmacokinetics
the study of the absorption, distribution, metabolism and exc…
PHARMACOLOGY 1 - Test 3
acyclovir (Zovirax)
Prevent viral DNA replication and vira…
Prevent or delay spread of viral infec…
nephrotoxicity
Prototype drug for antivirals used to treat herpes simplex an…
Mechanism of action for acyclovir
Indication for acyclovir (Zovirax)
If Zovirax (acyclovir) is given IV, what is a potential side…
acyclovir (Zovirax)
Prototype drug for antivirals used to treat herpes simplex an…
Prevent viral DNA replication and vira…
Mechanism of action for acyclovir
87 terms
Pharmacology 1
Pure Food and Drug Act
Food Drug and Cosmetic Act
OBRA/HCFA Guidelines
Best Pharmaceuticals for Children Act
FDA can enforce the standards to drug STRENGTH and PURITY. pr…
Enforced through the FDA through REGISTRATIONS of all parties…
...
Promotes drug studies in children. See how existing drugs wor…
Pure Food and Drug Act
FDA can enforce the standards to drug STRENGTH and PURITY. pr…
Food Drug and Cosmetic Act
Enforced through the FDA through REGISTRATIONS of all parties…
59 terms
Pharmacology - Principles of Pharmacology (1)
pharmacology
medical pharmacology
toxicology
pharmacoepidemiology
__________________________ is the study of *how drugs exert t…
_________________________ is the science of substances used…
______________________ is a branch of pharmacology that *deal…
______________________ is the study of the effects of drugs o…
pharmacology
__________________________ is the study of *how drugs exert t…
medical pharmacology
_________________________ is the science of substances used…
100 terms
Pharmacology 1
Permeation
Ionized
Which drug acidify the urine?
Non-ionized
movement of drug through barriers (intestinal wall, capillary…
Charged= Water soluble = Better exreted
Ammonium chloride (NH4Cl), Vit C.
Uncharged = Non-water soluble = better penetrate the cell mem…
Permeation
movement of drug through barriers (intestinal wall, capillary…
Ionized
Charged= Water soluble = Better exreted
35 terms
Pharmacology-1
shifting DRC to the right
shifting DRC to the left
first pass metabolism
rate limiting step in absorption
increase ED50, less receptors, more drugs necessary, less pot…
decrease ED50, more receptors, less drugs necessary, more pot…
when the drug is metabolized in the liver before it reaches t…
getting across the epithelial barrier
shifting DRC to the right
increase ED50, less receptors, more drugs necessary, less pot…
shifting DRC to the left
decrease ED50, more receptors, less drugs necessary, more pot…
~Pharmacology 1 - Orientation to Pharmacology~
(1) Drug
(1) Pharmacology
(1) Clinical Pharmacology
(1) Therapeutics
Any chemical that can affect living processes.
The study of drugs and their interactions with living systems…
The study of drugs in humans.
The use of drugs to diagnose, prevent, or to treat disease, O…
(1) Drug
Any chemical that can affect living processes.
(1) Pharmacology
The study of drugs and their interactions with living systems…
209 terms
Antibiotic Pharmacology #1, Pharmacology
List all beta-lactam antibiotics.
What features are shared by the beta-l…
What pharmacologic characteristics are…
List all categories of penicillins.
-penicillins ... -cephalosporins... -carbapenems... -aztreonam/monobac…
-chemical structure... -mechanism of action... -pharmacologic chara…
-most are excreted in the urine
-natural penicillins... -extended-spectrum penicillins... -anti-sta…
List all beta-lactam antibiotics.
