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Study sets matching "toxicology final"

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Study sets matching "toxicology final"

118 terms
Toxicology
A class of drugs that increase alertne…
Something that counteracts the action…
Potent sedative-hypnotics historically…
The family of sedative-hypnotics most…
amphetamines
antagonist
barbiturates
benzodiazepines
A class of drugs that increase alertne…
amphetamines
Something that counteracts the action…
antagonist
46 terms
Toxicology
Amphetamines
Analgesics
Antihistamines
Barbiturate
a sympathomimetic amine that has a stimulating effect on both…
agents that relieve pain without causing loss of consciousnes…
antagonists of the H1 or H2 histamine receptors that are used…
any of a class of sedative-hypnotic agents derived from barbi…
Amphetamines
a sympathomimetic amine that has a stimulating effect on both…
Analgesics
agents that relieve pain without causing loss of consciousnes…
96 terms
Toxicology
Poisoning
Overdose
Toxicology
Hazard
Clinical toxicity secondary to accidental exposure
Intentional exposure with intent of causing self-injury or de…
Study of the harmful effects of chemical, biological and phys…
Likelihood that injury will occur in a given situation or set…
Poisoning
Clinical toxicity secondary to accidental exposure
Overdose
Intentional exposure with intent of causing self-injury or de…
137 terms
Toxicology
Poison Control Phone Number
Who is at greatest risk for adult pois…
1/5 of adult poisonings are attributed…
What are some ways people get poisoning?
1 (800) 222-1222
20-59 year old men
Suicide
- CO... - Opioids... - Antidepressants... - Benzos... - Sedatives... - ETOH…
Poison Control Phone Number
1 (800) 222-1222
Who is at greatest risk for adult pois…
20-59 year old men
48 terms
TOXICOLOGY
POISONING is both ________ and _______…
Compounds that are created to induce p…
What is the primary determinant of tox…
What are the 2 functions of studying t…
Situational; quantitative - any substance at a specific dose/…
Contain labeling with the word "DANGER" and the word "POISON"…
DOSE; also dependent on DURATION OF TIME that the chemicals a…
1) Protection of humans and other organisms from adverse effe…
POISONING is both ________ and _______…
Situational; quantitative - any substance at a specific dose/…
Compounds that are created to induce p…
Contain labeling with the word "DANGER" and the word "POISON"…
41 terms
Toxicology
Which of the following questions is of…
A 30-year-old male, who ingested an un…
When caring for a patient with a surfa…
Most poisonings occur via the ________…
Answer: D... Rationale: Determining what the patient ingested,…
Answer: A... Rationale: If the patient vomits, examine the conte…
Answer: B... Response: Emergency care for a patient with a surfa…
Answer: B... Rationale:Approximately 80% of all poisonings occur…
Which of the following questions is of…
Answer: D... Rationale: Determining what the patient ingested,…
A 30-year-old male, who ingested an un…
Answer: A... Rationale: If the patient vomits, examine the conte…
49 terms
Toxicology
Methadone
Opiate/Opioid
Phencyclidine (PCP)
Poison
A synthetic narcotic, possessing pharmacological actions simi…
refers to any of a group of naturally occurring (poppy plant)…
A potent analgesic and anesthetic used in veterinary medicine…
Any substance, which, when relatively small amounts are inges…
Methadone
A synthetic narcotic, possessing pharmacological actions simi…
Opiate/Opioid
refers to any of a group of naturally occurring (poppy plant)…
49 terms
toxicology
Poison
when should activated charcoal be used
when should a gastric lavage be perfor…
what is a contraindication for gastric…
any substance that produces a harmful physiological or psycho…
no antidotes are available and when it can be administered wi…
highly toxic substance is consumed within the past hour (rare…
pt cannot protect airway... ALOC... ingestion of low-viscosity hydr…
Poison
any substance that produces a harmful physiological or psycho…
when should activated charcoal be used
no antidotes are available and when it can be administered wi…
38 terms
Toxicology
Toxicology
Similarities between pharm and tox?
xenobiotic
How to pharm and tox differ?
-science of poisons (toxicants)... -Diagnoses and treatment/prev…
1. drugs can be poisons and poisons can be drugs (difference…
foreign chemicals that the body does not produce
Phamcologist is only interested in therapeutic drugs
Toxicology
-science of poisons (toxicants)... -Diagnoses and treatment/prev…
Similarities between pharm and tox?
