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Study sets matching "pulm"

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Study sets matching "pulm"

70 terms
Pulm
Sternum parts and articulations
How many ribs
True ribs
False ribs
Manubrium ... Body... Xiphoid process... Manubrium + clavicle > clavi…
12
1-7, attach to sternum by costal cartilage
8-10, attach by cartilage to cartilage of above rib (not to s…
Sternum parts and articulations
Manubrium ... Body... Xiphoid process... Manubrium + clavicle > clavi…
How many ribs
12
100 terms
Pulm
REVIEW: To which lymph nodes would can…
REVIEW: what is the classic triad of s…
REVIEW: Which lysosomal storage diseas…
What structures traverse the diaphragm…
Stomach = Celiac nodes... Duodenum, jejunum = Superior mesenteri…
Charcot's classic Triad is a SIN:... Scanning Speech... Intention t…
Accumulation of GM2 ganglioside = Tay-Sachs disease... Associat…
I 8 10 eggs at 12... T8 = IVC... T10 = Esophagus, vagus nerve... T12…
REVIEW: To which lymph nodes would can…
Stomach = Celiac nodes... Duodenum, jejunum = Superior mesenteri…
REVIEW: what is the classic triad of s…
Charcot's classic Triad is a SIN:... Scanning Speech... Intention t…
9 terms
Pulm
hammon's crunch
Hamptom's hump, pulmonary embolus
Kerley B lines
mucoid
__ is a systolic crunching sound associated with mediastinal…
__ is a wedge shaped consolidation at the lung periphery on a…
__ are horizontal opaque lines extending to the pulmonary per…
__ sputum is translucent, white, or gray
hammon's crunch
__ is a systolic crunching sound associated with mediastinal…
Hamptom's hump, pulmonary embolus
__ is a wedge shaped consolidation at the lung periphery on a…
914 terms
Pulm
Lecture 1: embryology anatomy normal rad
which of the germ layers does the lung…
Stages of Lung Development
describe the embryological development…
...
endoderm (gut lining)
1. embryonic period... 2. pesudoglandular stage... 3. canalicular s…
from the gut tube comes the resp diverticulum.... at 28 days the…
Lecture 1: embryology anatomy normal rad
...
which of the germ layers does the lung…
endoderm (gut lining)
177 terms
Pulm
conducting zone:
respiratory zone:
blood flow (l/min.):
average systemic pressures:
the part of the respiratory system made up of the nose, phary…
the part of the respiratory system found deep inside the lung…
5 l/min.
systolic: 120 mmHg... diastolic: 80 mmHg... MAP: 95 mmHg... avg. cap.…
conducting zone:
the part of the respiratory system made up of the nose, phary…
respiratory zone:
the part of the respiratory system found deep inside the lung…
44 terms
Pulm
Total lung volumes
Atelectasis
Auscultation
Rales
Vital Capacity - VC = IRV + ERV + TV
Shrunken/airless part of the lung. Acute or chronic. Often as…
Listening to breath sounds using stethoscope. Normal - vesicu…
Crackles. Discontinuous sounds heard during inspiration. Air…
Total lung volumes
Vital Capacity - VC = IRV + ERV + TV
Atelectasis
Shrunken/airless part of the lung. Acute or chronic. Often as…
57 terms
pulm
which lobe of the lung is most likely…
branches of the right main bronchus
branches of the left main bronchus
3 functional zones of the lung
Right lower
upper, middle, lower
upper, lower (upper will split into upper and lingular)
conduction, transitional, respiratory
which lobe of the lung is most likely…
Right lower
branches of the right main bronchus
upper, middle, lower
227 terms
Pulm
Hyperinflatinon: Exercise induced asthma
