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Study sets matching "topical agents glaucoma all"

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Study sets matching "topical agents glaucoma all"

9 terms
Drug Cards: Topical Glaucoma Agents
Bimatoprost
Bimatoprost Dose
Bimatoprost Indications
Bimatoprost Adverse Effects
Lumigan... Latisse
1 gtt in affected eye(s) QPM
Reduction of elevated intraocular pressure in patients with o…
Common: conjunctival hyperemia, growth of eyelashes, ocular p…
Bimatoprost
Lumigan... Latisse
Bimatoprost Dose
1 gtt in affected eye(s) QPM
17 terms
Brand/Class - Topical Agents
Alphagan P
Anusol-HC... Proctosol-HC
Bactroban
Cosopt
Glaucoma agent
Topical corticosteroid
Topical antibiotic
Glaucoma agent
Alphagan P
Glaucoma agent
Anusol-HC... Proctosol-HC
Topical corticosteroid
17 terms
Generic/Class - Topical Agents
Bimatoprost
Brimonidine (tartrate)
Clobetasol (propionate)
Clotrimazole and Betamethasone (diprop…
Glaucoma agent
Glaucoma agent
Steroidal anti-inflammatory
Topical antifungal
Bimatoprost
Glaucoma agent
Brimonidine (tartrate)
Glaucoma agent
8 terms
9. *Ophthalmic Agents for Glaucoma
Latanoprost
Dorzolamide
Brimonidine
Timolol
Chronic Glaucoma (DOC), Fuller eyelashes... Prostaglandin:... Topi…
Glaucoma (CI: sulfa-drug sensitivity)... Carbonic Anhydrase Inh…
Glaucoma (usually adjunct)... Agonist: α2... Topical ... ↓secretion... M…
Chronic Glaucoma (DOC) (commonly)... Antagonist: β-nonselective…
Latanoprost
Chronic Glaucoma (DOC), Fuller eyelashes... Prostaglandin:... Topi…
Dorzolamide
Glaucoma (CI: sulfa-drug sensitivity)... Carbonic Anhydrase Inh…
9 terms
Topical Class
Hydrocortisone (rectal)
Proctosol-HC®
Anusol-HC®
Latanoprost
Topical corticosteroid Topical
Topical corticosteroid Topical
Topical corticosteroid Topical
Glaucoma agent Topical
Hydrocortisone (rectal)
Topical corticosteroid Topical
Proctosol-HC®
Topical corticosteroid Topical
31 terms
Glaucoma
lower than 50... african american... monocul…
5db
3 IOP... 2 VF... gonio ... pachymetry ... evalate…
No glauc... high myope... -rim okay, slopoing
when to lower target pressure and additional 10%?
20% loss in NFL is equaibalent to what dB field loss?
what must you get before starting glauc tx?
Glauc?
lower than 50... african american... monocul…
when to lower target pressure and additional 10%?
5db
20% loss in NFL is equaibalent to what dB field loss?
73 terms
Glaucoma
Definition of Glaucoma?
Which of the following is not a cause…
T/F. With glaucoma, peripheral vision…
Open Angle Glaucoma or (POAG) generall…
-a group of disorders characterized by damage to the optic ne…
(B). Intraocular pressure associated with Glaucoma can be cau…
True.
both. (bilateral). Generally a chronic illness.
Definition of Glaucoma?
-a group of disorders characterized by damage to the optic ne…
Which of the following is not a cause…
(B). Intraocular pressure associated with Glaucoma can be cau…
31 terms
Glaucoma
Aqueous Humor
Primary Open Angle Glaucoma
Mechanism of Primary Open Angle Glaucoma
Risk Factors for Primary Open Angle Gl…
Aqueous humor is clear fluid, produced by ciliary body at a r…
60% of all glaucomas... • A.O.A. definition "a group of ocular d…
Mechanical resistance to outflow through trabecular meshwork…
-Increased IOP *... • Age (>60 years)... • African-American (3-6X r…
Aqueous Humor
Aqueous humor is clear fluid, produced by ciliary body at a r…
Primary Open Angle Glaucoma
60% of all glaucomas... • A.O.A. definition "a group of ocular d…
36 terms
Glaucoma and Glaucoma Pharmacology
Formation and Drainage of Aqueous Humor
What is meant by the "angle" in Open a…
Primary Open-Angle Glaucoma
What is the normal range for Intraocul…
*... *... *... *... *... *... *... *
The "angle" refers to the junction of cornea and iris, where…
*most common type of glaucoma (90%)... *More common in African A…
...
