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Study sets matching "virology"

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Study sets matching "virology"

52 terms
Virology
Calcicivirus (Norwalk/Noro)... Astrovirus
HSV or VZV (identical inclusions)
Rotavirus... Astrovirus... Norovirus... Adenovi…
1) BK virus (dsDNA, circular)... 2) *Ad…
Non-enveloped RNA viruses that cause diarrhea
Viral gastroenteritis
Hemorrhagic cystitis, most common viral causes.
Calcicivirus (Norwalk/Noro)... Astrovirus
Non-enveloped RNA viruses that cause diarrhea
HSV or VZV (identical inclusions)
20 terms
Virology
What are the several ways that viruses…
What are 4 examples of the Pneumotropi…
What are 6 Examples of Dermotropic Vir…
What are Viscerotropic Viruses? What a…
(Classification of Viruses)... 1. Naked & Enveloped... 2. By Tissue…
(4 Examples of Pneumotropic Viruses)... Influenza... RSV... Adenovirus…
(6 Dermotropic Viruses)... Chickenpox... Smallpox... Measles... Mumps... Rub…
(Viscerotropic Viruses)... Viruses that infect the blood and vis…
What are the several ways that viruses…
(Classification of Viruses)... 1. Naked & Enveloped... 2. By Tissue…
What are 4 examples of the Pneumotropi…
(4 Examples of Pneumotropic Viruses)... Influenza... RSV... Adenovirus…
233 terms
Virology
obligate intracellular parasites
RNA or DNA... protein coat... extracellular…
small circular RNA... no protein coat... inf…
smallpox
viruses
virion
viroid
jenner
obligate intracellular parasites
viruses
RNA or DNA... protein coat... extracellular…
virion
73 terms
Virology
What is the size range of a virus?
What is the smallest virus?
What is the largest virus?
What is the structure of virions?
Most are 20-700nm... (can be smaller)
Foot and mouth disease virus (FMDV) - 20nm
Mimivirus - 700nm
1) Nucleic acid (genome)... 2) Capsid... Some have:... 3) Lipid m…
What is the size range of a virus?
Most are 20-700nm... (can be smaller)
What is the smallest virus?
Foot and mouth disease virus (FMDV) - 20nm
55 terms
Virology
Common viruses in CSF?
Common viruses in Urine?
Common viruses in Urine RESP/NP/Nasal
Common viruses in Skkin lesions and va…
Enterovirus, HSV, VZV, mumps, and measles
CMV, Adenovirus, anterovirus, mumps, rubella, HSV
parainfluenza Common viruses in Urine... rhinovirus ... RSV, measle…
HSV, VZV, anterovirus
Common viruses in CSF?
Enterovirus, HSV, VZV, mumps, and measles
Common viruses in Urine?
CMV, Adenovirus, anterovirus, mumps, rubella, HSV
186 terms
Virology
Dimitrii Ivanovsky
Martinus Beiierinck
Friedrich Loeffler and Paul Frosch
what did early virologists discover?
1892... causative agent of tobacco mosaic virus (TMV) was not re…
1896 ... concluded that the pathogen responsible for TMV must be…
1898... observed that the causative agent of foot and mouth dise…
viruses can pass through filters and are able to replicate an…
Dimitrii Ivanovsky
1892... causative agent of tobacco mosaic virus (TMV) was not re…
Martinus Beiierinck
1896 ... concluded that the pathogen responsible for TMV must be…
181 terms
Virology
Contagium Vivum Fluidum
Yellow fever
Virion
Picornavirus, Calicivirus, Astrovirus,…
Responsible for tobacco mosaic disease
First human virus identified caused this. Its vector is the m…
the complete virus particle is known as...
