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Study sets matching "utcop pharmacology"

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Study sets matching "utcop pharmacology"

22 terms
Pharmacology Diuretics- Bahouth UTCOP
Act on proximal convoluted tubules
Act on loop of hence (loop diuretics)
Act on Distal convoluted tubule
Act on collecting ducts
Carbonic anhydrase inhibitors- acetazolamide (Diamox)... Osmotic…
Furosemide (Lasix)... Bumetanide (Bumex)... Torsemide (Demadex)
Hydrochlorothiazide ... Chlorthalidone ... Metolazone... Quinothazone…
Arginine Vasopressin... Demopressin... Demeclocyclin
Act on proximal convoluted tubules
Carbonic anhydrase inhibitors- acetazolamide (Diamox)... Osmotic…
Act on loop of hence (loop diuretics)
Furosemide (Lasix)... Bumetanide (Bumex)... Torsemide (Demadex)
18 terms
TB
* 6 Risk Factors for TB
* Patients with latent TB can best be…
* Which drug is considered the most im…
* Induration of > or equal to 5 for HI…
1. Foreign travel/residence... 2. HIV... 3. Homelessness... 4. Residen…
Infected, but NOT contagious
Rifampin - backbone of anti-TB therapy
...
* 6 Risk Factors for TB
1. Foreign travel/residence... 2. HIV... 3. Homelessness... 4. Residen…
* Patients with latent TB can best be…
Infected, but NOT contagious
205 terms
Pharmacology II Exam I
Cerebral Cortex
Nucleus Accumbens
Orbitofrontal Cortex
Basal Ganglia
Processes association, motor, and somatosensory information.…
Part of the Limbic System, responsible for Motivation
Part of the Limbic System, responsible for Decision making.
Contains the substantia nigra, STRIATUM, putamen, globus pall…
Cerebral Cortex
Processes association, motor, and somatosensory information.…
Nucleus Accumbens
Part of the Limbic System, responsible for Motivation
190 terms
Final Exam Pharm/MC
DoA: Define Addiction
DoA: Define Tolerance
DoA: Withdrawal
DoA: Loss of Control
Compulsive drug use
a) Markedly increased amounts of the substance to achieve int…
o Characteristic withdrawal syndrome for the substance... o The…
-The substance is often taken in *larger amounts* or over a *…
DoA: Define Addiction
Compulsive drug use
DoA: Define Tolerance
a) Markedly increased amounts of the substance to achieve int…
hormones- pharmacology
types of adenohypophyseal hormones
somatotropic hormones
glycoprotein hormone
POMC hormones
somatotropic... glycoprotein... proopiomelanocortin (POMC)
GF... PrL
TSH (thyrotropin)... LH... FSH... CG (chorionic gonadotropin)
ACTH
types of adenohypophyseal hormones
somatotropic... glycoprotein... proopiomelanocortin (POMC)
somatotropic hormones
GF... PrL
237 terms
Pharmacology 2 Exam III
What is epilepsy?
What are some non drug therapies for e…
Why might non drug therapies for epile…
What are some screening tests utilized…
Chronic brain disorder characterized by recurrent seizures
Surgical resection (focal seizures)... Vagus nerve stimulation
Resistance to drug... Patient cannot tolerate drug... Reduce doses…
Maximal electric stimulation... Pentylenetetrazole induced seizu…
What is epilepsy?
Chronic brain disorder characterized by recurrent seizures
What are some non drug therapies for e…
Surgical resection (focal seizures)... Vagus nerve stimulation
159 terms
Pharmacology 2 Exam 1
How can the cerebral cortex be subdivi…
What are components of the limbic syst…
What is associated with the amygdala?