Formation and Drainage of Aqueous Humor
*... *... *... *... *... *... *... *
What is meant by the "angle" in Open a…
The "angle" refers to the junction of cornea and iris, where…
69 terms
Glaucoma Y modefy
lower than 50... african american... monocul…
program to use... Humphrey:
full threshold (18 min /eye)
bracketing the threshold
when to lower target pressure and additional 10%?
for glaucoma: 30-2/24-2... macula" 10-2... low vision: with size V
mapped every point, mosre sensitive... disad: prone fatigue and…
4-4-2... start from dimmer then increase intensive 4dB each time…
lower than 50... african american... monocul…
when to lower target pressure and additional 10%?
program to use... Humphrey:
for glaucoma: 30-2/24-2... macula" 10-2... low vision: with size V
12 terms
Glaucoma
Glaucoma
Pathopysiology
Risk Factors
primary open-angle glaucoma (POAG)
is a group of disorders characterized by increased IOP and th…
A proper balance between the rate of aqueous production (refe…
High intraocular pressure... age... african american... family history…
most common type of glaucoma the outflow of aqueous humor is…
Glaucoma
is a group of disorders characterized by increased IOP and th…
Pathopysiology
A proper balance between the rate of aqueous production (refe…
34 terms
Ophtho 2: Glaucoma
Gold standard for measuring IOP
Normal IOP
Steps to use a Goldmann
Does Goldmann touch the eye?
Goldmann
10-21mmHG
Clean instrument, instill anesthetic and flourescein, positio…
No, only touches tears
Gold standard for measuring IOP
Goldmann
Normal IOP
10-21mmHG
24 terms
Glaucoma
Open- angle glaucoma
Open- angle glaucoma
Open- angle glaucoma
Open- angle glaucoma
the drainage canals in the eyes become clogged gradually over…
Most common
Slow onset
Painless and causes no early symptoms
Open- angle glaucoma
the drainage canals in the eyes become clogged gradually over…
Open- angle glaucoma
Most common
104 terms
Glaucoma
POAG
IOP
1 Cause of ________ Worldwide
Progressive __________ optic nerve dam…
Primary Open Angle Glaucoma
Intraocular Pressure
Blindness
irreversible
POAG
Primary Open Angle Glaucoma
IOP
Intraocular Pressure
30 terms
Glaucoma: Pharmacology of Eye and Treatment
Drug list
Glaucoma is characterized by
Optical hypertension
very high intraocular pressure (IOP)
changes in the shape and size of the optic disk and defects i…
considered a clear risk factor for development of glaucoma
will cause irreversible damage via induced ischemia in the op…
Drug list
Glaucoma is characterized by
changes in the shape and size of the optic disk and defects i…
82 terms
GLAUCOMA: Secondary Glaucoma
**Clinical pearl**... does every pigmen…
**Clinical pearl**... is pigmentary gla…
**Clinical pearl**... which type is lik…
**Clinical pearl**... blurred vision wh…
NO, not every pigment dispersion patient develops glaucoma... *…
No, pigmentary dispersion is different in BLACK patients.... **T…
...