Name the five families of Naked RNA viruses
Contagium Vivum Fluidum
Responsible for tobacco mosaic disease
Yellow fever
First human virus identified caused this. Its vector is the m…
16 terms
Virology
Hepadna family
Polyoma/Papilloma ... (AKA Papovaviridae)
Adeno
Herpes
Name derivation: HEPAtitis DNA... Genome: DS-Circular genome... Mor…
Name derivation: Papilloma/Polyoma/Vacuolating... Genome: DS-Cir…
Name derivation: Adenoid cell structure latent infect... Genome:…
Name derivation: "Herpein"- to creep... Genome: Ds-linear... Morpho…
Hepadna family
Name derivation: HEPAtitis DNA... Genome: DS-Circular genome... Mor…
Polyoma/Papilloma ... (AKA Papovaviridae)
Name derivation: Papilloma/Polyoma/Vacuolating... Genome: DS-Cir…
17 terms
Virology
Rhinoviruses
Enteroviruses
Parainfluenza
Influenza
Most common viral agents in humans and responsible for the co…
Viral agents responsible for polio and viral meningitis
Virus responsible for croup in kids
Virus which causes the common flu which causes fever and musc…
Rhinoviruses
Most common viral agents in humans and responsible for the co…
Enteroviruses
Viral agents responsible for polio and viral meningitis
68 terms
Virology
Plaque
PFU (plaque forming units)
Receptor
Structural protein
An area of lysis in a layer of cells, usually initiated by a…
the quantity of virions that can initiate formation of a sing…
A molecule on the cell surface to which a virus specifically…
a protein that is a component of the virion (i.e. capsid prot…
Plaque
An area of lysis in a layer of cells, usually initiated by a…
PFU (plaque forming units)
the quantity of virions that can initiate formation of a sing…
102 terms
Virology
Enveloped viruses
Naked viruses
Helical capsids
Icosahedral capsids
fragile; disrupted by stomach acid, detergents, solvents, hea…
resistant; some withstand stomach acid; transferred via fecal…
-ssRNA; enveloped in human viruses; not rigid (spaghetti-like…
enveloped or naked; formed from viral capsid proteins; nuclei…
Enveloped viruses
fragile; disrupted by stomach acid, detergents, solvents, hea…
Naked viruses
resistant; some withstand stomach acid; transferred via fecal…
36 terms
Virology
Small DNA Viruses
Adenovirus
Parvovirdae
Human Papilloma Virus (HPV)
Double Stranded Linear DNA... Non enveloped... Receptor mediated En…
Smallest DNA: single stranded... Non enveloped Icosahedral capsi…
Papillomavirus... Small non enveloped icosahedral viruses... 100+ t…
Small DNA Viruses
Adenovirus
Double Stranded Linear DNA... Non enveloped... Receptor mediated En…
25 terms
Virology
Sialic acid receptor on lung epitheliu…
Acetylcholine receptor and neuronal ce…
CD4 (primary), CCR5 and CXCR4 (chemoki…
CD3 receptor on B cells
Receptors for influenza virus
Receptors for rabies virus
receptors for HIV
receptor for Epstein-Barr virus
Sialic acid receptor on lung epitheliu…
Receptors for influenza virus
Acetylcholine receptor and neuronal ce…
Receptors for rabies virus
233 terms
Virology
Influenza virus history
Swine Flu History
avian influenza
viruses as therapeutic cancer treatmen…
Kansas as a respiratory disease, then went to Fort Riley, spr…
-National Swine Breeders Show in Cedar Rapids, IA- hog flu (1…
zoonotic... -some are no virulent (LPAI) and some are highly vir…
reovirus- can be used as an anti cancer treatment
Influenza virus history
Kansas as a respiratory disease, then went to Fort Riley, spr…
Swine Flu History
-National Swine Breeders Show in Cedar Rapids, IA- hog flu (1…
20 terms
Virology
General rules of DNA viruses
DNA viruses
Herpes viruses
Latency sites for herpesviruses
* Either naked or enveloped.... * Morphology includes icosahedra…
Enveloped: (2 sex and a pox)... 1. Hepadnavirus (HBV)... 2. Herpesv…
* All are dsDNA, enveloped viruses... 1. HSV I/II... 2. CMV... 3. EBV…
1. HSV 1: Trigeminal ganglia... 2. HSV 2: Sacral ganglia... 3. VZV:…
General rules of DNA viruses
* Either naked or enveloped.... * Morphology includes icosahedra…
DNA viruses
Enveloped: (2 sex and a pox)... 1. Hepadnavirus (HBV)... 2. Herpesv…
651 terms
Virology
Which viruses are more fragile: envelo…
Why are enveloped viruses most fragile?
Does Parvovirus have an envelope?
T/F: Viruses have a single replication…
Enveloped viruses are most fragile.