What is associated with the cingulate…
Based on location... Based on information processed
Amygdala... Cingulate cortex... Hippocampus... Hypothalamus... Mammilary…
Fear... Aggression
Attention... Cognition
How can the cerebral cortex be subdivi…
Based on location... Based on information processed
What are components of the limbic syst…
Amygdala... Cingulate cortex... Hippocampus... Hypothalamus... Mammilary…
289 terms
Pharm-MC TB/Malaria/Fungi/Quinolones/Sulfonamides
Anti-TBs (Pharm):... -Absorption
Anti-TBs (Pharm):... -Distribution
Anti-TBs (Pharm):... -Metabolism
Anti-TBs (Pharm):... -Excretion
All are orally absorbed, except for *Isoniazid* (IM or Oral)…
CSF Pentration: *Rifampin, Ethoionamide, Cycloserine*... Inflamm…
No metabolism: *Cycloserine*... N/A metabolism: *Capreomycin*... He…
Pee: *Isoniazid, Ethambutol, Pyrazinamide, Ethionamide*... Bile/…
Anti-TBs (Pharm):... -Absorption
All are orally absorbed, except for *Isoniazid* (IM or Oral)…
Anti-TBs (Pharm):... -Distribution
CSF Pentration: *Rifampin, Ethoionamide, Cycloserine*... Inflamm…
14 terms
Antimicrobials: Cidal vs. Static
penicillins
cephalosporins
imipenem
vancomycin
cidal
cidal
cidal
cidal
penicillins
cidal
cephalosporins
cidal
198 terms
Pharmacology 2 Exam II
What is the physiological cause of anx…
What are some things that may induce a…
In what ways do manifestations of anxi…
What are the two clinical forms of anx…
Increase of epinephrine by sympathetic NS
Life events... Primary symptom of anxiety disorder... Secondary sym…
Intensity... Duration... Presentation (symptomology)
General axiety- long lasting low grade anxiety... Panic attacks-…
What is the physiological cause of anx…
Increase of epinephrine by sympathetic NS
What are some things that may induce a…
Life events... Primary symptom of anxiety disorder... Secondary sym…
dermatological pharmacology
functions of the skin
functions of skin (cont'd)
absorption from skin
absorption: nature of the drug
∙prevent loss of essential body fluids & protect from environ…
∙calcium homeostasis... -vit D3 produced in the skin (UV light o…
nature of the drug... behavior of the vehicle... status of the skin
drug ionization... hydrophilicity... molecular weight
functions of the skin
∙prevent loss of essential body fluids & protect from environ…
functions of skin (cont'd)
∙calcium homeostasis... -vit D3 produced in the skin (UV light o…
42 terms
NAPLEX Chemo Man Drugs-MOA
altretamine
bendamustin
bleomycin
busulfan
alkylator
alkylator
misc agent: intercalating agent blocking topo II
alkylator
altretamine
alkylator
bendamustin
alkylator
37 terms
Pharmacology Exam 4 - Anti TB
What are the 5 main drugs used to trea…
How long is anti-TB therapy when using…
What is the regimen for option 1 treat…
What is the regimen for option 2 treat…
1. Ethambutol... 2. Streptomycin... 3. Pyrazinamide... 4. Rifampin... 5.…
24 weeks
1. Pyrazinamide, Rifampin, Isoniazid, and Ethambutol (or Stre…
1. Pyrazinamide, Isoniazid, Rifampin and Ethambutol (or Strep…
What are the 5 main drugs used to trea…
1. Ethambutol... 2. Streptomycin... 3. Pyrazinamide... 4. Rifampin... 5.…
How long is anti-TB therapy when using…
24 weeks
50 terms
Pharmacology Exam 4 - Anti-Malarial Drugs
What two stages of the plasmodial life…
Primaquine is the only drug that treat…
What are the four types of malaria? Wh…
Which two drugs are effective at the t…
1. Gametocidal... 2. Hypnozoitocidal... 3. Also effective at the ti…
Exoerythrotic
1. Plasmodia falciparum - most severe... 2. Plasmodia vivax - la…
1. Primaquine... 2. Pyrimethamine
What two stages of the plasmodial life…
1. Gametocidal... 2. Hypnozoitocidal... 3. Also effective at the ti…
Primaquine is the only drug that treat…
Exoerythrotic
51 terms
Cephalosporins, Penems, Vanc (Pharm) Exam IV
What happens when the R group on the 6…
What happens when the R group of the a…
What is the MOA of cephalosporins?
What are mechanisms of resistance to c…
Pharmacology is modified
Spectrum is modified
Similar to penicillins... Bind PBP and prevent cell wall cross l…
Similar to penicillins... Inability to reach target... Alteration o…
What happens when the R group on the 6…
Pharmacology is modified
What happens when the R group of the a…
Spectrum is modified
39 terms
Macrolides, Streptagramins, Misc. (Pharm) Exam IV
What is the MOA of macrolides?
What are mechanisms of resistance to m…
What are ADME characteristics of eryth…
What are therapeutic uses of erythromy…
Inhibit protein synthesis by binding 50S subunit reversibly
Reduced transport... Alteration of ribosome (chromosonal or enzy…
A:Orally absorbed but high acidity may delay... D: well distribu…
Second line after penicillin G for gram +... Some gram negativ…
What is the MOA of macrolides?
Inhibit protein synthesis by binding 50S subunit reversibly
What are mechanisms of resistance to m…
Reduced transport... Alteration of ribosome (chromosonal or enzy…
49 terms
Aminoglycosides, Tetracyclines (Pharm) Exam IV
What are some aminoglycosides?
What is the MOA of aminoglycosides?
Are aminoglycocides bactericidal or ba…
How has resistance evolved against ami…
Amikacin... Gentamicin... Netilmicin... Tobramycin
Irreversible binding to 30S subunit of ribosome --> aberran…
Cidal in growing cells
*Inactivation by enzymes (adenylase, acetylase, phosphorylase…
What are some aminoglycosides?