pigment release accumulating in the TM= impeding aqueous flow…
**Clinical pearl**... does every pigmen…
NO, not every pigment dispersion patient develops glaucoma... *…
**Clinical pearl**... is pigmentary gla…
No, pigmentary dispersion is different in BLACK patients.... **T…
18 terms
Anti-glaucoma Agents
Glaucoma is treated by:
Common anti-glaucoma agents
Ocular Anti-allergic Drugs
Mast cell stabilizers used as Ocular A…
ophthalmologist
beta blockers, adrenergic agonists... miotics... carbonic anhydrase…
Mast cell stabilizers ... Antihistamine
lodoxamide (Alomide) and ... Cromolyn sodium (Crolom)
Glaucoma is treated by:
ophthalmologist
Common anti-glaucoma agents
beta blockers, adrenergic agonists... miotics... carbonic anhydrase…
6 terms
Pharm: Glaucoma
Quick reminder of basic mechanism
Distinguish between primary open-angle…
Give three symptoms of closed-angle gl…
Apply the two drug categories used and…
Ciliary epithelium (β1)... Ciliary muscle (M3)... -β1 facilitates…
Closed angle glaucoma- dilated iris can occlude the outflow d…
-Eye pain... -Nausea and vomitting... -SUDDEN onset of visual distu…
-iridectomy surgery is the eventual fix... -treat with cholinomi…
Quick reminder of basic mechanism
Ciliary epithelium (β1)... Ciliary muscle (M3)... -β1 facilitates…
Distinguish between primary open-angle…
Closed angle glaucoma- dilated iris can occlude the outflow d…
23 terms
glaucoma
glaucoma
glaucoma patho and etiology
primary glaucoma
secondary or aquired glaucoma
is a condition characterized by optic neuropathy with gradual…
aqueous humor occupies anterior, posterior chambers of the ey…
open angle glaucoma... angle closure glaucoma... both terms refer t…
eye injury... prolonged steroid use
glaucoma
is a condition characterized by optic neuropathy with gradual…
glaucoma patho and etiology
aqueous humor occupies anterior, posterior chambers of the ey…
73 terms
Glaucoma
Definition of Glaucoma?
Which of the following is not a cause…
T/F. With glaucoma, peripheral vision…
Open Angle Glaucoma or (POAG) generall…
-a group of disorders characterized by damage to the optic ne…
(B). Intraocular pressure associated with Glaucoma can be cau…
True.
both. (bilateral). Generally a chronic illness.
Definition of Glaucoma?
-a group of disorders characterized by damage to the optic ne…
Which of the following is not a cause…
(B). Intraocular pressure associated with Glaucoma can be cau…
25 terms
Chapter 23: Glaucoma
This is a localized ocular disease cha…
This constitutes approximately 10% of…
This is a chronic progressive bilatera…
Therapy for this may restrict a health…
Glaucoma
Primary Angle-Closure Glaucoma
Primary Open-Angle Glaucoma
Ocular Hypertension
This is a localized ocular disease cha…
Glaucoma
This constitutes approximately 10% of…
Primary Angle-Closure Glaucoma
83 terms
Pharmacology- Glaucoma
Figure of drugs and their sites of act…
What is the effect of pilocarpine (mus…
Contraction of ciliary muscle causes d…
Relaxation of suspensory ligaments con…
Contraction of both (Miosis-pupil constriction)
Suspensory ligaments
Refractive power
Figure of drugs and their sites of act…
What is the effect of pilocarpine (mus…
Contraction of both (Miosis-pupil constriction)
41 terms
Glaucoma Drugs
Flow of aqueous humor in the normal eye.
Glaucoma
Open Angle Glaucoma... - cause?... - how qui…
Closed Angle (Acute) Glaucoma... - most c…
ciliary body --> posterior chamber --> anterior chamber --> t…
a disease of the optic nerve and one of the leading causes of…
clogging of the trabecular meshwork with decreased drainage o…
MEDICAL EMERGENCY (patients can lose all vision in the eye wi…
Flow of aqueous humor in the normal eye.
ciliary body --> posterior chamber --> anterior chamber --> t…
Glaucoma
a disease of the optic nerve and one of the leading causes of…
40 terms
Topical Agents (Pharm)
Vaginal Antifungal
Vaginal Antibiotic
Vaginal Antiprotozoal
Otic wax softener
Clotrimazole (Gyne-Lotrimin)
Clindamycin Phosphate (Cleocin cream 2%)
Metronidazole (Metrogel)
Carbamide peroxide 6.5% (Debrox)
Vaginal Antifungal
Clotrimazole (Gyne-Lotrimin)
Vaginal Antibiotic
Clindamycin Phosphate (Cleocin cream 2%)
38 terms
Glaucoma-Peterson
Aqueous Humor
Aqueous humor production
Aqueous humor leaves the eye through
Intra-ocular Pressure (IOP)
-Fluid in the space between the lens and the cornea.