They don't survive well outside the host & are susceptible to…
No, which is why it is really hard to get rid of!
False; there is great diversity in how viruses replicate, & t…
Which viruses are more fragile: envelo…
Enveloped viruses are most fragile.
Why are enveloped viruses most fragile?
They don't survive well outside the host & are susceptible to…
172 terms
Virology
Lecture 2-1: Virus Structure and Class…
Virology
Background and Significance
Discovery of Viruses
...
The molecular biology of virus replication and pathogenesis,…
-All forms of life have viruses... -Viruses and their hosts have…
"Filterable Agents" - bacteria can be filtered (220nm pores)…
Lecture 2-1: Virus Structure and Class…
...
Virology
The molecular biology of virus replication and pathogenesis,…
209 terms
Virology
What is a virus?
List the key steps in the virus replic…
True or false... positive RNA is same as…
Why are viruses obligate intracellular…
Small (17-300nm), obligate intracellular parasites. In their…
Attachment/adsorption, Penetration, Uncoating, Synthesis, Ass…
true
They lack the complex energy-generating machinery necessary f…
What is a virus?
Small (17-300nm), obligate intracellular parasites. In their…
List the key steps in the virus replic…
Attachment/adsorption, Penetration, Uncoating, Synthesis, Ass…
229 terms
Virology
Contageum Vivum Fluidum
The first virus discovered
T/F All viruses cause disease
The first animal virus agent to pass t…
"Contagious living fluid" was used to describe first virus
Tobacco mosaic virus; This virus can cause disease in tobacco…
False, not all viruses cause disease
Foot and mouth disease
Contageum Vivum Fluidum
"Contagious living fluid" was used to describe first virus
The first virus discovered
Tobacco mosaic virus; This virus can cause disease in tobacco…
21 terms
Virology
non-enveloped virus
enveloped virus
3 basic schemas of viral classification
Virion
Diseases with which they are associated, tissues or geographi…
virus particle that is capable of infecting a new host cell
non-enveloped virus
enveloped virus
101 terms
Virology
What is the target cells and receptors…
What is the target cells and receptors…
What is the target cells and receptors…
What is the target cells and receptors…
Th cells, macrophage and microglia. ... CD4, CCR5 and CXCR4.
B cells... receptors: CD21=CR2
Neurons... Acetylcholine receptor.
Respiratory epithelial cells.... ICAM-1
What is the target cells and receptors…
Th cells, macrophage and microglia. ... CD4, CCR5 and CXCR4.
What is the target cells and receptors…
B cells... receptors: CD21=CR2
107 terms
Virology
What is a virus?
T or F? Viruses are alive.
T or F? Viruses are filterable agents.
T or F? Virus genomes are made up of b…
An obligate intracellular parasite
False, they are not alive.
True
False, a virus genome is made up of either RNA or DNA, but no…
What is a virus?
An obligate intracellular parasite
T or F? Viruses are alive.
False, they are not alive.
48 terms
Virology
Describe the size of viruses
Describe the metabolism of viruses
Describe the genome of viruses?
Describe the host range of viruses
size: Most viruses are extremely small (0.2-0.02 microns)
Not considerate true obligate intracellular parasites, must "…
Viruses can be DNA or RNA, ds or ss, circular or linear, in o…
Most viruses are able to infect specific types of cells of on…
Describe the size of viruses
size: Most viruses are extremely small (0.2-0.02 microns)
Describe the metabolism of viruses
Not considerate true obligate intracellular parasites, must "…
7 terms
Virology
List the pox viruses
List the herpes viruses
List the circo viruses
List the parvo viruses
Vaccinia, Cowpox, Pseudocowpox, Sheeppox/Goatpox/Lumpy skin d…
Equine herpes virus 1-4, Avian herpes virus 1 & 2, Canine her…
Chicken anemia virus, psittacine beak & feather disease, porc…
Canine parvovirus, feline panleukopenia, porcine parvovirus,…
List the pox viruses
Vaccinia, Cowpox, Pseudocowpox, Sheeppox/Goatpox/Lumpy skin d…
List the herpes viruses
Equine herpes virus 1-4, Avian herpes virus 1 & 2, Canine her…
38 terms
Virology
Mnemonic for live attenuated vaccines
Can you have a single stranded DNA vir…
Can you have double stranded RNA virus?