-penicillins ... -cephalosporins... -carbapenems... -aztreonam/monobac…
What features are shared by the beta-l…
-chemical structure... -mechanism of action... -pharmacologic chara…
169 terms
Pharmacology 1 - Lecture Exam 1
1 kilogram
1 gram
1 milligram
1 kilogram
1000 grams
1000 milligrams
1000 micrograms
2.2 pounds
1 kilogram
1000 grams
1 gram
1000 milligrams
42 terms
Exam 1: Pharmacology
pharmaceutic
pharmacokinetics
3 Major Processes for Drug Absorption…
The second phase, the pharmokinetic ph…
disintegration and dissolution (oral meds only)
absorption- process of drug absorption
Passive Absorption, Active Absorption, and Pinocytosis.
absorption, distribution, metabolism and excretion or elimina…
pharmaceutic
disintegration and dissolution (oral meds only)
pharmacokinetics
absorption- process of drug absorption
25 terms
Pharmacology 1
Three phases of drug interaction include
Pharmacokinetics include the following…
Adverse drug reactions are undesired r…
One ounce is the equivalent of
Pharmaceutic... Pharmacokinetic... Pharmacodynamic
Absorption... Distribution... Biotransformation... Excretion
True
30 mL
Three phases of drug interaction include
Pharmaceutic... Pharmacokinetic... Pharmacodynamic
Pharmacokinetics include the following…
Absorption... Distribution... Biotransformation... Excretion
81 terms
Pharmacology Exam #1
Drug
ADME
Pharmacodynamics
FARAD
Any chemical agent that affects living processes
Absorption, distribution, metabolism, excretion
The study of the mechanism of action of a drug and its biolog…
The Food Animal Residue Avoidance Databank
Drug
Any chemical agent that affects living processes
ADME
Absorption, distribution, metabolism, excretion
20 terms
Pharmacology 1
What is pharmacology?
What is pharmacokinetics?
What is pharmacodynamics?
What is a xenobiotic?
The science of drugs including their chemical properties & th…
The study of how the body absorbs, distributes, metabolises t…
The study of how drugs have their effect on cells, tissues &…
Any foreign chemical substance such as a drug or toxin.
What is pharmacology?
The science of drugs including their chemical properties & th…
What is pharmacokinetics?
The study of how the body absorbs, distributes, metabolises t…
210 terms
Pharmacology Block 1
component of a cell or organism that i…
quantitative relationship
dose or concentration
pharmacological effect
receptor
Receptors largely determine the (?) between dose or concentra…
Receptors largely determine the quantitative relationship bet…
Receptors largely determine the quantitative relationship bet…
component of a cell or organism that i…
receptor
quantitative relationship
Receptors largely determine the (?) between dose or concentra…
34 terms
Pharmacology 1
Pharmacology
Pharmocodynamics
Pharmacokinetics
Pharmacotherapeutics
the study of drugs
the study of the action of drugs on living tissue
The study of the processes of drug absorption, distribution,…
the study of the use of drugs in treating disease
Pharmacology
the study of drugs
Pharmocodynamics
the study of the action of drugs on living tissue
Pharmacology 1
generic name
trade name (brand name)
phases of pharmocokinetics
absorption of lipid soluble drugs
has only 1; assigned by drug council; can help ID class of drug
assigned by company marketing drug; can have many names
absorption, distribution, metabolism, excretion
more readily absorbed than water soluble drugs
generic name
has only 1; assigned by drug council; can help ID class of drug
trade name (brand name)
assigned by company marketing drug; can have many names
62 terms
Pharmacology Unit 1
pharmacology
adverse reaction
allergic reaction
anaphylactic shock
the science or study of drugs and their actions on living org…