Amikacin... Gentamicin... Netilmicin... Tobramycin
What is the MOA of aminoglycosides?
Irreversible binding to 30S subunit of ribosome --> aberran…
90 terms
Alcohol and Anesthesia (Pharm Exam VI)
Which body systems are harmed by exces…
What are the effects of EtOH as a CNS…
What other body process can EtOH compr…
What are the mechanisms of EtOH effects?
GI- Liver, pancreas... Cardiovascular... Nervous: CNS and PNS
Disturbs balance between inhibitory and excitatory signals... La…
Fetal development
Complex w/no specific receptor ... < 10 mM = litte effect... > 20 m…
Which body systems are harmed by exces…
GI- Liver, pancreas... Cardiovascular... Nervous: CNS and PNS
What are the effects of EtOH as a CNS…
Disturbs balance between inhibitory and excitatory signals... La…
39 terms
Penicillins (Pharm) Exam IV
What is the MOA of penicillins?
What are the natural penicillins and h…
What types of microbes are the natural…
What are some specific organisms that…
Bind PBP and inhibit cell wall crosslinking
Penicillin G (parenteral)... Penicillin V (Oral)
Gram positive: cocci and bacillli... Some gram negative cocci... Sp…
Strep (Groups A,B,C,G)... E. faecalis... T. pallidum (syphilis)... Act…
What is the MOA of penicillins?
Bind PBP and inhibit cell wall crosslinking
What are the natural penicillins and h…
Penicillin G (parenteral)... Penicillin V (Oral)
46 terms
OTC Opthalmics
Dry Eye: Hallmark Symptom
Dry Eye: Causes
Dry Eye: Symptoms
Dry Eye: Goal Treatment
Foreign body senstation... Ex. grittiness
Aging... Anticholinergic medications: Diphenhydramine, Amitripty…
White or mildly red eye... Foreign body sensation... May present in…
Alleviate and control the dryness, which will help prevent po…
Dry Eye: Hallmark Symptom
Foreign body senstation... Ex. grittiness
Dry Eye: Causes
Aging... Anticholinergic medications: Diphenhydramine, Amitripty…
60 terms
Dyslipidemia
How is LDL calculated?
When does LDL become inaccurate?
What therapeutic lifestyle changes wer…
What are sources of soluble fiber?
LDL = TC - HDL - (TG/5)
TG > 200
Saturated fat < 7% calories... Cholesterol < 200 mg/day... Increase…
Oats... Pectin... Psyllium
How is LDL calculated?
LDL = TC - HDL - (TG/5)
When does LDL become inaccurate?
TG > 200
57 terms
Narcotic Analgesics
What are the types of pain?
What kind of pain do Adelta fibers res…
What kind of pain do C fibers respond…
What are some opiates?
Nociception- thermal, chemical, or mechanical... Neuropathic ... Af…
Myelinated, fast conduction... Sharp ... Well localized
Non-myelinated, slow conduction... Dull ... Burning
Phenanthrenes- morphine, codeine, thebaine... Benzylisoquinolone…
What are the types of pain?
Nociception- thermal, chemical, or mechanical... Neuropathic ... Af…
What kind of pain do Adelta fibers res…
Myelinated, fast conduction... Sharp ... Well localized
31 terms
Quinolones & Sulfonamides
What is the MOA of quinolones?
How is resistance evolved to quinolones?
How are quinolones distributed?
How are quinolones excreted?
Inhibit DNA gyrase --> inhibit DNA synthesis... Bactericidal
Alteration in DNA gyrase binding ... Decreased accumulation (dec…
Well distributed throughout... *High levels in bone, kidney, uri…
Renal (Unchanged in urine)... Bile
What is the MOA of quinolones?
Inhibit DNA gyrase --> inhibit DNA synthesis... Bactericidal
How is resistance evolved to quinolones?
Alteration in DNA gyrase binding ... Decreased accumulation (dec…
42 terms
Antimicrobial Principles Exam IV
What is chemotherapy?
What is an antibiotic?
What is an antimicrobial?
What is selective toxicity?
Treatment of disease by chemical agent... Agents unfavorably aff…
Chemical substance produced by microorganism that can inhibit…
Agent that inhibits growth or kills microorganisms (viruses t…
Drug concentration needed to inhibit microbial growth does no…
What is chemotherapy?
Treatment of disease by chemical agent... Agents unfavorably aff…
What is an antibiotic?
Chemical substance produced by microorganism that can inhibit…
104 terms
OTC Exam VI (Objectives)
How do you calculate BMI?
When is BMI considered overweight?
When is BMI considered obese?
What are the classes of obesity?