Inhaler instructions
Risk factor for COPD
Small airways disease
Antitrypsin deficiency
Smoking --> activation of epithelial cells --> fibroblasts --…
Hyperinflatinon: Exercise induced asthma
Inhaler instructions
144 terms
Pulm
This much improvement in FEV1 in spiro…
bronchial challenge test is sensitive…
abnormal Pulse oximetry is < ?%
TLC, RV=residual volume, ... vital cap…
> 12 % and at least 200 cc
methacholine, Histamin, Mannitol... 20 %... Cold air and exercise 1…
< 95 % or >5 % reduction w exersion
FEv1/Fvc <70 %... then look at FEV1 ... Moderately reduced:50-80 %…
This much improvement in FEV1 in spiro…
> 12 % and at least 200 cc
bronchial challenge test is sensitive…
methacholine, Histamin, Mannitol... 20 %... Cold air and exercise 1…
87 terms
PULM
Nicotine MOA
Varenicline (Champix) - MOA
Varenicline (Champix) - Method and Sid…
Buproprion - MOA
1) Dopamine (reward pathway) release after binding alpha4beta…
Partial Agonist - MORE efficacious than the others... - Decrease…
Method: Start 1 week before so stable w/ side effects... 1) Naus…
Reuptake Inhibitor... - Inhibits reuptake of DA, NE, therefore i…
Nicotine MOA
1) Dopamine (reward pathway) release after binding alpha4beta…
Varenicline (Champix) - MOA
Partial Agonist - MORE efficacious than the others... - Decrease…
82 terms
Pulm
how are the terminal bronchioles arran…
conducting zone
respiratory zone
type I cell (pneumocyte)
parallel ... airway resistance goes down as you go further down…
warm and humidify air... dead space
gas exchange... macs for immune response
squamous... thin for gas diffusion
how are the terminal bronchioles arran…
parallel ... airway resistance goes down as you go further down…
conducting zone
warm and humidify air... dead space
50 terms
Pulm
Main respiratory elements include
Upper airway
lower airway
Pulmonary ventilation
1) Chest wall... 2) Airways (upper & lower)... 3) Alveolar-capillar…
Made up of nasal turbinates, pharynx, hypopharynx filter & h…
Everything distal to epiglottis alveoli... Alveolar-capillary u…
inflow and outflow of air between atmosphere and lung alveoli
Main respiratory elements include
1) Chest wall... 2) Airways (upper & lower)... 3) Alveolar-capillar…
Upper airway
Made up of nasal turbinates, pharynx, hypopharynx filter & h…
20 terms
Pulm
Emphysema
Chronic Bronchitis
Asthma
Bronchiectasis
- increased compliance ... resonance to percussion, diminished b…
productive cough for at least three months per year over at l…
reversilbe obstructive disease characterized by hyperreactive…
irreversible dilation of airways caused by inflammatory destr…
Emphysema
- increased compliance ... resonance to percussion, diminished b…
Chronic Bronchitis
productive cough for at least three months per year over at l…
19 terms
Pulm
Bronchiectasis
Obstructive lung disease
Proven Interventions for COPD
Restrictive
Cycles of infection and inflammation in bronchi leading to fi…
A asthma ... B bronchiectasis ... C copd/cf... T tracheal or bronchial…
O2 titrated for greater than 15 hours a day at 90% and smokin…
A alveolar (edema hemorrhage pus )... Interstitial (sarcoidosis,…
Bronchiectasis
Cycles of infection and inflammation in bronchi leading to fi…
Obstructive lung disease
A asthma ... B bronchiectasis ... C copd/cf... T tracheal or bronchial…
185 terms
Pulm
Examples of Lung Diagnoses
Examples of Vascular Diagnoses
Examples of Airway Diagnoses
Examples of Mechanical Diagnoses