an unexpected and undesirable effect caused by a drug
immediate hypersensitive reaction by the immune system; signs…
a severe and rapid and sometimes fatal hypersensitivity react…
pharmacology
the science or study of drugs and their actions on living org…
adverse reaction
an unexpected and undesirable effect caused by a drug
34 terms
Pharmacology 1
PO
Sublingual
IV
IM
Slower absorbance... FPE
No FPE
100% Bioavail.... Instant absorb... No FPE
High Bioavail... Faster absorb... No FPE
PO
Slower absorbance... FPE
Sublingual
No FPE
309 terms
Pharmacology 1
Uptake transporters Intestinal Epithel…
Efflux transporters Intestinal Epithel…
Uptake transporters in excreting organs
Efflux transporters in excreting organs
moves compounds into the blood (aids in drug absorption)
moves compounds back into the GI (limits drug absorption)
moves compounds from the blood to excreting organs (liver & k…
move compounds from excreting organs into bile & urine
Uptake transporters Intestinal Epithel…
moves compounds into the blood (aids in drug absorption)
Efflux transporters Intestinal Epithel…
moves compounds back into the GI (limits drug absorption)
35 terms
Pharmacology 1
Pharmacokinetics
Receptor Interactions
Pharmacodynamics
Absorption
How drugs Absorbs, Distrubtion and excretion
Sites of various tissues to which some drugs bind to exert th…
Explains how drug works and interacts with various receptors,…
-Movement of medications from point of administration into th…
Pharmacokinetics
How drugs Absorbs, Distrubtion and excretion
Receptor Interactions
Sites of various tissues to which some drugs bind to exert th…
61 terms
Pharmacology 1
Ginkgo Biloba (herbal med)
St. John's Wort (herbal med)
Saw Palmetto (herbal med)
Echinacea (herbal med)
treats poor memory and mild dementia
treats depression
treats enlarged prostate
treats the common cold
Ginkgo Biloba (herbal med)
treats poor memory and mild dementia
St. John's Wort (herbal med)
treats depression
Pharmacology 1
In vitro Studies
In vivo studies
Phase 1 of clinical trial
Phase 2 of clinical trial
Understanding the disease and testing molecules in a lab outs…
Pre-clinical stage - includes animal testing
Testing safety with around 50 healthy people
Dosages/efficacy with hundreds of people
In vitro Studies
Understanding the disease and testing molecules in a lab outs…
In vivo studies
Pre-clinical stage - includes animal testing
422 terms
Pharmacology 1
biochemical, physiological effects/mec…
absorption, distribution, metabolism,…
FDA
scheduled drugs only
Pharmacodynamics (definition)
Pharmacokinetics (definition)
what US entity regulates drugs?
when should the DEA number be included in a prescription?
biochemical, physiological effects/mec…
Pharmacodynamics (definition)
absorption, distribution, metabolism,…
Pharmacokinetics (definition)
pharmacology 1
pharmokinetics
site of action
onset of action
drug 1/2 life
impact of the body on a drug
site where drug has a chemical interaction to produce biologi…
length of time drug produces effect on body
time for the drug concentration to decrease to half of the or…
pharmokinetics
impact of the body on a drug
site of action
site where drug has a chemical interaction to produce biologi…
Pharmacology 1
2.5 cm = ? in.
454 g = ? lb
1 kg = ? lb
1lb = ? fl. oz
1 in.
1 lb
2.2 lb
16 fl. Oz. F
2.5 cm = ? in.
1 in.
454 g = ? lb
1 lb
38 terms
Pharmacology Chapter 1
How many drug phases are there?
Requires a carrier such as a protein o…
These are a range or untoward effects…
drugs that produce a response
3 Pharmaceutic phase, Pharmacokinetic phase, pharmacodynamic…
active absorption
adverse reaction
agonists
How many drug phases are there?