Where do viruses replicate?
Live! One night only! See SMALL YELLOW ROTating CHICKENs get…
Yes - only one... Parvovirus
Yes - only one... Reoviridae
DNA - in nucelus (except poxvirus)... RNA - in cytoplasm (except…
Mnemonic for live attenuated vaccines
Live! One night only! See SMALL YELLOW ROTating CHICKENs get…
Can you have a single stranded DNA vir…
Yes - only one... Parvovirus
77 terms
Virology
Virus
Virion
Positive Sense ss RNA
Negative Sense ss RNA
obligate intracellular organism which needs a host to replica…
the complete, infective form of a virus outside the host cell…
virus RNA that can be translated directly to protein
virus RNA that needs to be synthesized to positive sense RNA…
Virus
obligate intracellular organism which needs a host to replica…
Virion
the complete, infective form of a virus outside the host cell…
71 terms
Virology
Living or not
Virus Size
Syncytia
Adenoids
- Non-living outside of the cell = virions... - Inside the cell…
Giant virus = girus
- Fusion of infected cells
- Enlarged mass of lymphoid tissue in upper pharynx
Living or not
- Non-living outside of the cell = virions... - Inside the cell…
Virus Size
Giant virus = girus
8 terms
Virology
Adenovirus
Herpes Virus
Varicella-Zoster virus
Rotavirus
-Naked, icosahedral... -Respiratory and gastrointestinal... -Shed i…
Enveloped ... Icosahedral capsid... Lysogenic/latent presistance... He…
-Causes chickenpox and shingles... -Usually clinically apparent…
-Causes severe diarrhea in infants and small children... -Specie…
Adenovirus
-Naked, icosahedral... -Respiratory and gastrointestinal... -Shed i…
Herpes Virus
Enveloped ... Icosahedral capsid... Lysogenic/latent presistance... He…
19 terms
virology
are virus living
viral structures
optional structures
how do virus fit into the taxonomic hi…
no. they are active or inactive,... lack cell structures like me…
1, nucleic acid. a short piece of DNA or RNA... 2, capsid, a pro…
1, envelope. covering the outside of capsid, phospholipid lay…
order, family, genus, species
are virus living
no. they are active or inactive,... lack cell structures like me…
viral structures
1, nucleic acid. a short piece of DNA or RNA... 2, capsid, a pro…
12 terms
Virology
Characteristics of Viruses
Virus life cycle
Gapped DNA are repaired with ______ be…
Receptor
Genes (DNA or RNA); Protein shell or coat; Can establish them…
Attachment; Penetration; Translation; Genome replication; Vir…
Reverse transcriptase
Cell surface molecules we can see from the outside
Characteristics of Viruses
Genes (DNA or RNA); Protein shell or coat; Can establish them…
Virus life cycle
Attachment; Penetration; Translation; Genome replication; Vir…
97 terms
Virology
Virus
viruses reproduce
viruses
independent metabolism
infectious genetic element possesing a protein coat and nucle…
only within living host cells
lack independent metabolism
no repiratory or biosynthetic functions
Virus
infectious genetic element possesing a protein coat and nucle…
viruses reproduce
only within living host cells
34 terms
Virology
Viruses are..
Criteria consistent among viruses
Nucleocapsid =
Virion =
- submicroscopic, obligate intracellular parasites ... - infecti…
- one type of nucleic acid (RNA or DNA)... - virus reproduces on…
- Nucleic acid (either DNA or RNA) + capsid (surrounding prot…
- entire infectious unit... - Nucleocapsid +/- envelope
Viruses are..