Interstitial Lung Disease... Pulmonary Nodules... Pneumonia... Atelect…
Pulmonary Hypertension... Pulmonary Embolism
Asthma ... Emphysema... Chronic Bronchitis
Neuromuscular Disease... Pleural Pathology
Examples of Lung Diagnoses
Interstitial Lung Disease... Pulmonary Nodules... Pneumonia... Atelect…
Examples of Vascular Diagnoses
Pulmonary Hypertension... Pulmonary Embolism
393 terms
Pulm
4 differences between large and small…
smallest airways without alveoli
respiratory tree starting with nose
respiratory zone composed of
Bronchi --> Bronchioles (beginning of TERMINAL)... -Epithelium:…
terminal bronchioles
nose... larynx... trachea... R/L bronchi... lobar bronchi... segmental bronc…
respiratory bronchioles and alveolar ducts
4 differences between large and small…
Bronchi --> Bronchioles (beginning of TERMINAL)... -Epithelium:…
smallest airways without alveoli
terminal bronchioles
38 terms
Pulm
Physiologic dead space
Alveolar ventilation
Collapsing pressure
Type I vs Type II pneumocytes
Physiologic dead space= Tidal Volume ([PaCO2-PECO2]/*Pa…
VA=(VT-VD)*RR... volume of gas that reaches alveoli per unit ti…
Collapsing P = 2 (Surface Tension) / Radius... law of Laplace:…
Type I: squamous, thin for gas diffusion... Type 2: surfactant (…
Physiologic dead space
Physiologic dead space= Tidal Volume ([PaCO2-PECO2]/*Pa…
Alveolar ventilation
VA=(VT-VD)*RR... volume of gas that reaches alveoli per unit ti…
251 terms
pulm
asthma: PFT improvement seen w broncho…
obstruction w normal vs dec DLCO
causes of airway obstruction in asthma
PFT interpretation
FEV1, inc 12% or 200mL
asthma, chronic bronchitis, bronchiectasis vs emphysema
1) smooth muscle - bronchoconstriction; 2) inflamed airway, 3…
1) FEV1/FVC: low (<70-80%) = obstruction --> check reversibil…
asthma: PFT improvement seen w broncho…
FEV1, inc 12% or 200mL
obstruction w normal vs dec DLCO
asthma, chronic bronchitis, bronchiectasis vs emphysema
58 terms
Pulm
Differential for Hypoventilation
Which cause of hypoventilation will ha…
Differential for Hyperventilation
Drivers of Respiration
Brain - congenital central hypoventilation, drugs, hypothyroi…
A
Physiologic Cause: hypoxia, acidosis, irritants, CHF, DKA ... No…
medullary pacemaker... hypercapnia (high CO2)... Hypoxia... Mechanorec…
Differential for Hypoventilation
Brain - congenital central hypoventilation, drugs, hypothyroi…
Which cause of hypoventilation will ha…
A
78 terms
Pulm
Drug of choice to prevent altitude sic…
Best tidal volume for mechanical venti…
Genetic disease suggested by this radi…
Reduces risk of air embolism during ce…
Acetazolamide
6 mL/kg ideal body weight
Alpha-1-antitrypsin deficiency
Trendelenburg position or Valsalva (either)
Drug of choice to prevent altitude sic…
Acetazolamide
Best tidal volume for mechanical venti…
6 mL/kg ideal body weight
114 terms
Pulm
what 2 meds can worsen / trigger asthma
who might outgrown asthma ... who might n…
is asthma mortality on the rise?
what do you need to get in a kid with…
beta blockers... ASA!
mild - 2/3rds outgrow by adults... severe only a 1/3 rd outgrow
YES
regular PFTs in office... (peak flow = only management at home)
what 2 meds can worsen / trigger asthma
beta blockers... ASA!
who might outgrown asthma ... who might n…
mild - 2/3rds outgrow by adults... severe only a 1/3 rd outgrow
185 terms
Pulm
What diseases are categorized as obstr…
What is definition of obstructive lung…
What airways are affected in asthma?