3 Pharmaceutic phase, Pharmacokinetic phase, pharmacodynamic…
Requires a carrier such as a protein o…
active absorption
61 terms
Pharmacology 1
Non official resources
Pharmacology
Official Resources
Food, Drug, and Cosmetic Act of 1903
pharmacist, drug insert, printout, Davis Drug Guide
the study of the effects of chemical substances on living tis…
The U.S Pharmacopeia National Formulary
americas first law to regulate drugs; did not address safety…
Non official resources
pharmacist, drug insert, printout, Davis Drug Guide
Pharmacology
the study of the effects of chemical substances on living tis…
Pharmacology #1
Pharmacokinetics is
Pharmaco is
Kinetics is
Pharmacokinetics consists of four steps
What the body does to drugs after they are administered
medicines
movement
absorption, distribution, metabolism, and excretion
Pharmacokinetics is
What the body does to drugs after they are administered
Pharmaco is
medicines
56 terms
Pharmacology 1
Ginkgo Biloba (herbal med)
St. John's Wort (herbal med)
Saw Palmetto (herbal med)
Echinacea (herbal med)
treats poor memory and mild dementia
treats depression
treats enlarged prostate
treats the common cold
Ginkgo Biloba (herbal med)
treats poor memory and mild dementia
St. John's Wort (herbal med)
treats depression
11 terms
pharmacology 1
drug
pharmacology
drug names
pharmacokinetics
Any chemical that affects the physiologic processes of a livi…
Study of drugs and their effects on the body
Chemical, Generic/Non-Proprietary, Trade/Brand/Proprietary
How the body changes drug
drug
Any chemical that affects the physiologic processes of a livi…
pharmacology
Study of drugs and their effects on the body
18 terms
Pharmacology 1
pharmacotherapy
synthetic drugs
semi-synthetic drugs
prototype
drug therapy
standardized in their chemical characteristics, more consiste…
many antibiotics are naturally occurring substances that have…
an individual drug that represents groups of drugs, typically…
pharmacotherapy
drug therapy
synthetic drugs
standardized in their chemical characteristics, more consiste…
102 terms
Pharmacology 1
Over the counter drugs
Advantages of OTD
Disasvantages of OTD
Prescription drugs
Medications that does not need the order of the doctors to ge…
-No health care provider appointment required... -less expensive
-May choose wrong drug... -may not know reactions or interaction…
Drugs require the recipient ontain a written order frim a per…
Over the counter drugs
Medications that does not need the order of the doctors to ge…
Advantages of OTD
-No health care provider appointment required... -less expensive
Ch. 1 Introduction to Pharmacology
adverse effect
agonist
antagonist
chemical name
general term for undesirable and potentially harmful drug eff…
drug that binds to a receptor and activates a physiologic res…
drug that binds to a receptor and interferes with other drugs…
name that defines the chemical composition of a drug
adverse effect
general term for undesirable and potentially harmful drug eff…
agonist
drug that binds to a receptor and activates a physiologic res…
430 terms
Pharmacology 1
Drug
Generic Name
Brand/Trade Name
Antibiotics
any chem that can affect living processes
Company develops and gives it official name (not capitalized)
commercial name (capitalized)... may vary
drugs that treat infections
Drug
any chem that can affect living processes
Generic Name
Company develops and gives it official name (not capitalized)
130 terms
Pharmacology 1-6
name 4 small molecule neurotransmitters
neurotransmitters most commonly involv…
primary neurotransmitters in the auton…
name 4 places where transmission is me…
dopamine... norepinephrine... serotonin... histamine
norepinephrine... acetylcholine... dopamine... serotonin... histamine... GABA
acetylcholine... norepinephrine
1. adrenal medulla... 2. nerve impulses across autonomic ganglia…
name 4 small molecule neurotransmitters
dopamine... norepinephrine... serotonin... histamine
neurotransmitters most commonly involv…
norepinephrine... acetylcholine... dopamine... serotonin... histamine... GABA
131 terms
Pharmacology #1 - Fundamentals of Clinical Pharmacology
Pharmacokinetics = What the ____ does…
4 main concepts of pharmacokinetics
Definition of bioavailability
Parenteral routes of administration
What the BODY does to the DRUG
1) Absorption... 2) Distribution / Redistribution... 3) Transfer /…
Relative amount of drug that reaches systemic circulation