1. drugs can be poisons and poisons can be drugs (difference…
69 terms
Toxicology
Prozac, Paxil, and Zoloft are all exam…
Which of the following is NOT associat…
Which of the following does NOT typica…
Your patient is a 60-year-old male com…
c. Selective serotonin reuptake inhibitors
c. Hyperactivity
b. Organophosphate
d. Supportive management
Prozac, Paxil, and Zoloft are all exam…
c. Selective serotonin reuptake inhibitors
Which of the following is NOT associat…
c. Hyperactivity
39 terms
Toxicology
What is the most common OTC overdose?
Early presentation of OD of this drug…
T/F: With acetaminophen OD, LFTs rise…
18-24 hours after OD of this drug, the…
Acetaminophen
Acetaminophen
TRUE
Acetaminophen
What is the most common OTC overdose?
Acetaminophen
Early presentation of OD of this drug…
Acetaminophen
31 terms
Toxicology
A patient presents with anorexia nause…
A patient presents with right upper qu…
A patient presents with abdominal pain…
how long before liver failure or resol…
Stage 1 Acetaminophen poisoning
Stage two acetaminophen poisoning.
Stage three acetaminophen poisoning.
Four days - two weeks
A patient presents with anorexia nause…
Stage 1 Acetaminophen poisoning
A patient presents with right upper qu…
Stage two acetaminophen poisoning.
5 terms
Toxicology
Toxicology
Job of toxicologist
Degree of toxicity
Intoxicant
Study of drugs,poisons, and other toxic substances
To identify a toxin and determine likely effect on the indivi…
Depends on: How much enters the body and over what period of…
Alcohol... Need lots of it to be lethal
Toxicology
Study of drugs,poisons, and other toxic substances
Job of toxicologist
To identify a toxin and determine likely effect on the indivi…
12 terms
Toxicology
Poison
Toxin
Antidote
Decontamination
...
...
...
...
Poison
...
Toxin
...
12 terms
Toxicology
Toxicology
Toxicologists
4 ways exposure to toxins happen
Toxic substances can be classified by…
The study of poisons.
Study of the harmful effects these substances may have on the…
Ingesting them through the gastrointestinal system. ... Inhaling…
Intentionally to treat illness or relieve pain. ... Accidentally…
Toxicology
The study of poisons.
Toxicologists
Study of the harmful effects these substances may have on the…
25 terms
Toxicology
Toxicology
Types of toxicology
Toxicologists
Toxin
the study of the adverse effects of chemical or physical agen…
Environmental, consumer, medical, clinical, forensic.
Charged with the responsibility for detecting and identifying…
Substance that causes injury to the health of a living thing…
Toxicology
the study of the adverse effects of chemical or physical agen…
Types of toxicology
Environmental, consumer, medical, clinical, forensic.
20 terms
Toxicology
Toxicology
Poison
Toxin
Substance abuse
Study of toxic or poisonous substances
Substance whose chemical actions can damage the body function…
A poisonous substance produced by bacteria, animals, or plant…
Misuse of any substance to produce a desired effect
Toxicology
Study of toxic or poisonous substances
Poison
Substance whose chemical actions can damage the body function…
9 terms
Toxicology
Acetaminophen
Anticholinergics
Warfarin
Opioid
Acetylcysteine
Physostigmine
Phytonadione
Naloxone
Acetaminophen
Acetylcysteine
Anticholinergics
Physostigmine
67 terms
toxicology
temp/HR/BP: inc... Pupils: large... Skin: mo…
antidotes: mental status reversal
antidote: Bicarbonate
antidote for Calcium Channel Blockers
Serotonergic
Naloxone, flumazanil, physostigmine
TCA's, salicylates, toxin-induced acidosis, any Na+ channel b…
Calcium, insulin
temp/HR/BP: inc... Pupils: large... Skin: mo…
Serotonergic
antidotes: mental status reversal
Naloxone, flumazanil, physostigmine
20 terms
Toxicology
Addiction
Antidote
Delirium Tremens-DTs
Emesis
A state of overwhelming obsession or physical need to continu…
A substance that is used to neutralize or counteract a posion
A severe withdrawal syndrome seen in alcoholics who are depri…
Vomiting
Addiction
A state of overwhelming obsession or physical need to continu…
Antidote
A substance that is used to neutralize or counteract a posion
20 terms
Toxicology
Pathogens
Emergent Diseases
Spread and Discovery of diseases
Toxicology
Disease causing organism. Ex) Viruses, Bacteria, Protozoans,…
A disease never known before or one which has been absent for…
Growing human populations push into remote areas where they e…
Study of poisons and their effects on livingsystems
Pathogens
Disease causing organism. Ex) Viruses, Bacteria, Protozoans,…