-influenced by:... 1. Pressure gradients, blood pressure, and in…
-filtration through the trabecular meshwork to the Schlemm's…
-Not constant, changes with pulse, blood pressure, forced exp…
Aqueous Humor
-Fluid in the space between the lens and the cornea.
Aqueous humor production
-influenced by:... 1. Pressure gradients, blood pressure, and in…
33 terms
Glaucoma
lower than 50... african american... monocul…
what theory behind for the causes chan…
1-the SPCA , 2-retinal arterioles of t…
5db
when to lower target pressure and additional 10%?
ischemic ... ischemic 2... lamina distortion theory (quigley)
ischemic: the blood supply of ON from __1___and the surface o…
20% loss in NFL is equaibalent to what dB field loss?
lower than 50... african american... monocul…
when to lower target pressure and additional 10%?
what theory behind for the causes chan…
ischemic ... ischemic 2... lamina distortion theory (quigley)
31 terms
Glaucoma
lower than 50... african american... monocul…
5db
3 IOP... 2 VF... gonio ... pachymetry ... evalate…
No glauc... high myope... -rim okay, slopoing
when to lower target pressure and additional 10%?
20% loss in NFL is equaibalent to what dB field loss?
what must you get before starting glauc tx?
Glauc?
lower than 50... african american... monocul…
when to lower target pressure and additional 10%?
5db
20% loss in NFL is equaibalent to what dB field loss?
52 terms
Glaucoma
Glaucoma
Open Angle glaucoma
Close and Open glaucoma
True
a group of ocular disorders that lead to an optic neuropathy…
What type of glaucoma is the second leading cause of blindness
The (2) types of glaucoma
T/F: Open angle glaucoma accounts for the great majority of c…
Glaucoma
a group of ocular disorders that lead to an optic neuropathy…
Open Angle glaucoma
What type of glaucoma is the second leading cause of blindness
52 terms
Glaucoma
Glaucoma
Open Angle glaucoma
Close and Open glaucoma
True
a group of ocular disorders that lead to an optic neuropathy…
What type of glaucoma is the second leading cause of blindness
The (2) types of glaucoma
T/F: Open angle glaucoma accounts for the great majority of c…
Glaucoma
a group of ocular disorders that lead to an optic neuropathy…
Open Angle glaucoma
What type of glaucoma is the second leading cause of blindness
24 terms
DEENT GLAUCOMA
NS Beta Blockers
Beta 1 Selective blocker
Open & Acute angle glaucoma
BB MOA
Timolol... Carteolol... Metipranolol... Levobunolol
Betaxolol - works on all colored eyes
In open-angle glaucoma (chronic), fluid does not flow freely…
Blocks receptor on the ciliary body.
NS Beta Blockers
Timolol... Carteolol... Metipranolol... Levobunolol
Beta 1 Selective blocker
Betaxolol - works on all colored eyes
Ch. 43 drugs used to treat glaucoma and other eye disorders
corneoscleral coat
choroid coat
retina
cornea
the protective external layer
nutritive middle vascular layer
light-sensitive inner layer
the outermost sheath of the anterior eyeball.