Weight (Kg)/(Height (m))^2... OR... (Weight (lbs)/(Height (inches…
25 < BMI < 30
30 ≤ BMI
30 < BMI < 35 (Class 1)... 35 ≤ BMI < 40 (Class 2)... 40 ≤ BMI (Ext…
How do you calculate BMI?
Weight (Kg)/(Height (m))^2... OR... (Weight (lbs)/(Height (inches…
When is BMI considered overweight?
25 < BMI < 30
70 terms
OTC Constipation, Gas, Diarrhea
What are common causes of constipation?
What are some medications that can cau…
What are complications and comorbiditi…
When should a patient be referred to P…
Slow transit constipation (decreased motility from lack of pa…
Calcium channel blockers... Narcotics... Antacids (Ca & Al)... Anticho…
Intestinal impaction... Anal fissure... IBS... Hemorrhoids... Volvulus... Ul…
Worsening of symptoms... Older patients (>/= 50 yrs)... Blood in st…
What are common causes of constipation?
Slow transit constipation (decreased motility from lack of pa…
What are some medications that can cau…
Calcium channel blockers... Narcotics... Antacids (Ca & Al)... Anticho…
53 terms
OTC Incontinence, Oral, Nausea (Objectives)
What is urinary incontinence?
What is stress incontinence?
What is urge incontinence?
What is overflow incontinence?
Unintentional loss or leaking of urine
Leaking urine with coughing, sneezing, standing or laughing
Involuntary bladder contraction
Bladder is chronically full or unable to void
What is urinary incontinence?
Unintentional loss or leaking of urine
What is stress incontinence?
Leaking urine with coughing, sneezing, standing or laughing
28 terms
OTC Exam IV (Objectives)
What menstrual disorders can be treate…
What are exclusions to OTC treatment o…
What are exclusions to OTC treatment o…
What would represent abnormal blood lo…
Primary dysmenorrhea... Premenstrual syndrome
Secondary dysmenorrhea (Assc w/pelvic issues)... Severe diseas…
Uncertain pattern of symptoms... Onset coincides with OCP or HRT…
Soaking through 1 or more pads/tampons for consecutive hours…
What menstrual disorders can be treate…
Primary dysmenorrhea... Premenstrual syndrome
What are exclusions to OTC treatment o…
Secondary dysmenorrhea (Assc w/pelvic issues)... Severe diseas…
23 terms
Pathophys and Tx of VTE
What is Virchow's triad?
What are examples of venous stasis?
What are examples of vascular injury?
What are examples of hypercoagulable s…
Venous stasis... Hypercoagulable state... Endothelial injury
Immobilization... CHF... CVA... Age >40... Varicose veins... Obesity... AMI... Car…
Trauma... Surgery... Central venous or pulmonary catheter... History o…
Malignancy... Estrogen... Pregnancy... Nephrotic syndrome (losing clot…
What is Virchow's triad?
Venous stasis... Hypercoagulable state... Endothelial injury
What are examples of venous stasis?
Immobilization... CHF... CVA... Age >40... Varicose veins... Obesity... AMI... Car…
90 terms
OTC Exam VII (Objectives)
What is contact dermatitis?
What is the typical presentation of ir…
What are treatment goals of irritant c…
What are characteristics of allergic c…
Inflammatory skin condition characterized by ... Inflammation... Re…
Outbreak w/i mins to hrs of exposure... Red macules... Fissures... Gla…
Relieve inflammation, tenderness, and irritation... Prevent cont…
Inflammation in response to allergen... Reaction occurs on secon…
What is contact dermatitis?
Inflammatory skin condition characterized by ... Inflammation... Re…
What is the typical presentation of ir…
Outbreak w/i mins to hrs of exposure... Red macules... Fissures... Gla…
54 terms
OTC Exam II
What is cerumen?
Why is cerumen important?
What are causes of cerumen impaction?
What are some symptoms of cerumen impa…
Ear wax... Produce by oily secretions from exocrine glands mixed…
Lubricate external ear canal... Trap dust and foreign matter... Wax…
Excess production... Mechanical trauma from attempting to clean…
Sense of fullness or pressure... Gradual hearing loss... Dull pain…
What is cerumen?
Ear wax... Produce by oily secretions from exocrine glands mixed…
Why is cerumen important?
Lubricate external ear canal... Trap dust and foreign matter... Wax…
37 terms
Heart Disease Prevention (T1 E1)
What is the difference between coronar…
What are non modifiable risk factors f…
What are modifiable risk factors for C…
In which cohort are the pooled cohort…
Coronary artery disease is the process by which coronary hear…
Age... Family history (1st degree relative usually)... Sex
Smoking... Hyperlipidemia... DM... HTN... Sedentary lifestyle... Obesity
20-39 years
What is the difference between coronar…
Coronary artery disease is the process by which coronary hear…
What are non modifiable risk factors f…
Age... Family history (1st degree relative usually)... Sex
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