Emergent Diseases
A disease never known before or one which has been absent for…
24 terms
Toxicology
Toxicology
Toxicity
dose
exposure
the study of poisons and their mechanism of action
the adverse effects that a chemical may produce
the actual amount of substance introduced into a body
contact providing the opportunity of obtaining a poisonous dose
Toxicology
the study of poisons and their mechanism of action
Toxicity
the adverse effects that a chemical may produce
27 terms
Toxicology
Amphetamines
Analgesics
Antihistamines
Barbiturate
A sympathomimetic amine that has a stimulating effect on both…
Agents that relieve pain without causing loss of consciousness
Antagonists of the H1 or H2 histamine receptors that are used…
Any of a class of sedative-hypnotic agents derived from barbi…
Amphetamines
A sympathomimetic amine that has a stimulating effect on both…
Analgesics
Agents that relieve pain without causing loss of consciousness
35 terms
Toxicology
Drug
Poison
Illicit Drugs
Hallucinagens
natural or synthetic substance designed to affect humans
...
...
...
Drug
natural or synthetic substance designed to affect humans
Poison
...
15 terms
Toxicology
Anticholinergic toxidrome
Sympathomimetic toxidrome
Differences between Sympathomimetic an…
Opioid(narcotic)/Sedative/Etoh toxidrome
Hyperthermia (hot as a hare), Mydriasis (blind as bat), Dry s…
tachycardia, dysrhythmias, HTN, diaphoresis, goosebumps, AMS…
1. skin (diaphoretic vs dry)... 2. Pupils reaction (reactive vs…
1. Miosis... 2. Resp depression (due to dec. sensitivity of resp…
Anticholinergic toxidrome
Hyperthermia (hot as a hare), Mydriasis (blind as bat), Dry s…
Sympathomimetic toxidrome
tachycardia, dysrhythmias, HTN, diaphoresis, goosebumps, AMS…
25 terms
Toxicology
toxicology
significance of toxicology
birth of toxicology
post WWII
study of adverse effects of chemical, physical, or biological…
needed in order to understand effects of chemicals on organis…
1920's-30's - Copeland Act (1930s) - guaranteed earned wages…
minamata (1953) - mercury poisoning from eating seafood that…
toxicology
study of adverse effects of chemical, physical, or biological…
significance of toxicology
needed in order to understand effects of chemicals on organis…
85 terms
Toxicology
Toxicology
Toxicant
Living organism
Exposure
The study of the adverse effects of a toxic ant on living org…
Any agent capable of producing a deleterious response in a bi…
A sac of water with target sites, storage depots and enzymes.
Chemical come in contact with and are absorbed into organisms
Toxicology
The study of the adverse effects of a toxic ant on living org…
Toxicant
Any agent capable of producing a deleterious response in a bi…
19 terms
Toxicology
Common antidotes ... Acetylcysteine
Common antidotes... Dimercaprol
Common antidotes... EDTA, CaNA2
Common antidotes... Penicillamine
Acetaminophen
Lead, mercury, arsenic
Lead
Lead, mercury, copper
Common antidotes ... Acetylcysteine
Acetaminophen
Common antidotes... Dimercaprol
Lead, mercury, arsenic
45 terms
Toxicology
Toxicology
Chemical associated with fish
Chemical associated with meat
Chemical associated with buns
The study of the effects of chemicals on living organisms
Omega 3 fats (reduce heart disease)
Dioxins
Acrylamide (carcinogen)
Toxicology
The study of the effects of chemicals on living organisms
Chemical associated with fish
Omega 3 fats (reduce heart disease)
14 terms
Toxicology
Matthieu orfilia
Intoxicant
Poisin
Postmortem
Father of tox ... Worked with arsenic
Alcohol
Cyanide requires a little to be fatal
Medical rxaminer
Matthieu orfilia
Father of tox ... Worked with arsenic
Intoxicant
Alcohol
Toxicology
Acetaminophen P
Organophosphates P
Iron salts P
Digoxin P
Acetylcysteine A
Atropine A
Deforoxamine A
Digibind A
Acetaminophen P
Acetylcysteine A
Organophosphates P
Atropine A
30 terms
Toxicology
Carbon Monoxide
Aversive agents
Toxic incidents
Emetics
Cherry colored flush of skin and mucous membranes. Cause tiss…
Unpleasantly flavored substances added to poisonous household…
10 million annually, 5000 fatal
Trigger vomiting, contraindicated in ingestion of corrosives
Carbon Monoxide
Cherry colored flush of skin and mucous membranes. Cause tiss…
Aversive agents
Unpleasantly flavored substances added to poisonous household…
33 terms
Toxicology
Toxicology
Poison
The dose
Forensic toxicology
The science of poisons (toxicants). The study of adverse effe…
Any substance that can produce adverse effects on biological…
What determines that a substance is not a poison?