corneoscleral coat
the protective external layer
choroid coat
nutritive middle vascular layer
22 terms
Glaucoma
Plays a role in the pathogenesis of gl…
Aqueous Humor
Two ways the aqueous humor can exit th…
what is normal IOP
An increase in Intraocular pressure
1) cillary body is important for the formation of aqueous hum…
1) The first way is the conventional way: "the canal of schle…
15.5
Plays a role in the pathogenesis of gl…
An increase in Intraocular pressure
Aqueous Humor
1) cillary body is important for the formation of aqueous hum…
31 terms
Glaucoma Pharmacotherapy (& treatment)
beta blockers
prostaglandins
cholinergic agents... pilocarpine... carbac…
pilocarpine
decrease aqueous humor secretion
increases outflow through uveoscleral route; some trabecular…
miosis by contraction of the iris sphincter muscle... increased…
DOC for acute glaucoma... muscarinic... ocusert... eye or brow ache, a…
beta blockers
decrease aqueous humor secretion
prostaglandins
increases outflow through uveoscleral route; some trabecular…
14 terms
Glaucoma
Drug induced glaucoma
Goal of therapy
non pharm therapy
monitoring parameters
Anticholinergics e.g atropine... Glucocorticoids... Higher risk fo…
decrease intraocular pressure by 20-30%... Stabilize optic nerve…
open angle glaucoma: Laser trabeculoplasty, incisional glauco…
Measure IOP after starting therapy/medication change every 4-…
Drug induced glaucoma
Anticholinergics e.g atropine... Glucocorticoids... Higher risk fo…
Goal of therapy
decrease intraocular pressure by 20-30%... Stabilize optic nerve…
10 terms
Middle 10 on Drug List #8
Fosamax Plus D
Differin
Bactroban
BenzaClin
Bone Strengthener ... Alendronate/ Vitamin D... osteoporosis
Retinoid ... Adapalene... Acne vulgaris
Topical antibiotic ... Mupirocin... Skin Infection
Topical antibiotic ... Clindamycin/ benzoyl peroxide ... acne
Fosamax Plus D
Bone Strengthener ... Alendronate/ Vitamin D... osteoporosis
Differin
Retinoid ... Adapalene... Acne vulgaris
37 terms
Glaucoma
epidemiology
aqueous humor
glaucoma
primary open angle glaucoma
#1 cause of preventable blindness in U.S.... >3 million people…
Clear fluid produced by ciliary body at approximate rate of 2…
80+ subsets of glaucoma... Group of ocular diseases with variou…
#1 most common type of glaucoma... 60% of all glaucoma patients…
epidemiology
#1 cause of preventable blindness in U.S.... >3 million people…
aqueous humor
Clear fluid produced by ciliary body at approximate rate of 2…
31 terms
Glaucoma
Parameters of glaucoma
Most common mechanism in glaucoma
Normal IOP
Aqueous is produced in the?
Increase IOP... Optic nere cupping... Visual field loss
Impaired aqueous outflow
16 +/- 5 , peak is early morning
Ciliary body
Parameters of glaucoma
Increase IOP... Optic nere cupping... Visual field loss
Most common mechanism in glaucoma
Impaired aqueous outflow
17 terms
Glaucoma
Primary open angle glaucoma is caused…
Prolonged steroid use may cause what e…
What ethnicity is more likely to have…
Which ethnic group is more likely to h…
increased intraocular fluid production with decreased removal.
glaucoma
Asians
African American
Primary open angle glaucoma is caused…
increased intraocular fluid production with decreased removal.
Prolonged steroid use may cause what e…
glaucoma
20 terms
Quiz 2 Respiratory agents, Allergies, Topical Agents
RESPIRATORY AGENTS:... ASTHMA/COPD/ Beta…
RESPIRATORY AGENTS:... ASTHMA/COPD/ Bet…
RESPIRATORY AGENTS:... ASTHMA/COPD/ Beta…
RESPIRATORY AGENTS:... ASTHMA/COPD/ ANTI…
albuterol sulfate
albuterol Sulfate
albuterol Sulfate
(titropium)
RESPIRATORY AGENTS:... ASTHMA/COPD/ Beta…
albuterol sulfate
RESPIRATORY AGENTS:... ASTHMA/COPD/ Bet…
albuterol Sulfate
Glaucoma
What is Glaucoma?
flow of aqueous humor
Two types of glaucoma
Glaucoma epidemiology
Ocular disorder that leads to an optic neuropathy charecteriz…
Made in the ciliary body, travels to posterior chamber, throu…
Primary open angle glaucoma... Primary/Acute Angle closure Glau…
Primary open angle glaucoma (POAG) is second leading cause of…
What is Glaucoma?