- submicroscopic, obligate intracellular parasites ... - infecti…
Criteria consistent among viruses
- one type of nucleic acid (RNA or DNA)... - virus reproduces on…
38 terms
Virology
Virus
Virion
Size of virus
Pathogen
mysterious elements in fluid ... consist of nucleic aid genome p…
infectious virus particle
nanometer size ranges from 20-150nm in diameter typically vir…
a disease causing virus or other microorganism
Virus
mysterious elements in fluid ... consist of nucleic aid genome p…
Virion
infectious virus particle
77 terms
Virology
Edward Jenner
Louis Pasteur
Dimiti Iwanowski
Emory Ellis and Max Delbruck
used cowpox to create smallpox vaccine
Worked on RV against pathogenic virus
described tobacco mosaic virus, the first "filterable" infect…
postulate the "one step virus growth cycle" - viruses do not…
Edward Jenner
used cowpox to create smallpox vaccine
Louis Pasteur
Worked on RV against pathogenic virus
83 terms
Virology
Viruses are
Obligate intracellular parasites means
Mechanisms of Virus interaction w/ Hos…
Tissue Tropism:
Obligate intracellular parasites, that is, they ... *--Are NOT l…
Cannot produce outside of the cell; the parasite relies entir…
1. Recognize Cell for which it has Tropism... 2. Attachment... 3. P…
the cells and tissues of a host which support growth of a par…
Viruses are
Obligate intracellular parasites, that is, they ... *--Are NOT l…
Obligate intracellular parasites means
Cannot produce outside of the cell; the parasite relies entir…
18 terms
Virology
This is a very small, non cellular mic…
The virus genome directs the synthesis…
Nucleic acid genome ... Protein capsid ... L…
This is composed of DNA / RNA ... it can…
Define a virus
Describe the replication of a virus
What are viruses composed of ? Draw the structure of a virus
Describe the virus genome
This is a very small, non cellular mic…
Define a virus
The virus genome directs the synthesis…
Describe the replication of a virus
133 terms
Virology
Smallest virus in size (icosahedral)
Largest virus in size
Parvo genome
Circo genome
circovirus
Pandora Virus
linear ssDNA
circular ssDNA
Smallest virus in size (icosahedral)
circovirus
Largest virus in size
Pandora Virus
42 terms
VIROLOGY
Coronaviruses
Noraviruses
Parvovirus
Rubivirus (Rubella)
+sense RNA forming helix, enveloped w/glycoprotein E2... *infec…
+sense RNA, naked viruses with icosahedral capsid, special Vp…
smallest DNA viruses... Parvovirus B19: non enveloped icosahedra…
member of Togaviridae... -enveloped + sense ssRNA, icosahedral…
Coronaviruses
+sense RNA forming helix, enveloped w/glycoprotein E2... *infec…
Noraviruses
+sense RNA, naked viruses with icosahedral capsid, special Vp…
89 terms
Virology
Paramyxoviruses
Palivizumab
Measles
Mumps
Causes disease in children... 1. Parainfluenza virus-->seal lik…
Monoclonal antibody against F protein ... Prevents pneumonia ca…
paramyxovirus... Characterized by a prodromal fever and the "3…
Paramyxovirus-->rubulavirus ... RNA virus ... Part of the MMR vacc…
Paramyxoviruses
Causes disease in children... 1. Parainfluenza virus-->seal lik…
Palivizumab
Monoclonal antibody against F protein ... Prevents pneumonia ca…
161 terms
Virology
1. Primary... 2. Latent... 3. Reactivated
1. HSV-1... 2. HSV-2... 3. VSV
•Orthomyxovirus family... •ssRNA-segmente…
Neuraminidase
3 steps of herpes virus infection
Alpha herpes virus family
Influenza virus... •Family?... •Genome?... •Shape? ... •Capsule?