This area of toxicology deals with the detection of poisoning…
Toxicology
The science of poisons (toxicants). The study of adverse effe…
Poison
Any substance that can produce adverse effects on biological…
246 terms
Toxicology
Veratrum
Burley Tobacco
Lupine
Poison Hemlock
Glyco-alkaloids (teratogenic alkaloids)
Piperidine Alkaloid
Piperidine Alkaloid
Piperidine Alkaloid
Veratrum
Glyco-alkaloids (teratogenic alkaloids)
Burley Tobacco
Piperidine Alkaloid
24 terms
Toxicology
anhidrosis
mydriasis
mydriasis
absent bowel sounds
anticholinergics
anticholinergics
serotonergic
anticholinergics
anhidrosis
anticholinergics
mydriasis
anticholinergics
58 terms
Toxicology
Ethanol
Ethanol
Capillary and arterial blood
Enzymatic using alcohol dehydrogenase…
Most common abused drug
Causes diuresis by inhibiting ADH
Specimen for ethanol
Preferred method for ethanol
Ethanol
Most common abused drug
Ethanol
Causes diuresis by inhibiting ADH
14 terms
Toxicology
Toxidrome
Opiate Overdose
Cholinergic Overdose
Hallucinogenic Overdose
A syndrome, or group of signs and symptoms, caused by a dange…
Classic triad of coma, pinpoint pupils, and respiratory depre…
DUMBBELS: Defecation, Urination, Miosis, Bradycardia, Broncho…
Disorientation, hallucinations, hyperactive bowel sounds, pan…
Toxidrome
A syndrome, or group of signs and symptoms, caused by a dange…
Opiate Overdose
Classic triad of coma, pinpoint pupils, and respiratory depre…
18 terms
toxicology
addiction
antidote
delirium tremens (DTs)
emesis
a state of overwhelming obsession or physical need to continu…
a substance that is used to neutralize or counteract a poison
a severe withdrawal syndrome even in alcoholics who are depri…
vomiting
addiction
a state of overwhelming obsession or physical need to continu…
antidote
a substance that is used to neutralize or counteract a poison
30 terms
toxicology
N-acetylcysteine (NAC)
Atropine
Calcium EDTA
Deferoxamine
APAP, hepatotoxins... Oral/IV Give STAT
Organophosphates, nerve agents... Large doses
Lead... NO Na EDTA
Iron... IV, Not IM
N-acetylcysteine (NAC)
APAP, hepatotoxins... Oral/IV Give STAT
Atropine
Organophosphates, nerve agents... Large doses
69 terms
Toxicology
Charcoal, activated
Indications for charcoal
Functional category: acts chemically
Contraindications for charcoal activated
Non-specific adsorption of many drugs and toxins by chemical…
Single-dose administration for the prevention of absorption o…
absorbents... chelating agents... antibodies... chemical group exchang…
GI ileus or obstruction... acid or alkali ingestions... drowsy or u…
Charcoal, activated
Non-specific adsorption of many drugs and toxins by chemical…
Indications for charcoal
Single-dose administration for the prevention of absorption o…
49 terms
Toxicology
Toxicology:
Four major disciplines of toxicology
Dose-response relationship:
TD50
The science of poisons, including their source, chemical comp…
Mechanistic : seeks to explain the cellular and biochemical e…
there will be an increase in the toxic response as the dose i…
Dose that would be predicted to produce a toxic response in 5…
Toxicology:
The science of poisons, including their source, chemical comp…
Four major disciplines of toxicology
Mechanistic : seeks to explain the cellular and biochemical e…
62 terms
Toxicology
Toxicology
types of toxicology
Mathieu Orfila
James Marsh
the study of the adverse effects of chemicals or physical age…
*enviornmental-air, water, soil... *consumer-food, cosmetics, dr…
known as the father of forensic toxicology, published in 1814…