What airways are affected in chronic b…
COPD: chronic bronchitis, emphysema... -asthma... -bronchiectasis
-chronic inflammatory dx of airways w/ obstruction of airflow
-bronchi & bronchioles
-bronchi & bronchioles
What diseases are categorized as obstr…
COPD: chronic bronchitis, emphysema... -asthma... -bronchiectasis
What is definition of obstructive lung…
-chronic inflammatory dx of airways w/ obstruction of airflow
60 terms
Pulm
Wells criteria
Do long distance flights count as immo…
Pleural plaques/calcifications on ches…
PCWP is an indicator of
...
Nope! They are a risk factor... Immobilization is bedridden for…
Asbestosis
Left atrial pressure
Wells criteria
...
Do long distance flights count as immo…
Nope! They are a risk factor... Immobilization is bedridden for…
42 terms
Pulm
what lung disease is associated with r…
IPF
Honeycombing
reduced 6 minute walk
IPF
clubbing and velcro crackles
IPF ... DX biopsy
IPF ... older men
what lung disease is associated with r…
IPF
IPF
clubbing and velcro crackles
46 terms
Pulm
acute phase reactants
LTB4
EPO
fibrinogen (acute phase reactant)
fibrinogen, ferritin, serum amyloid A, serum amyloid P, compl…
metabolite of arachadonic acid; stimulates neutrophil migrati…
produced by peritubular cells of kidney in response to hypoxia
high levels of this in the circulation increase the ESR, a no…
acute phase reactants
fibrinogen, ferritin, serum amyloid A, serum amyloid P, compl…
LTB4
metabolite of arachadonic acid; stimulates neutrophil migrati…
114 terms
Pulm
what 2 meds can worsen / trigger asthma
who might outgrown asthma ... who might n…
is asthma mortality on the rise?
what do you need to get in a kid with…
beta blockers... ASA!
mild - 2/3rds outgrow by adults... severe only a 1/3 rd outgrow
YES
regular PFTs in office... (peak flow = only management at home)
what 2 meds can worsen / trigger asthma
beta blockers... ASA!
who might outgrown asthma ... who might n…
mild - 2/3rds outgrow by adults... severe only a 1/3 rd outgrow
149 terms
Pulm
What're 3 components of work of breath…
Inspiration is (active/inactive)......…
Equations for resistance
Which system has more resistance in th…
1) pressure to overcome compliance of chest wall... 2) pressur…
Inspiration is active while expiration is inactive (due to el…
R = ( P(A) - P(ao) )/flow... --A = alveolar... --ao = airway openin…
Conducting zone has more resistance because of lack of *lamin…
What're 3 components of work of breath…
1) pressure to overcome compliance of chest wall... 2) pressur…
Inspiration is (active/inactive)......…
Inspiration is active while expiration is inactive (due to el…
67 terms
Pulm
Nitric Oxide (NO)
Acetylcholine
Reserpine
Guanadrel
vasodilator (relaxes vascular and other smooth muscle); activ…
MOA: Endogenous muscarinic & nicotinic receptor agonist; *can…
sympathetic nerve terminal blocker; blocks VMAT and depletes…
sympathetic nerve terminal blocker; guanethidine-like drug av…
Nitric Oxide (NO)
vasodilator (relaxes vascular and other smooth muscle); activ…
Acetylcholine
MOA: Endogenous muscarinic & nicotinic receptor agonist; *can…
90 terms
pulm
What are the other muscles (besides di…
What are the other muscles used for ex…
What's the difference between Type 1 a…
How do you determine fetal lung maturi…