Ocular disorder that leads to an optic neuropathy charecteriz…
flow of aqueous humor
Made in the ciliary body, travels to posterior chamber, throu…
28 terms
Glaucoma
Epidemiology
Aqueous Humor
Aqueous Humor Drainage
Primary Open Angle Glaucoma
- # cause of preventable blindness in US... - 3 million in US... -…
- Clear fluid... - Produced by ciliary body 2.5mL/minute... - Provi…
1. Trabecular meshwork... 2. Uveoscleral pathway
- 60%... - Not caused by other ocular/systemic diseases
Epidemiology
- # cause of preventable blindness in US... - 3 million in US... -…
Aqueous Humor
- Clear fluid... - Produced by ciliary body 2.5mL/minute... - Provi…
54 terms
Cholinergic/Anticholinergic Agents CNS
Acetylcholine functional groups
cholinergic receptors
Acetylcholine Receptor Binding
Cholinergic Effects
quaternary ammonium -always have a positive charge... Acylozy…
1. Muscarinic ... 2. Nicotinic
Ionic interaction ... Hydrogen bonding
-Rest & Digest ... -Stimulate contraction of smooth muscle in GI…
Acetylcholine functional groups
quaternary ammonium -always have a positive charge... Acylozy…
cholinergic receptors
1. Muscarinic ... 2. Nicotinic
5 terms
Pharmacology Module 16 Miscellaneous Drugs
dermatologic agents
opthalmic topicals
glaucoma
drugs to treat glaucoma
applied topically, many OTC, they can alter inflammation, blo…
prevent systemic absorption... ointments have higher drug concen…
visual field loss, secondary to optic nerve damage... open angl…
beta blocker: eye drop that decreases the production of aqueo…
dermatologic agents
applied topically, many OTC, they can alter inflammation, blo…
opthalmic topicals
prevent systemic absorption... ointments have higher drug concen…
38 terms
Angle Closure Glaucoma
sup bc narrowest angle
most doc recommend LPI ... -either PAS an…
PAC
PACG
Where does PAS happen more?
what is the tx to primary angle closure glauc? What must the…
What would the pt have if you find this on gonio with an inc…
What would the pt have if you find this on gonio with inc IOP…
sup bc narrowest angle
Where does PAS happen more?
most doc recommend LPI ... -either PAS an…
what is the tx to primary angle closure glauc? What must the…
30 terms
Group 21 and 22 Brand and Class
Diflucan
Nizoral
Nystatin
Lamisil
Antifungal
Antifungal
Antifungal
Antifungal
Diflucan
Antifungal
Nizoral
Antifungal
29 terms
Glaucoma
what is the number one cause of preven…
what is a clear fluid produced by cili…
what provides the nutritional needs to…
what two areas does the aqueous humor…
glaucoma
aqueous humor
aqueous humor
the trabecular meshwork and the uveoscleral pathway
what is the number one cause of preven…
glaucoma
what is a clear fluid produced by cili…
aqueous humor
29 terms
Glaucoma
what is the number one cause of preven…
what is a clear fluid produced by cili…
what provides the nutritional needs to…
what two areas does the aqueous humor…
glaucoma
aqueous humor
aqueous humor
the trabecular meshwork and the uveoscleral pathway
what is the number one cause of preven…
glaucoma
what is a clear fluid produced by cili…
aqueous humor
69 terms
Medications Only- Glaucoma, Thyroid, Meningitis, Immunocomp. Infections
Betaxolol
Carteolol
Levobunolol
Metipranolol
Ophthalmic Beta Blocker- Relatively Selective... Glaucoma
Ophthalmic Beta Blocker- Nonspecific with intrinsic sympathom…
Ophthalmic Beta Blocker- Nonspecific... Glaucoma
Ophthalmic Beta Blocker- Nonspecific... Glaucoma
Betaxolol
Ophthalmic Beta Blocker- Relatively Selective... Glaucoma
Carteolol
Ophthalmic Beta Blocker- Nonspecific with intrinsic sympathom…
110 terms
glaucoma
glaucoma is the 2nd leading cause of _…
T or F... closed-angle glaucoma is the m…
describe what is glaucoma
increased intraocular pressure (IOP) d…
blindness
F... primary open angle glaucoma is the most common form
group of ocular disorders that lead to optic neurpathy... - chan…
retinal cells
glaucoma is the 2nd leading cause of _…
blindness
T or F... closed-angle glaucoma is the m…
F... primary open angle glaucoma is the most common form
65 terms
Glaucoma
Which is true of glaucoma?... 1. More sev…
What are three changes that could lead…
T/F Elevated intraocular pressure (IOP…
Types of glaucoma
half of all patients are unaware
changes in optic disk... loss of visual sensitivity and field... el…
True
Primary, congenital, or secondary... Closed vs. open angle... Chron…
Which is true of glaucoma?... 1. More sev…
half of all patients are unaware
What are three changes that could lead…
changes in optic disk... loss of visual sensitivity and field... el…
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