Marsh test... highly effective in finding arsenic
Toxicology
the study of the adverse effects of chemicals or physical age…
types of toxicology
*enviornmental-air, water, soil... *consumer-food, cosmetics, dr…
35 terms
Toxicology
controlled substances
odorless
type s
pyrolysis
drugs that are restricted by the law
a characteristic of an ideal poison, that it cannot be readil…
a classification of poisoner who targets their victims
type of gas chromatograph that uses heat to decompose the com…
controlled substances
drugs that are restricted by the law
odorless
a characteristic of an ideal poison, that it cannot be readil…
61 terms
Toxicology
Bhopal toxin
Toxic chemical
Toxic substance
Toxicant
Methyl Isocyanate: killed > 3000 and injured more than 100,000
any chemical which can cause death or harm to animals or humans
does not differentiate between chemical or mixture of chemica…
any chemical that can potentially produce harm
Bhopal toxin
Methyl Isocyanate: killed > 3000 and injured more than 100,000
Toxic chemical
any chemical which can cause death or harm to animals or humans
43 terms
Toxicology
condition of being secure rom threat o…
inherent ability of an agent to cause…
expected frequency of occurrence of un…
likelihood that an injury will occur i…
Safety
Toxicity
Risk
Hazard
condition of being secure rom threat o…
Safety
inherent ability of an agent to cause…
Toxicity
28 terms
Toxicology
Fast or irregular pulse
Respiratory depression
Hypothermia
Hyperthermia
Salbutamol, antimuscarinic, tricyclic, quinine, phenothiazine…
Opiates, benzodiazepine
Phenothiazines, barbiturates
Amphetamines, ... MAOIs, ... cocaine, ... ecstasy
Fast or irregular pulse
Salbutamol, antimuscarinic, tricyclic, quinine, phenothiazine…
Respiratory depression
Opiates, benzodiazepine
23 terms
toxicology
analytical toxicology
clinical toxicology
Forensic toxicology
Occupational toxicology
identification of unknown toxicant through analysis of body f…
administration of antidotes, if known and available, to count…
analytical, diagnostic and clinical toxicology within the leg…
the study of the results of occupational exposure to toxicant…
analytical toxicology
identification of unknown toxicant through analysis of body f…
clinical toxicology
administration of antidotes, if known and available, to count…
36 terms
Toxicology
narcotics what
narcotics CNS
narcotics symptom
narcotics treat
opiate-morphine, meperidine, codeine, heroin, methadone
depressant
pin point pupils, hypoventilation, hypotension
support ABC
narcotics what
opiate-morphine, meperidine, codeine, heroin, methadone
narcotics CNS
depressant
29 terms
toxicology
Drug
Hallucination
Narcotic
Analgesic
natural or synthetic substance that's used to produce physiol…
substances that induces changes in normal thought processes,…
drug that induces sleep and depresses vital body functions su…
substance that lessens or eliminates pain
Drug
natural or synthetic substance that's used to produce physiol…
Hallucination
substances that induces changes in normal thought processes,…
16 terms
Toxicology
Phytonadione (Vitamin K)... -Indication
Phytonadione (Vitamin K)... -Dosing (no e…
Phytonadione (Vitamin K)... -Dosing (warf…
Phytonadione (Vitamin K)... -Routes of Ad…
Patients with INR > 10 w/o evidence of bleed
2.5-5 mg PO
10 mg IV
PO & IV preferred... IM → hematoma... SQ → erradic absorption
Phytonadione (Vitamin K)... -Indication
Patients with INR > 10 w/o evidence of bleed
Phytonadione (Vitamin K)... -Dosing (no e…
2.5-5 mg PO
4 of 10