Sternocleidomastoids, external intercostals, scalene muscles
Transversus abdominis, rectus abdominis, internal and externa…
Type 1 = majority of lung cells (simple squamous epithelial c…
Lecithin: Sphingomyelin Ratio > 2 in amniotic fluid
What are the other muscles (besides di…
Sternocleidomastoids, external intercostals, scalene muscles
What are the other muscles used for ex…
Transversus abdominis, rectus abdominis, internal and externa…
125 terms
Pulm
Upper respiratory tract
Lower respiratory tract
Lower respiratory tract consists of
Respiratory mucosa
Passageways that conducts air between atmosphere and lungs
Where gas exchange takes place
trachea, bronchial trees, lungs
Pseudo-stratified ciliated columnar epithelium
Upper respiratory tract
Passageways that conducts air between atmosphere and lungs
Lower respiratory tract
Where gas exchange takes place
112 terms
*Pulm
Recurrent sinopulmonary (strep & hemop…
Catarrhal (1-2wk) - mild cough, rhinit…
Bronchiectasis, recurrenent pneumonia,…
<2yo... RSV... Nasak congestion/dc & cough... W…
IgA deficiency... Anaphylactic transfusion rxn
Pertussis... TX: macrolides (-thromycin)
CF (cystic fibrosis)... F508 mutation... -Meconium ileus (contra…
Bronchiolitis... Prevention: palivizumab in premi, lung or hear…
Recurrent sinopulmonary (strep & hemop…
IgA deficiency... Anaphylactic transfusion rxn
Catarrhal (1-2wk) - mild cough, rhinit…
Pertussis... TX: macrolides (-thromycin)
19 terms
pulm
what type of sequestration is assoc c…
what type of cpam is assoc c inc r/o l…
what type of cpam has the worst prog
which NSIP is worse
extralobar
1; otherwise good prog
2 (other than 0 which is nonviable); assoc c other abs
fibrosing; also can progress to UIP
what type of sequestration is assoc c…
extralobar
what type of cpam is assoc c inc r/o l…
1; otherwise good prog
36 terms
pulm
At 1min, newborn: HR 96, slow, irreg b…
Apgar score - chart
32yo with chronic asthma, to ED w/ acu…
42yoF, eval of asthma sxs. Reports awa…
6: Apgar point calc:... HR (1)... respiratory effort (1)... muscle ton…
Prepare to intubate: ... *Pt is in Status asthmaticus: must intu…
Low-potency ICS (or medium)... PLUS... long-acting β-agonist (LABA)…
At 1min, newborn: HR 96, slow, irreg b…
6: Apgar point calc:... HR (1)... respiratory effort (1)... muscle ton…
Apgar score - chart
233 terms
Pulm
which lung has 3 lobes?
what 3 layers are passed going from br…
from what embryonic layer do the lungs…
from what embryonic layer does the pul…
right lung
inner mucosal surfacesmooth musclecartilage connective tissue
Endoderm
mesenchyme
which lung has 3 lobes?
right lung
what 3 layers are passed going from br…
inner mucosal surfacesmooth musclecartilage connective tissue
97 terms
Pulm
- Bullous myringitis (blistering of ty…
The primary cause of mortality from in…
Community Acquired Pneumonia... Typical…
Hospital Acquired Pneumonia ... Tx?
Mycoplasma... Tx: Macrolide
Pneumonia ... - Inflammation in the alveoli or interstitium of t…
Typical: Strep pneumo, H. influenzae, M. catarrhalis... Tx: Macr…
Staph aureus... Pseudomonas aeruginosa ... - Bactrim
- Bullous myringitis (blistering of ty…
Mycoplasma... Tx: Macrolide
The primary cause of mortality from in…
Pneumonia ... - Inflammation in the alveoli or interstitium of t…
84 terms
PULM
3rd leading cause of death
nicotine moa causing trouble