1) Intravascular (IV)... 2) Intramuscular (IM)... 4) Intradermal... 5)…
Pharmacokinetics = What the ____ does…
What the BODY does to the DRUG
4 main concepts of pharmacokinetics
1) Absorption... 2) Distribution / Redistribution... 3) Transfer /…
21 terms
Pharmacology 1
Chemical Name of a drug
Generic Name
Trade Name
Pharmacotherapeutics
describes the drug's chemical composition; know that drugs ha…
Name given by the US Adopted Name Council/ use this and trade…
the drug has a registered trademark; use of the name is restr…
the use of drugs and the clinical indications for drugs to pr…
Chemical Name of a drug
describes the drug's chemical composition; know that drugs ha…
Generic Name
Name given by the US Adopted Name Council/ use this and trade…
Pharmacology 1
Additive effects
Adverse drug event
Adverse drug reaction
Adverse effects
Drug interactions in which the effect of a combination of two…
Any undesirable occurrence related to administering or failin…
Any unexpected, unintended, undesired, or excessive response…
A general term for any undesirable effects that are a direct…
Additive effects
Drug interactions in which the effect of a combination of two…
Adverse drug event
Any undesirable occurrence related to administering or failin…
42 terms
Pharmacology-Chapter 1
adverse effect
agonist
antagonist
chemical name
general term for undesirable and potentially harmful drug eff…
drug that binds to a receptor and activates a physiologic res…
drug that binds to a receptor and interferes with other drugs…
name that defines the chemical composition of a drug.
adverse effect
general term for undesirable and potentially harmful drug eff…
agonist
drug that binds to a receptor and activates a physiologic res…
183 terms
Pharmacology 1
Pharmacokinetic Principles
Absorption
Distribution
Major forms of Elimination
-Absorption, Distribution, Elimination
- method of drug administration... - dosage form of drug... - passa…
- From plasma to to specific and non specific tissue ... - prote…
metabolism in liver and excretion in kidney-
Pharmacokinetic Principles
-Absorption, Distribution, Elimination
Absorption
- method of drug administration... - dosage form of drug... - passa…
pharmacology 1
The word pharmacology was first used in
Modern Pharmacology began in the
20th Century to Present
Pharmacology is the study of ____... and…
published literature in 1693 by Samuel Dale
early 1800s... • Chemists isolated pharmacological substances f…
• Drugs are synthesized in laboratories... • Drugs tested for re…
• Pharmacology is the study of drugs... - includes how drugs are…
The word pharmacology was first used in
published literature in 1693 by Samuel Dale
Modern Pharmacology began in the
early 1800s... • Chemists isolated pharmacological substances f…
Pharmacology 1
Three things physicians need to know b…
Drug administration-
Pharmokinetics-
Pharmicodynamics-
1. Drug administration... 2. Pharmokinetics... 3.Pharmicodynamics
How to give it.... Method by which it is available
How long the effects last.... Absorption, Distribution, metaboli…
How does the drug molecule cause its effect within the body.
Three things physicians need to know b…
1. Drug administration... 2. Pharmokinetics... 3.Pharmicodynamics
Drug administration-
How to give it.... Method by which it is available
71 terms
Pharmacology 1
Golytely
Lactulose
Glycerin
Bisacodyl
Hyperosmotic Laxative
Hyperosmotic Laxative
Hyperosmotic Laxative
Stimulant Laxative
Golytely
Hyperosmotic Laxative
Lactulose
Hyperosmotic Laxative
68 terms
Pharmacology 1
Summary sheet
History and physical examination
Problem list
Physicians orders
Basic information about the patient
A total history and examination are complete by the physician
Problem list contains all the symptoms,signs,problems and dia…
All procedures and treatments ate ordered on the physicians o…
Summary sheet
Basic information about the patient
History and physical examination
A total history and examination are complete by the physician
63 terms
pharmacology 1
ideal drug
A. safety
ed 50
ld 50
an ideal drug is safe, with no harmful effects, even at high…
). Baseline assessments, check related labs, identify any rea…
effective dose. average dose 50 %
lethal dose/ harm/kill subjects
ideal drug
an ideal drug is safe, with no harmful effects, even at high…
A. safety
). Baseline assessments, check related labs, identify any rea…
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