Influenza virulence factor... •Cleaves sialic acid receptors to…
1. Primary... 2. Latent... 3. Reactivated
3 steps of herpes virus infection
1. HSV-1... 2. HSV-2... 3. VSV
Alpha herpes virus family
34 terms
Virology
HSV-1
HSV-2
Varicella-zoster (VZV)
Epstein-Barr virus (EBV), also called…
DNA virus.... Enveloped. DS and linear genome. ... HSV- 1: First si…
Genital (and some oral) lesions= herpes genitalis. Neonatal h…
Varicella-zoster (chickenpox, shingles), encephalitis, pneumo…
Mononucleosis. Characterized by fever, hepatosplenomegaly, ph…
HSV-1
DNA virus.... Enveloped. DS and linear genome. ... HSV- 1: First si…
HSV-2
Genital (and some oral) lesions= herpes genitalis. Neonatal h…
24 terms
Virology
Capsule symmetry
Naked capsuled viruses
Enveloped capsuled viruses
Steps in Viral Production
Helical or icosahedral
Hardy to environment; easily survive outside host and transmi…
Prefer wet environments (Blood); are less hardy; tend to bud
Recognition -> adhesion/attaching -> penetrating and uncoatin…
Capsule symmetry
Helical or icosahedral
Naked capsuled viruses
Hardy to environment; easily survive outside host and transmi…
80 terms
Virology
dsDNA viruses
RNA ss -
RNA ss+
dsRNA viruses
Herpes simplex, HH6 (roseola), HH8 (Kaposi)... CMV... Varicella-zos…
Orthomyxoveridae (segmented genome)... Filovirus
Parvovirus B19... retroviruses: HIV, HTLV
Reoviruses... rotavirus
dsDNA viruses
Herpes simplex, HH6 (roseola), HH8 (Kaposi)... CMV... Varicella-zos…
RNA ss -
Orthomyxoveridae (segmented genome)... Filovirus
66 terms
Virology
HIV genome
HIV virion
Parts of HIV genome
PrGAG
+ssRNA... 9750 ntds
100 nm... enveloped
PrGAG... Prenv... PrGAGpol
4 structural proteins
HIV genome
+ssRNA... 9750 ntds
HIV virion
100 nm... enveloped
30 terms
Virology
Recombination
Reassortment
Complementation
Phenotype Mixing
2 chromosomes exchanging genes with base sequence homology
Viruses with segmented genomes --> Pandemic H1N1
virus 1 has mutation to create nonfunctional protein, virus 2…
Simultaneous infection with 2 viruses... Virus A takes Virus B's…
Recombination
2 chromosomes exchanging genes with base sequence homology
Reassortment
Viruses with segmented genomes --> Pandemic H1N1
53 terms
Virology
Viruses are not considered as living o…
Size range of a virus
Average size of a virus
Nutrition of a virus
They do not have a cellular organization.
20nm - 300nm
100nm
Obligate intracellular parasite
Viruses are not considered as living o…
They do not have a cellular organization.
Size range of a virus
20nm - 300nm
43 terms
Virology
Picornavirus (ssRNA virus)
Hepadnavirus (partially circular doubl…
Flavivirus like (ssRNA virus)
In liver pathology, a ground glass hep…
What kind of virus is the hepatitis A virus?
What type of virus is the hepatitis B virus?
What kind of virus is the hepatitis C virus?
Histologic buzz word in HBV infection.
Picornavirus (ssRNA virus)
What kind of virus is the hepatitis A virus?
Hepadnavirus (partially circular doubl…
What type of virus is the hepatitis B virus?
446 terms
Virology
What 3 scientists thought there was an…
What scientists discovered DNA is the…
What did Stanley do in 1935?
Who was the first to culture viruses a…
Brenner... Jacob... Meselson... 1961
Hershey and Chase... P32 for DNA... S35 for protein... labeled bacteri…
purification/crystalization of TMV... Bawden and Pirie saw that…
Steinhardt Harde... Syphilus... Rabies... Vaccina
What 3 scientists thought there was an…
Brenner... Jacob... Meselson... 1961
What scientists discovered DNA is the…
Hershey and Chase... P32 for DNA... S35 for protein... labeled bacteri…
43 terms
Virology
Picornavirus (ssRNA virus)
Hepadnavirus (partially circular doubl…
Flavivirus like (ssRNA virus)
In liver pathology, a ground glass hep…
What kind of virus is the hepatitis A virus?
What type of virus is the hepatitis B virus?
What kind of virus is the hepatitis C virus?
Histologic buzz word in HBV infection.
Picornavirus (ssRNA virus)
What kind of virus is the hepatitis A virus?
Hepadnavirus (partially circular doubl…
What type of virus is the hepatitis B virus?
43 terms
Virology
Picornavirus (ssRNA virus)
Hepadnavirus (partially circular doubl…
Flavivirus like (ssRNA virus)
In liver pathology, a ground glass hep…
What kind of virus is the hepatitis A virus?
What type of virus is the hepatitis B virus?
What kind of virus is the hepatitis C virus?
Histologic buzz word in HBV infection.
Picornavirus (ssRNA virus)
What kind of virus is the hepatitis A virus?
Hepadnavirus (partially circular doubl…
What type of virus is the hepatitis B virus?
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