dx copd
causes of cold
copd/smoking- destructive cuase of smoking
nicotine= potent vasoconstrictor, common cause of cad... circula…
fev1/fvc postbronchodilator of <.7... sputum >3 mo of the yr for…
1= smoking... small percentage= a-antitrypsin def
3rd leading cause of death
copd/smoking- destructive cuase of smoking
nicotine moa causing trouble
nicotine= potent vasoconstrictor, common cause of cad... circula…
33 terms
Pulm
What organism species is most indicate…
what condition should be considered fo…
what type of tumor is associated with…
where is primary TB and secondary Tb (…
bacteroides species (anaerobic bacteria)
alpha-1-antitrypsin deficiency causing the destruction of alv…
carcinoid tumor
- primary is found in the base... - secondary in apex
What organism species is most indicate…
bacteroides species (anaerobic bacteria)
what condition should be considered fo…
alpha-1-antitrypsin deficiency causing the destruction of alv…
84 terms
Pulm
what are the 4 types of pneumonia
this is diagnosed outside the hospital…
describe community acquired pneumonia
this pneumonia occurs in non-hospitali…
-community acquired pneumonia... -healthcare associate pneumonia…
community acquired pneumonia
infection of the lung parenchyma that causes consolidation an…
healthcare associated pneumonia
what are the 4 types of pneumonia
-community acquired pneumonia... -healthcare associate pneumonia…
this is diagnosed outside the hospital…
community acquired pneumonia
28 terms
Pulm
Terbutaline
Albuterol
Salmeterol
Formoterol
- Commonly used B2-agonist for COPD and asthma... - *Relax bro…
- MOST commonly used B2-agonist for COPD and asthma - *shor…
- Long acting B2-agonist for COPD and asthma... - *Relax bronc…
- Long acting B2-agonist for COPD and asthma... - *Relax bronc…
Terbutaline
- Commonly used B2-agonist for COPD and asthma... - *Relax bro…
Albuterol
- MOST commonly used B2-agonist for COPD and asthma - *shor…
147 terms
Pulm
what symptoms does asthma present with?
whats the allergic triad?
physical exam of asthma?
sign to intubate during asthma exacerb…
dyspnea and wheezing in younger patients
asthma, nasal polyps, ASA/NSAID insensitivity
paradoxical pulse, decreased breath sounds/less air entry/sil…
resp muscle fatigue causing resp acidosis
what symptoms does asthma present with?
dyspnea and wheezing in younger patients
whats the allergic triad?
asthma, nasal polyps, ASA/NSAID insensitivity
19 terms
Pulm
how does lateral decub position affect…
what is nl wedge pressure what is elev…
What causes R shift of O2 curve
What is dead space? What are all the t…
increases vq mismatch
nl <18 greater 18 in CHF and greater than 30 in pulm edema
metabolic acidosis/lactic acidosis/ rhabdomyolysis/renal fail…
Ventilation but no perfusion ie PE/ asthma/ COPD/ obesity/ CF
how does lateral decub position affect…
increases vq mismatch
what is nl wedge pressure what is elev…
nl <18 greater 18 in CHF and greater than 30 in pulm edema
198 terms
Pulm
Abrasion
Acute
Anterior
Benign
Scrape of the skin due to something abrasive
New, usually of rapid onset and concern. Opposite of chronic.
Located towards the front of the body
Normal, of no danger to health
Abrasion
Scrape of the skin due to something abrasive
Acute
New, usually of rapid onset and concern. Opposite of chronic.
11 terms
PULM:
Pulm Sequestration DEF
Pulm Sequestration CLIN
Congenital Adenomatoid Malformation (C…
Congenital Adenomatoid Malformation (C…
non-funxnl tissue isolated from NL lung, but fed by systemic…
recurrent pulm infxns, LLL most freq, hyPERlucency
overgrowth of pulm tissue in region of end bronchioles
recurrent pulm infxns, hyPOlucency, may shift heart
Pulm Sequestration DEF
non-funxnl tissue isolated from NL lung, but fed by systemic…
Pulm Sequestration CLIN
recurrent pulm infxns, LLL most freq, hyPERlucency
61 terms
PULM
Signs and Symptoms of Pulmonary Disease
Dyspnea is due to
Cough is due to
coughing attempts to clear the
Dyspnea - subjective sensation of uncomfortable breathing, fe…
Airway obstruction ... Greater force needed to provide adequate…
Inflammation of lung tissue... Increased secretion in response…
lower respiratory passages by abrupt and forceful expulsion o…
Signs and Symptoms of Pulmonary Disease
Dyspnea - subjective sensation of uncomfortable breathing, fe…
Dyspnea is due to
Airway obstruction ... Greater force needed to provide adequate…
21 terms
Pulm
COPD azithromycin
asthma
thrombolytics use in PE
massive PE
2+ exacerbations per year... reduces hospitalizations, time to n…
1. SABA... 2. inhaled steroid
SBP < 90 or drop in SBP < 40... heparin gtt after tPA... no time cu…
hemodynamic compromise
COPD azithromycin
2+ exacerbations per year... reduces hospitalizations, time to n…
asthma
1. SABA... 2. inhaled steroid
201 terms
Pulm
OUTPATIENT CAP EMPIRIC THERAPY... No como…
OUTPATIENT CAP EMPIRIC THERAPY... Comorbi…
INPATIENT CAP EMPIRIC THERAPY
NON RESOLVING PNEUMONIA
Azithromycin, clarithromycin, doxycycline x 5 days
Fluoroquinolone x 5 days... Amoxicillin or Amoxicillin-Clavulana…
Fluoroquinolone OR beta lactam plus macrolide OR Tygecycline…
CT chest... Pleural effusion, lung abscess, airway obstruction,…
OUTPATIENT CAP EMPIRIC THERAPY... No como…
Azithromycin, clarithromycin, doxycycline x 5 days
OUTPATIENT CAP EMPIRIC THERAPY... Comorbi…
Fluoroquinolone x 5 days... Amoxicillin or Amoxicillin-Clavulana…
64 terms
Pulm
intermittent asthma
mild asthma
moderate asthma
severe asthma
Sx < 2 days per week... Meds < 2 days per week... Wake up < 2 night…
Sx > 2 days per week... Meds > 2 days per week... Wake up 3-4 X per…
Sx daily... Meds daily... Wake up > 1 night per week
Sx throughout the day... Meds throughout the day... Wake up nightly
intermittent asthma
Sx < 2 days per week... Meds < 2 days per week... Wake up < 2 night…
mild asthma
Sx > 2 days per week... Meds > 2 days per week... Wake up 3-4 X per…
8 terms
Pulm
Systemic Steroids
Anti-IgE Therapy
Methylxanthines
Leukotriene modifiers
Step 4 or 5; Omalizumab... Anti-inflammation... Slow-onset: impro…
-Binds free IgE and inhibits it from binding Mast cells→decre…
Step 4 and up... First line therapy for over 50 years... Reduced…
-Step 2, 3, 4... Reduce bronchospastic response to allergens, c…
Systemic Steroids
Step 4 or 5; Omalizumab... Anti-inflammation... Slow-onset: impro…
Anti-IgE Therapy
-Binds free IgE and inhibits it from binding Mast cells→decre…
17 terms
pulm
Ghon complex' ... prominent hilar lymphad…
shortness of breath, fever, weight los…
AAT deficiency
Mycobacterium tuberculosis primary, TB infection. - periphera…
Sarcoidosis is typified by non-caseating granulomas. However,…
leads to lack of an anti-protease, which leads to development…
Ghon complex' ... prominent hilar lymphad…
Mycobacterium tuberculosis primary, TB infection. - periphera…
shortness of breath, fever, weight los…
Sarcoidosis is typified by non-caseating granulomas. However,…
8 terms
Pulm
Bronchial wall in chronic bronchitis
PaCO2 & PaO2 in chronic bronchitis
Findings in A1AT deficiency
Spiral-shaped mucus plugs
Reid index: >50%; normal <40%
PaCO2 incr, PaO2 decr
Liver damage (accumulates in ER of hepatocytes) (cirrhosis w/…
Curschmann spirals (Asthma)
Bronchial wall in chronic bronchitis
Reid index: >50%; normal <40%
PaCO2 & PaO2 in chronic bronchitis
PaCO2 incr, PaO2 decr
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